• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Luteolin-6-C-glucoside
    Information
    CAS No. 4261-42-1 Price $148 / 20mg
    Catalog No.CFN98137Purity>=98%
    Molecular Weight448.38Type of CompoundFlavonoids
    FormulaC21H20O11Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Weizmann Institute of Science (Israel)
  • Vin?a Institute of Nuclear Scien... (Serbia)
  • The Vancouver Prostate Centre (V... (Canada)
  • University of Wisconsin-Madison (USA)
  • Korea Food Research Institute(KF... (Korea)
  • University of Illinois (USA)
  • Center for protein Engineering (... (Belgium)
  • Semmelweis Unicersity (Hungary)
  • University of Fribourg (Switzerland)
  • MTT Agrifood Research Finland (Finland)
  • University of Liège (Belgium)
  • More...
  • Package
    Featured Products
    Nodakenetin

    Catalog No: CFN98788
    CAS No: 495-32-9
    Price: $268/10mg
    Mulberroside F

    Catalog No: CFN90794
    CAS No: 193483-95-3
    Price: $398/10mg
    Mulberroside A

    Catalog No: CFN99586
    CAS No: 102841-42-9
    Price: $100/20mg
    3-O-Caffeoylquinic acid methyl ester

    Catalog No: CFN92573
    CAS No: 123483-19-2
    Price: $198/10mg
    Dihydrokavain

    Catalog No: CFN90536
    CAS No: 587-63-3
    Price: $318/20mg
    Biological Activity
    Description: Luteolin-6-C-glucoside has antioxidant activity.
    In vitro:
    Food Chem Toxicol. 2013 May;55:121-8. doi: 10.1016/j.fct.2012.12.051.
    Flavonoids profiles, antioxidant, acetylcholinesterase inhibition activities of extract from Dryoathyrium boryanum (Willd.) Ching.[Pubmed: 23313795]
    The profiles and bioactivities of flavonoids extracted from Dryoathyrium boryanum (Willd.) Ching were investigated.
    METHODS AND RESULTS:
    The total flavonoids content in extract from D. boryanum is about 145.8mg/g. By means of HPLC-DAD-ESI-MS, the main flavonoids in D. boryanum were tentatively identified as 3-hydroxyphloretin 6'-O-hexoside, quercetin-7-hexoside, apigenin7-O-glucoside, luteolin 7-O-glucoside, apigenin 7-O-galactoside, acacetin 7-O-(α-D-apio-furanosyl) (1→6)-β-d-glucoside, 3-hydroxy phloretin 6-O-hexoside, Luteolin-6-C-glucoside. 0.21mg/ml flavonoids extract from D. boryanum showed very strong superoxide anion radical scavenging potential, which is higher than that of rutin (0.25mg/ml). The extract (0.21mg/ml of flavonoids) from D. boryanum exhibited similar DPPH scavenging potential with that of rutin (0.25mg/ml). However, rutin (0.25mg/ml) showed a significantly higher reducing power and ABTS scavenging potential than that of 0.21mg/ml flavonoids extract from D. boryanum.
    CONCLUSIONS:
    It had no effect on acetylcholinesterase. D. boryanum can be considered as a medicinal plant and the flavonoids from D. boryanum are excellent antioxidants.
    In vivo:
    Biosci Biotechnol Biochem. 2006 Mar;70(3):718-21.
    Antihypertensive effect of an extract of Passiflora edulis rind in spontaneously hypertensive rats.[Pubmed: 16556991]
    Orally administered methanol extract of Passiflora edulis rind (10 mg/kg or 50 mg/kg) or luteolin (50 mg/kg), which is one of consistent polyphenols of the extract, significantly lowered systolic blood pressure in spontaneously hypertensive rats (SHRs).
    METHODS AND RESULTS:
    Quantitative analysis by liquid chromatography tandem mass spectrometry (LC-MS/MS) showed that the extract contained 20 microg/g dry weight of luteolin and 41 microg/g dry weight of Luteolin-6-C-glucoside. It also contained gamma-aminobutyric acid (GABA, 2.4 mg/g dry weight by LC-MS/MS or 4.4 mg/g dry weight by amino acid analysis) which has been reported to be an antihypertensive material.
    CONCLUSIONS:
    Since the extract contained a relatively high concentration of GABA, the antihypertensive effect of the extract in SHRs might be due mostly to the GABA-induced antihypertensive effect and partially to the vasodilatory effect of polyphenols including luteolin.
    Luteolin-6-C-glucoside Description
    Source: The herbs of Polygonum orientale Linn.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Picrasidine Q

    Catalog No: CFN92205
    CAS No: 101219-61-8
    Price: $388/10mg
    Polyporenic acid C

    Catalog No: CFN92739
    CAS No: 465-18-9
    Price: $333/5mg
    Oroselol

    Catalog No: CFN95001
    CAS No: 1891-25-4
    Price: $358/5mg
    3-Epidehydropachymic acid

    Catalog No: CFN92738
    CAS No: 168293-15-0
    Price: $338/5mg
    3,4-O-dimethylcedrusin

    Catalog No: CFN95026
    CAS No: 166021-14-3
    Price: $388/10mg
    Ganoderic acid L

    Catalog No: CFN95022
    CAS No: 102607-24-9
    Price: $413/5mg
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $592/5mg
    Ganoderic acid B

    Catalog No: CFN92052
    CAS No: 81907-61-1
    Price: $328/10mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2303 mL 11.1513 mL 22.3025 mL 44.605 mL 55.7563 mL
    5 mM 0.4461 mL 2.2303 mL 4.4605 mL 8.921 mL 11.1513 mL
    10 mM 0.223 mL 1.1151 mL 2.2303 mL 4.4605 mL 5.5756 mL
    50 mM 0.0446 mL 0.223 mL 0.4461 mL 0.8921 mL 1.1151 mL
    100 mM 0.0223 mL 0.1115 mL 0.223 mL 0.4461 mL 0.5576 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Indian J Exp Biol. 2015 Apr;53(4):208-15.
    Flavonoid profile and antioxidant activities of methanolic extract of Hyparrhenia hirta (L.) Stapf.[Pubmed: 26011981]

    METHODS AND RESULTS:
    In this study, we report isolation of flavonoids, viz., 3-O-methylquercetin, tangeritin, luteolin-7-O-glucoside, luteolin, apigenin-7-O-glucoside, apigenin-8-C-glucoside, luteolin-8-C-glucoside, Luteolin-6-C-glucoside, diosmetin and catechin from the methanolic extract of Hyparrhenia hirta employing high performance liquid chromatography and liquid chromatography-electrospray ionization-tandem mass spectrometry. The total phenolic content of H. hirta extract was 105.58 ± 0.1 mg gallic acid equivalents/g of plant extract while the total flavonoid content was 45.20 ± 0.2 mg quercetin equivalents/g of plant extract and the total condensed tannin were 72.35 ± 0.7 mg catechin equivalents/g of plant extract by reference to standard curve. The antioxidant activity was assayed through the antioxidant capacity by phosphomolybdenum assay, the reducing power assay and the radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl method.
    CONCLUSIONS:
    The extract showed dose dependant activity in all the three assays.