ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Univ. of Limpopo2016Food Chem. 2017 Apr 15;Front Plant Sci. 2017 May 8;Braz J Med Biol Res. 2016 Jul 4;49(7).Afr. J. Agric. Res. 27 January 2017
Ind Crops Prod.2014 Dec 1;62:173-178.Phytochem Anal.2013 Sep-Oct.SBRAS2016(12)Kor. J. Pharmacogn.47(1):62-72(2016)J Ethnopharmacol. 2017 Jul 12;
Molecules. 2017 Mar 7;Sci Rep. Jan. 2018Sci Rep. 2017 Jun 12;J. Agric. Food Chem.,2015, 63 (44), 9869–9878
Our products had been exported to the following research institutions and universities, And still growing.
Regional Crop Research Institute (Korea)University of Liège (Belgium)Osmania University (India)Institute of Bioorganic Chemistr... (Poland)
Auburn University (USA)Johannes Gutenberg University Ma... (Germany)Macau University of Science and ... (China)Universidade Federal de Santa Ca... (Brazil)
Medizinische Universit?t Wien (Austria)Melbourne University (Australia)CSIRO - Agriculture Flagship (Australia)
|| Tracheloside significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).
||Estrogen receptor | Progestogen receptor|
|Biosci Biotechnol Biochem. 2006 Nov;70(11):2783-5. |
|An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius.[Pubmed: 17090940]|
|The lignan glycoside, Tracheloside, was isolated from seeds of Carthamus tinctorius (Compositae) as an anti-estrogenic principle against cultured Ishikawa cells by employing a bioassay-linked HPLC-ELSD method. |
METHODS AND RESULTS:
Tracheloside significantly decreased the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).
|Cancer Lett. 2003 Oct 28;200(2):133-9. |
|Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats.[Pubmed: 14568166]|
|Tracheloside, one of the plant lignans which can be extracted from the debris after safflower oil is produced from the seeds of Carthamus tinctorious, is an analogue of another plant lignan, arctiin, the side-chain C-2 of the five-membered ring being changed from a hydrogen to a hydroxyl group. We have already demonstrated that arctiin has chemopreventive effect on mammary carcinogenesis. Therefore, chemopreventive effects of Tracheloside on the initiation or post-initiation period of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female rats were examined. |
METHODS AND RESULTS:
For initiation, female Sprague-Dawley (SD) rats at the 6 weeks of age were given intragastric administrations of 100 mg/kg body weight of PhIP once a week for 8 weeks. The animals were treated with 0.2 or 0.02% Tracheloside during or after this carcinogen exposure. Control rats were fed basal diet with PhIP initiation or 0.2% Tracheloside or basal diet alone without initiation throughout the experimental period. All surviving animals were necropsied at the week 52 of administration. There were no clear treatment-related changes with statistical significance in all parameters for mammary carcinomas measured in this experiment.
These results indicate that Tracheloside may not exert significant effects on PhIP-induced mammary carcinogenesis at least under the present experiment condition.
||The herbs of Trachelospermum jasminoides (Lindl.) Lem.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi: 10.1016/j.phymed.2017.12.030.PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.