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Macrocarpal D
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Product Name Macrocarpal D
Price:
CAS No.: 142647-71-0
Catalog No.: CFN99471
Molecular Formula: C28H40O6
Molecular Weight: 472.6 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Yellow powder
Source: The branches of Eucalyptus globulus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Macrocarpal D is a HIV-RTase inhibitor. It has antibacterial activity.
Targets: HIV-RTase | Antifection
In vitro:
Tetrahedron Letters, 1992, 33(21):2983-2986.
Macrocarpals: HIV-RTase inhibitors of Eucalyptus globulus.[Reference: WebLink]

METHODS AND RESULTS:
Five HIV-RTase inhibitors, macrocarpals A-E(macrocarpal A, macrocarpal B, macrocarpal C, Macrocarpal D, macrocarpal E), have been isolated from Eucalyptus globulus. X-ray diffraction studies as well as spectral and chemical investigations established the structures 1, 2, 3, 12, and 13, respectively.
Macrocarpal D Description
Source: The branches of Eucalyptus globulus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.116 mL 10.5798 mL 21.1595 mL 42.3191 mL 52.8989 mL
5 mM 0.4232 mL 2.116 mL 4.2319 mL 8.4638 mL 10.5798 mL
10 mM 0.2116 mL 1.058 mL 2.116 mL 4.2319 mL 5.2899 mL
50 mM 0.0423 mL 0.2116 mL 0.4232 mL 0.8464 mL 1.058 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4232 mL 0.529 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of the Agricultural Chemical Society of Japan, 1992, 56(10):1570-1576.
Isolation and Characterization of Macrocarpals B—G Antibacterial Compounds from Eucalyptus macrocarpa.[Reference: WebLink]

METHODS AND RESULTS:
Six novel phloroglucinol dialdehyde diterpene derivatives (macrocarpal B, macrocarpal C, Macrocarpal D, macrocarpal E, macrocarpal F, macrocarpal G), which have antibacterial activity, were isolated from leaves of Eucalyptus macrocarpa. These compounds have closely related structures, the molecular formula for B—F being C28H40O6, and that of G being C28H38O5.
CONCLUSIONS:
The structures of macrocarpals B, D, and G were analyzed by means of NMR analyses.
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Soyasaponin Ac

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Saponin

Catalog No: CFN70204
CAS No: 8047-15-2
Price: $30/20mg
Salvianolic acid A

Catalog No: CFN99161
CAS No: 96574-01-5
Price: $128/20mg
3,29-Dibenzoyl karounitriol

Catalog No: CFN90576
CAS No: 873001-54-8
Price: $218/20mg
Clerosterol

Catalog No: CFN90787
CAS No: 2364-23-0
Price: $ / mg
Bergapten

Catalog No: CFN98766
CAS No: 484-20-8
Price: $40/20mg
Albiflorin

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Damulin B

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CAS No: 1202868-75-4
Price: $288/5mg
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