• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    CAS No. 88546-96-7 Price
    Catalog No.CFN97453Purity>=98%
    Molecular Weight276.3 Type of CompoundCoumarins
    FormulaC15H16O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Korea Institute of Oriental Med... (Korea)
  • University of Hertfordshire (United Kingdom)
  • Melbourne University (Australia)
  • Washington State University (USA)
  • Kamphaengphet Rajabhat University (Thailand)
  • Uniwersytet Gdański (Poland)
  • Monash University (Australia)
  • University of Eastern Finland (Finland)
  • Tokyo Woman's Christian University (Japan)
  • Charles University in Prague (Czech Republic)
  • Universidade de Franca (Brazil)
  • More...
  • Package
    Featured Products

    Catalog No: CFN92027
    CAS No: 20493-56-5
    Price: $258/10mg
    3-O-Caffeoylquinic acid methyl ester

    Catalog No: CFN92573
    CAS No: 123483-19-2
    Price: $198/10mg
    Neochamaejasmine A

    Catalog No: CFN92151
    CAS No: 90411-13-5
    Price: $418/5mg
    Viscidulin III

    Catalog No: CFN97488
    CAS No: 92519-91-0
    Price: $413/5mg
    Delta 5-avenasterol

    Catalog No: CFN92239
    CAS No: 18472-36-1
    Price: $510/5mg

    Catalog No: CFN92172
    CAS No: 22688-79-5
    Price: $198/10mg

    Catalog No: CFN98798
    CAS No: 50656-77-4
    Price: $453/5mg
    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Cytotoxic Compound Library
  • Anti-plant-germination and growth Compound Library
  • Anticholinesterase Compound Library
  • Anti-tumor promoting activity Compound Library
  • Coumarins Compound Library
  • Biological Activity
    Description: Minumicrolin is a plant growth inhibitor against the 2nd leaf sheath elongation of rice seedlings. Murrangatin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100, it might be valuable anti-tumor-promoting agents. Minumicrolin shows mild butyrylcholinesterase inhibition activity.
    In vitro:
    Cancer Lett. 1999 Apr 26;138(1-2):87-92.
    Anti-tumor-promoting effects of 8-substituted 7-methoxycoumarins on Epstein-Barr virus activation assay.[Pubmed: 10378778 ]

    In a search for anti-tumor-promoting agents, we carried out a primary screening of twenty-nine 8-substituted and four 6-substituted derivatives of 7-methoxycoumarins isolated from plants of the Murraya and/or Citrus species (Rutaceae), examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. This investigation indicated that the prenyl (3-methyl-2-butenyl) or 2-hydroxy-3-methylbutyl (or butenyl) unit as an isoprenoid moiety at C-8 on the 7-methoxycoumarin nucleus plays an important role in the anti-tumor-promoting activity.
    Some of the 8-substituted 7-methoxycoumarins isolated from Murraya species, murrangatin (7), Minumicrolin (10) and chloticol (18), were found to significantly inhibit EBV-EA activation, and preserved the high viability of Raji cells, suggesting that 7, 10 and 18 might be valuable anti-tumor-promoting agents.
    J Asian Nat Prod Res. 2008 May-Jun;10(5-6):515-9.
    Two new coumarins from Murraya paniculata.[Pubmed: 18470803 ]

    Two new coumarins, murrmeranzin (1) and murralonginal (2), together with four known compounds Minumicrolin (3), murrangatin (4), meranzin hydrate (5) and hainanmurpanin (6) have been isolated from the aerial parts of Murraya paniculata. The structures of these compounds were determined through spectral analysis.
    Minumicrolin (3) showed mild butyrylcholinesterase inhibition activity.
    Biosci Biotechnol Biochem. 2000 Feb;64(2):420-3.
    Coumarin-related compounds as plant growth inhibitors from two rutaceous plants in Thailand.[Pubmed: 10737204 ]

    Chemical investigation of naturally occurring plant growth inhibitors from Rutaceous plants in Thailand led us to identify five 7-methoxycoumarins and one 5,7-dimethoxycoumarin from Murraya paniculata, and six furanocoumarins from Citrus aurantifolia.
    Of these compounds, murranganon senecioate (1) is a new natural compound found in M. paniculata. Minumicrolin (6) was found to be highly active against the 2nd leaf sheath elongation of rice seedlings.
    Minumicrolin Description
    Source: The herbs of Murraya exotica L
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds

    Catalog No: CFN92172
    CAS No: 22688-79-5
    Price: $198/10mg
    Epimedin B1

    Catalog No: CFN95017
    CAS No: 133137-58-3
    Price: $268/5mg
    Physalin O

    Catalog No: CFN95097
    CAS No: 120849-18-5
    Price: $413/5mg

    Catalog No: CFN95106
    CAS No: 38274-00-9
    Price: $388/5mg

    Catalog No: CFN96389
    CAS No: 30508-27-1
    Price: $388/5mg

    Catalog No: CFN92750
    CAS No: 5989-02-6
    Price: $388/5mg
    Angelol H

    Catalog No: CFN91925
    CAS No: 83247-73-8
    Price: $338/5 mg
    3,6'-Disinapoyl sucrose

    Catalog No: CFN90578
    CAS No: 139891-98-8
    Price: $138/20mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6193 mL 18.0963 mL 36.1925 mL 72.3851 mL 90.4814 mL
    5 mM 0.7239 mL 3.6193 mL 7.2385 mL 14.477 mL 18.0963 mL
    10 mM 0.3619 mL 1.8096 mL 3.6193 mL 7.2385 mL 9.0481 mL
    50 mM 0.0724 mL 0.3619 mL 0.7239 mL 1.4477 mL 1.8096 mL
    100 mM 0.0362 mL 0.181 mL 0.3619 mL 0.7239 mL 0.9048 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Structure Identification:
    Arch Pharm Res. 2011 Apr;34(4):527-31.
    C-7 oxygenated coumarins from the fruits of Micromelum minutum.[Pubmed: 21544717 ]

    A new 7-oxygenated coumarin, 7-demethylmurralonginol isovalerate (1), and a new natural product, murralonginol (2), together with seven known 7-oxygenated coumarins, murralonginol isovalerate (3), murralongin (4), micromelin (5), scopoletin (6), microminutin (7), murrangatin (8), and Minumicrolin (9), were isolated from the fruits of Micromelum minutum. The structures of these compounds were established on the basis of their 1D and 2D NMR spectroscopic data.
    Among these isolates, compounds 2 and 4 - 9 exhibited cytotoxicity against cholangiocarcinoma cell line, KKU-100.