ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
Integr Med Res.2017 Dec;The Japan Society for Analy. Chem.2017 Nov. 8;Front Immunol.2017 Nov 13;BMC Complement Altern Med.2014 Sep 23;14:352.J Nat Prod. 2017 Apr 28;
Plant Cell, (PCTOC)05 November 2016J Drug Target.2016 Feb 24:1-28.Molecules. 2017 Jun 2;Acta Pharmaceutica Sinica B2015 Apr.7.Journal of Agricultural Science2015 Sep 15
SBRAS2016(12)Molecules. 2018 Jan 24;Ajchem JournalJAN. 2014Phytomedicine2015 August 14
Our products had been exported to the following research institutions and universities, And still growing.
China Medical University (Taiwan)Periyar University (India)Charles Sturt University (Denmark)University of Limpopo (South Africa)
Centralised Purchases Unit (CPU)... (India)University of Toulouse (France)Celltrion Chemical Research Inst... (Korea)University of Hawaii Cancer Center (USA)
Hamdard University (India)Medical University of South Caro... (USA)Wroclaw Medical University (Poland)
|| Officinalisinin Ⅰcan effectively reduce the blood glucose and protect nerve injuryin diabetic mice.|
| China Journal of Traditional Chinese Medicine & Pharmacy, 2017 (2) :782-785. |
|Study on hypoglycemic mechanism and central nerve protection of Officinalisinin Ⅰ in Rhizoma Anemarrhenae[Reference: WebLink]|
|To study the hypoglycemic effect of Officinalisinin Ⅰin Rhizoma Anemarrhenae on diabetes, and discuss the hypoglycemic mechanism and protective effect on diabetic nephropathy.|
METHODS AND RESULTS:
Glucose tolerance was measured in model mice induced by oral administration of alloxan.Inhibition of glycosidase activity was tested in vitro.GLP-1 was detected after fasting in diabetic mice.The levels of BDNF and GSH-PX in serum were detected by enzyme-linked immunosorbent assay(ELISA) after 20 days of medication.Officinalisinin I has the functions of lowering blood glucose and significantly improving the glucose tolerance of diabetic mice.In the experiment, the glycosidase inhibitor pathway was eliminated, andby promoting the generation of GLP-1 and BDNF and increasing the activity of GSH-PX Officinalisinin I achieves the hypoglycemic and neuroprotective effect.
Officinalisinin I can effectively reduce the blood glucose and protect nerve injuryin diabetic mice.
Officinalisinin I Description
||The rhizomes of Anemarrhena asphodeloides Bunge
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.