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    S-(5'-Adenosyl)-L-methionine chloride
    S-(5'-Adenosyl)-L-methionine chloride
    CAS No. 24346-00-7 Price $278 / 20mg
    Catalog No.CFN90073Purity>=98%
    Molecular Weight434.9Type of CompoundAlkaloids
    FormulaC15H23ClN6O5SPhysical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $109.0 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • Histone Methyltransferase Inhibitor Library
  • Biological Activity
    Description: Reference standards.
    Targets: Histone Methyltransferase
    In vitro:
    Anal Chim Acta. 2013 Jul 25;788:32-8.
    Amperometric sensing of norepinephrine at picomolar concentrations using screen printed, high surface area mesoporous carbon.[Pubmed: 23845478]

    Norepinephrine (NE) is detected amperometrically using the enzyme Phenylethanolamine N-methyl transferase and cofactor S-(5'-Adenosyl)-L-methionine chloride dihydrochloride with disposable screen printed mesoporous carbon electrodes. The role of internal surface area and pore size of the mesoporous carbon is systematically examined using soft-templated, mesoporous silica-carbon powders with highly microporous walls obtained from etching of the silica to produce powders with surface areas ranging from 671-2339 m(2)g(-1). As the surface area increases, the sensitivity of the biosensor at very low NE concentrations (0-500 pg mL(-1)) in phosphate buffered saline (PBS) increases just as the current signal increases with respect to the NE concentration of 81-1581 μA mL ng(-1) cm(-2) for the mesoporous carbons.
    The best performing electrode provides similar sensitivity in whole rabbit blood in comparison to PBS despite no membrane layer to filter the non-desired reactants; the small (<5 nm) pore size and large internal surface area acts to minimize non-specific events that decrease sensitivity.
    S-(5'-Adenosyl)-L-methionine chloride Description
    Source: From Saccharomyces Ceverisiae.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2994 mL 11.4969 mL 22.9938 mL 45.9876 mL 57.4845 mL
    5 mM 0.4599 mL 2.2994 mL 4.5988 mL 9.1975 mL 11.4969 mL
    10 mM 0.2299 mL 1.1497 mL 2.2994 mL 4.5988 mL 5.7484 mL
    50 mM 0.046 mL 0.2299 mL 0.4599 mL 0.9198 mL 1.1497 mL
    100 mM 0.023 mL 0.115 mL 0.2299 mL 0.4599 mL 0.5748 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.