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Rheumone B
Rheumone B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Rheumone B
Price: $318 / 5mg
CAS No.: 2095596-67-9
Catalog No.: CFN91851
Molecular Formula: C22H24O10
Molecular Weight: 448.4 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The aerial parts of Rumex patientia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $318 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Rheumone B Description
Source: The aerial parts of Rumex patientia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2302 mL 11.1508 mL 22.3015 mL 44.603 mL 55.7538 mL
5 mM 0.446 mL 2.2302 mL 4.4603 mL 8.9206 mL 11.1508 mL
10 mM 0.223 mL 1.1151 mL 2.2302 mL 4.4603 mL 5.5754 mL
50 mM 0.0446 mL 0.223 mL 0.446 mL 0.8921 mL 1.1151 mL
100 mM 0.0223 mL 0.1115 mL 0.223 mL 0.446 mL 0.5575 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Natural Product Research, 2017,31(24):2842-2849.
Phenolic constituents from Rheum nobile and their antioxidant activity.[Reference: WebLink]
Although the rhizomes of Rheum nobile Hook. f. et Thoms (Polygonaceae) are widely used in Tibetan medicine, no previous investigations regarding the biological activities and rarely chemical constituents of this plant have been reported.
METHODS AND RESULTS:
As part of an ongoing search for novel bioactive agents, a phytochemical investigation of R. nobile led to the isolation of two new compounds Rheumone B (1) and piceatannol-4'-O-β-D-(6″-O-acetyl)-glucoside (2), together with 15 known compounds by gel filtration over Sephadex LH-20 and preparative HPLC. Their structures were determined by combined spectroscopic methods. Compounds 1-10 were evaluated for their ability to scavenge 2,2-diphenyl-1-picrylhydzyl (DPPH) radical and compounds 7-10 showed relatively strong scavenging abilities with IC50 values from 2.76 μM to 11.80 μM.
CONCLUSIONS:
In conclusion, naphthalene glycosides, stilbene glycosides, flavanols, especially anthraquinones are main chemical constituents of this plant. The ability to scavenge DPPH radical of compound 8 was the highest among compounds 1-10.
Alpha-pinene

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Martynoside

Catalog No: CFN97159
CAS No: 67884-12-2
Price: $338/5mg
Piperlonguminine

Catalog No: CFN91121
CAS No: 5950-12-9
Price: $288/20mg
Kaempferol 3-O-arabinoside

Catalog No: CFN97572
CAS No: 99882-10-7
Price: $338/5mg
Piperine

Catalog No: CFN99919
CAS No: 94-62-2
Price: $30/20mg
Delphinidin chloride

Catalog No: CFN92033
CAS No: 528-53-0
Price: $380/10mg
Myricitrin

Catalog No: CFN99840
CAS No: 17912-87-7
Price: $40/20mg
Gastrodin

Catalog No: CFN99549
CAS No: 62499-27-8
Price: $30/20mg
Kukoamine B

Catalog No: CFN93216
CAS No: 164991-67-7
Price: $268/10mg
Lotusine

Catalog No: CFN93034
CAS No: 6871-67-6
Price: $218/10mg
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