ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Front Pharmacol. 2017 Sep 29;J Pharm Biomed Anal. 2016 Jun 25;129:50-59. J Chromatogr B Analyt Tec. Bio. Life Sci. 2018 Feb 17;Proc Natl Acad Sci U S A. 2016 Jul 26;J. Int. J. of Food Properties 13 Feb 2017
Int J Mol Sci. 2014 May 13;15(5):8443-57.Int J Biol Macromol. 2018 Feb 12. Experimental Parasitology2015 March 24.Institute of Materia Medica2016 Mar 31, pp.29-35Food Res Int. 2017 Jun;
The Korea Society of Pharmacognosy.2014J. Acta Agr. Scandinavica17 Apr 2017Int. J. of Food Properties08 Feb 2017;Int J Oncol. 2016 Oct;49(4)
Our products had been exported to the following research institutions and universities, And still growing.
Colorado State University (USA)University of Cincinnati (USA)Nanjing University of Chinese Me... (China)Warszawski Uniwersytet Medyczny (Poland)
University of Mysore (India)University of Wollongong (Australia)Cancer Research Initatives Found... (Malaysia)Aveiro University (Portugal)
University of Liège (Belgium)University of Hawaii Cancer Center (USA)Universidade Federal de Santa Ca... (Brazil)
||Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils.|
||Immunology & Inflammation related|
|Planta Med., 2008, 74(9):983-4. |
|Three anti-inflammatory stigmastane steroids from Alchornea floribunda leaves[Reference: WebLink]|
|The anti-inflammatory activities of these compounds were evaluated using in vitro and in vivo animal models. |
METHODS AND RESULTS:
The compounds, 1, 2 and 3 at 5mg/ear inhibited xylene – induced ear edema in mice, with edema inhibitions of 59.9, 51.5 and 51.54% respectively. At 20mg/kg (ip), all the compounds significantly (p<0.05) inhibited acute inflammation induced by subplanta injection of undiluted egg albumen in rats' paw. Compound 1 exhibited a higher anti-inflammatory effect (% edema inhibition=50. 0) than prednisolone (% edema inhibition=48.0) at 3h. 1 and 3 at concentrations of 50 and 100μg/ml significantly (p<0.05) stabilized heat-induced haemolysis of human erythrocytes in vitro, but have no effect on hypotonicity-induced haemolysis. Spectral analysis elucidated the compounds as Stigmastane-3,6-dione (1), stigmastane-22-ene-3,6-dione (2) and 3-hydroxystigmastane-22-ene (3).
These compounds may, in part, account for the anti-inflammatory effect of Alchornea floribunda leaves.
||The roots of Piper nigrum
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J. Agric.Food Chem.,1994, 42(7):1561-2. |
|Boll weevil antifeedants from Eleocharis dulcis Trin.[Reference: WebLink]|
METHODS AND RESULTS:
Six compounds were isolated from the CH2Cl2 extract of eleocharis dulcis Trin. They are hexacosanoic acid, 5 alpha-Stigmastane-3,6-dione, beta-sitosterol, stigmasterol, betulin, and tricin.
5 alpha-Stigmastane-3,6-dione, betulin, and tricin showed antifeedant activity against boll weevils.
|Nat Prod Res. 2013 Aug;27(15):1404-7. |
|Triterpenoid profile of flower and leaf cuticular waxes of heather Calluna vulgaris.[Pubmed: 23148482]|
METHODS AND RESULTS:
Analysis of the main triterpenoid profile of chloroform-soluble cuticular waxes of heather flowers and leaves by GC-MS revealed the following composition: four ketones - α-amyrenone, 4-epi-friedelin, friedelin and taraxerone and seven steroids - campesterol, cholesterol, sitostanol, sitosterol, stigmasterol, stigmasta-3,5-dien-7-one and Stigmastane-3,6-dione. Triterpenoids accounted for 20% and 65% by mass of flower and leaf waxes, respectively, which suggest that heather leaves represent a very promising source of these compounds.
Ursolic acid was the principal triterpenoid in the cuticular wax of both organs, whereas among the neutral triterpenes, friedelin and uvaol were the most abundant in flowers and leaves, respectively.
This report provides the first thorough overview of the triterpenoid composition of cuticular waxes of heather.