ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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More articles cited ChemFaces products.
Phytomedicine1 Feb. 2018;Food Research InternationalApr. 2018;Badan Litbangkes Kemenkes RINo 4 (2016)Horticultural Science2016Am J Chin Med.2015 Jul 30:1-22.
J Agric Food Chem. 2017 Apr 5Naunyn Schmiedebergs Arch Pharmacol. 2017 Jul 21. Hum Exp Toxicol. 2016 Dec 9.J Pharm Biomed Anal.2018 Mar 20;BMC Complement Altern Med.2016 Jul 13
Int J Oncol. 2016 Oct;49(4)Univ. of Limpopo2016JPCMarch 16, 2017Anticancer Res.2014 Jul;34(7):3505-9.
Our products had been exported to the following research institutions and universities, And still growing.
University of Amsterdam (Netherlands)Institute of Tropical Disease Un... (Indonesia)Yale University (USA)University of South Australia (Australia)
Sant Gadge Baba Amravati Univers... (India)Molecular Biology Institute of B... (Spain)Semmelweis Unicersity (Hungary)The University of Newcastle (Australia)
Heinrich-Heine-University Düsse... (Germany)S.N.D.T. Women's University (India)University of Hertfordshire (United Kingdom)
||Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. It can reduce seedling growth and disrupt root development, the IC50 value of 6.9 ug/mL . Neochamaejasmine B has antibacterial activity on Gram-positive bacterium and Gram-negative bacterium.
|Phytochemistry. 2014 Oct;106:61-8. |
|Phytotoxic flavonoids from roots of Stellera chamaejasme L. (Thymelaeaceae).[Pubmed: 25096753 ]|
|Allelopathy, the negative effect on plants of chemicals released to the surroundings by a neighboring plant, is an important factor which contributes to the spread of some weeds in plant communities.
METHODS AND RESULTS:
In this field, Stellera chamaejasme L. (Thymelaeaceae) is one of the most toxic and ecologically-threatening weeds in some of the grasslands of north and west China. Bioassay-guided fractionation of root extracts of this plant led to the isolation of eight flavonoids 1-8, whose structures were elucidated by spectroscopic analysis. All compounds obtained, except 7-methoxylneochaejasmin A (4) and (+)-epiafzelechin (5), showed strong phytotoxic activity against Arabidopsis thaliana seedlings. Seedling growth was reduced by neochamaejasmin B (Neochamaejasmine B,1), mesoneochamaejasmin A (2), chamaejasmenin C (3), genkwanol A (6), daphnodorin B (7) and dihydrodaphnodorin B (8) with IC50 values of 6.9, 12.1, 43.2, 74.8, 7.1 and 27.3μg/mL, respectively, and all of these compounds disrupted root development.
Endogenous auxin levels at the root tips of the A. thaliana DR5::GUS transgenic line were largely reduced by compounds 1, 2 and 6-8, and were increased by compound 4. Moreover, the inhibition rate of A. thaliana auxin transport mutants pin2 and aux1-7 by compounds 1-8 were all lower than the wild type (Col-0).
|Natural Product Research & Development, 2014 , 26 (5) :639-44. |
|Nematicidal Activities of Isoneochamaejasmin A and Neochamaejasmin B from the Roots of Stellera chamaejasme L.against Bursaphelenchus xylophilus and Bursaphelenchus mucronatus[Reference: WebLink]|
|Two biflavonoids were isolated from ethanol extract from the roots of Stellera chamaejasme L.,and their chemical structures were identified as isoneochamaejasmin A and neochamaejasmin B(Neochamaejasmine B) by nuclear magnetic resonance spectral data.
METHODS AND RESULTS:
The nematicidal activities of the two compounds were tested by bioassay methods with second-stage juveniles(J2s)of Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. The results showed these two biflavonoids exhibited significantly nematicidal activities against both B. xylophilus and B. mucronatus. Neochamaejasmin B (Neochamaejasmine B)displayed better nematicidal activity than isoneochamaejasmin A against two species nematodes under the same conditions.
Neochamaejasmine B Description
||The roots of Stellera chamaejasme Linn.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Journal of Northwest A & F University, 2008 , 36 (5) :179-184. |
|Further study on relationship between structure and antibacterial activity of neochamaejasmine B[Reference: WebLink]|
| It further studied the relationship between structure and antibacterial activity of Neochamaejasmine B.|
METHODS AND RESULTS:
Four compounds,7″-methoxy Neochamaejasmine B(A2-1),7,7″-dimethoxy Neochamaejasmine B(E3),7,7″,4