ChemFaces is a professional high-purity natural products manufacturer.
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $480.7 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Nat Prod Commun.2014, 9(5):679-82Br J Pharmacol.2016, 173(2):396-410Molecules.2016, 21(6)ARPN Journal of Eng.& Applied Sci...2016...Food Chem.2017, 221:1135-1144Food Quality and Safety2018, 2:213-219Evid Based Complement Alternat Me...2018...Biol Pharm Bull.2018, 41(11):1645-1651
Sci Rep.2018, 8:15059Food Chem.2019, 279:80-87Phytother Res.2019, 33(5):1490-1500Ann Transl Med.2019, 7(23):731Pest Manag Sci.2019, 75(9):2530-2541TCI CO.2019, US20190151257A1Molecules.2020, 25(3):734Front Microbiol.2020, 11:583594.
BMC Complement Med Ther. ...2020...Molecules.2020, 25(15):3353.Chem Biol Interact.2020, 328:109200.Korean J Dent Mater2020, 47(2):63-70.Eur Endod J.2020, 5(1):23-27.Biochem Biophys Res Commun....2020...Research Square2020, doi: 10.21203.
Our products had been exported to the following research institutions and universities, And still growing.
Funda??o Universitária de Dese... (Brazil)Universidade Federal de Pernamb... (Brazil)University of Fribourg (Switzerland)Sanford Burnham Prebys Medical ... (USA)
Uniwersytet Medyczny w ?odzi (Poland)Stanford University (USA)Macau University of Science and... (China)National Chung Hsing University (Taiwan)
Chulalongkorn University (Thailand)Universitas islam negeri Jakarta (Indonesia)Fraunhofer-Institut für Moleku... (Germany)
Related Screening Libraries
||Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. It can reduce seedling growth and disrupt root development, the IC50 value of 6.9 ug/mL . Neochamaejasmine B has antibacterial activity on Gram-positive bacterium and Gram-negative bacterium.
|Phytochemistry. 2014 Oct;106:61-8. |
|Phytotoxic flavonoids from roots of Stellera chamaejasme L. (Thymelaeaceae).[Pubmed: 25096753 ]|
|Allelopathy, the negative effect on plants of chemicals released to the surroundings by a neighboring plant, is an important factor which contributes to the spread of some weeds in plant communities.
METHODS AND RESULTS:
In this field, Stellera chamaejasme L. (Thymelaeaceae) is one of the most toxic and ecologically-threatening weeds in some of the grasslands of north and west China. Bioassay-guided fractionation of root extracts of this plant led to the isolation of eight flavonoids 1-8, whose structures were elucidated by spectroscopic analysis. All compounds obtained, except 7-methoxylneochaejasmin A (4) and (+)-epiafzelechin (5), showed strong phytotoxic activity against Arabidopsis thaliana seedlings. Seedling growth was reduced by neochamaejasmin B (Neochamaejasmine B,1), mesoneochamaejasmin A (2), chamaejasmenin C (3), genkwanol A (6), daphnodorin B (7) and dihydrodaphnodorin B (8) with IC50 values of 6.9, 12.1, 43.2, 74.8, 7.1 and 27.3μg/mL, respectively, and all of these compounds disrupted root development.
Endogenous auxin levels at the root tips of the A. thaliana DR5::GUS transgenic line were largely reduced by compounds 1, 2 and 6-8, and were increased by compound 4. Moreover, the inhibition rate of A. thaliana auxin transport mutants pin2 and aux1-7 by compounds 1-8 were all lower than the wild type (Col-0).
|Natural Product Research & Development, 2014 , 26 (5) :639-44. |
|Nematicidal Activities of Isoneochamaejasmin A and Neochamaejasmin B from the Roots of Stellera chamaejasme L.against Bursaphelenchus xylophilus and Bursaphelenchus mucronatus[Reference: WebLink]|
|Two biflavonoids were isolated from ethanol extract from the roots of Stellera chamaejasme L.,and their chemical structures were identified as isoneochamaejasmin A and neochamaejasmin B(Neochamaejasmine B) by nuclear magnetic resonance spectral data.
METHODS AND RESULTS:
The nematicidal activities of the two compounds were tested by bioassay methods with second-stage juveniles(J2s)of Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. The results showed these two biflavonoids exhibited significantly nematicidal activities against both B. xylophilus and B. mucronatus. Neochamaejasmin B (Neochamaejasmine B)displayed better nematicidal activity than isoneochamaejasmin A against two species nematodes under the same conditions.
Neochamaejasmine B Description
||The roots of Stellera chamaejasme Linn.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Journal of Northwest A & F University, 2008 , 36 (5) :179-184. |
|Further study on relationship between structure and antibacterial activity of neochamaejasmine B[Reference: WebLink]|
| It further studied the relationship between structure and antibacterial activity of Neochamaejasmine B.|
METHODS AND RESULTS:
Four compounds,7″-methoxy Neochamaejasmine B(A2-1),7,7″-dimethoxy Neochamaejasmine B(E3),7,7″,4