|Description:||1. Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals. |
|Source:||The rhizomes of Cyperus rotundus.|
|Solvent:||DMSO, Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||1.4232 mL||7.1159 mL||14.2318 mL||28.4637 mL||35.5796 mL|
|5 mM||0.2846 mL||1.4232 mL||2.8464 mL||5.6927 mL||7.1159 mL|
|10 mM||0.1423 mL||0.7116 mL||1.4232 mL||2.8464 mL||3.558 mL|
|50 mM||0.0285 mL||0.1423 mL||0.2846 mL||0.5693 mL||0.7116 mL|
|100 mM||0.0142 mL||0.0712 mL||0.1423 mL||0.2846 mL||0.3558 mL|
Chem Pharm Bull (Tokyo). 2016;64(1):73-7.
|New Iridoid Glycosides with Antidepressant Activity Isolated from Cyperus rotundus.[Pubmed: 26726748]|
|Based on bioactive screening results, two new iridoid glycosides, named rotunduside G (1) and rotunduside H (2), were isolated from the rhizomes of Cyperus rotundus, together with four known ones, negundoside (3), nishindaside (4), isooleuropein (5) and Neonuezhenide (6). Their structures were elucidated on the basis of spectroscopic methods and from literature values. In mice models of despair, 1 and 2 showed significant antidepressant activity.|
Chem Pharm Bull (Tokyo). 2001 Jun;49(6):780-4.
|Antioxidative glucosides from the fruits of Ligustrum lucidum.[Pubmed: 11411539]|
|The ethanol extract of the fruits of Ligustrum lucidum was shown to have inhibitory effects on the hemolysis of red blood cells induced by 2,2'-azo-bis-(2-amidinopropane) dihydrochloride. Bioassay-guided analysis led to the isolation of ten secoiridoid glucosides. Two of them were new, lucidumosides C and D. Their structures were elucidated by spectroscopic methods. The other eight compounds were identified as oleoside dimethyl ester, ligustroside, oleuropein, nuezhenide, isonuezhenide, Neonuezhenide, lucidumoside A and lucidumoside B. Five compounds, oleoside dimethyl ester, oleuropein, Neonuezhenide, lucidumoside B and lucidumoside C, exhibited strong antioxidant effect against hemolysis of red blood cells induced by free radicals.|