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    Methylisopelletierine
    Methylisopelletierine
    Information
    CAS No. 18747-42-7 Price
    Catalog No.CFN99865Purity>=98%
    Molecular Weight155.2 Type of CompoundAlkaloids
    FormulaC9H17NOPhysical DescriptionOil
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • Biological Activity
    Description: N-Methylisopelletierine has hepatoprotective activity.
    Methylisopelletierine Description
    Source: The herbs of Sedum sarmentosum Bunge
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.4433 mL 32.2165 mL 64.433 mL 128.866 mL 161.0825 mL
    5 mM 1.2887 mL 6.4433 mL 12.8866 mL 25.7732 mL 32.2165 mL
    10 mM 0.6443 mL 3.2216 mL 6.4433 mL 12.8866 mL 16.1082 mL
    50 mM 0.1289 mL 0.6443 mL 1.2887 mL 2.5773 mL 3.2216 mL
    100 mM 0.0644 mL 0.3222 mL 0.6443 mL 1.2887 mL 1.6108 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Archives of Biochemistry & Biophysics, 1957, 69(2):27-32.
    Investigation of the alkaloids of Punica Granatum L. by partition chromatography.[Reference: WebLink]
    In recent literature doubts are expressed about the accepted structure of the anthelmintic substance pelletierine, one of the four alkaloids said to occur in the bark of the pomegranate tree (Punica granatum L.) It has been suggested that the “pelletierine” of the literature is in reality isopelletierine, which would reduce the number of alkaloidal components to three.
    METHODS AND RESULTS:
    The present investigation reports on the analyses by means of partition chromatography on paper of two samples of commercial “pelletierine sulphate” and of an extract made of pomegranate bark. Four (or five) spots were found, three of which had RF‐values identical with those of synthetic pseudopelletierine, d,l‐isopelletierine and d,l‐Methylisopelletierine.
    CONCLUSIONS:
    This is a convenient way of establishing the presence of these three compounds in pharmaceutical “pelletierine” preparations and of establishing the presence of one (or two) more substances not yet identified.