ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Acta Pharmaceutica Hungarica...2016...University of Central Lancashire...2017...Aquaculture2017, 481:94-102The Japan Society for Analy. Chem...2017...Industrial Crops and Products...2017...Nutrients.2018, 10(12):E1998Cell.2018, 172(1-2):249-261Phys Chem Chem Phys....2018...
Korean Journal of Medicinal Crop ...2018...Phytomedicine.2018, 38:45-56J Liq Chromatogr R T...2018...Analytical methods2019, 11(6)Nutrients.2019, 11(6):E1380Front Neurosci.2019, 13:1091J Pharm Biomed Anal.2019, 172:268-277Journal of Oil Palm Research...2019...
Korean J of Crop Science2019, 452-458J Clin Med.2019, 8(10):E1664Metabolites.2019, 9(11):E271Biosci. Rep.2020, 10.1024Oxid Med Cell Longev2020, 12Biosci Biotechnol Biochem....2020...Antioxidants (Basel).2020, 9(2): E119
Our products had been exported to the following research institutions and universities, And still growing.
Sapienza University of Rome (Italy)Ateneo de Manila University (Philippines)Chungnam National University (Korea)University of Hull (United Kingdom)
Universidad Industrial de Santa... (Colombia)Colorado State University (USA)Universitas islam negeri Jakarta (Indonesia)University of Oslo (Norway)
Kyushu University (Japan)University of Vigo (Spain)Martin Luther University of Hal... (Germany)
Related Screening Libraries
|| Tenacigenoside A and 11α-O-benzoyl-12β-O-acetyltenacigenin B (TGTB) can significantly increase tumor cell apoptosis on lymphoma bearing mice primarily through down-regulation of BCL2 and BCL-XL, and up-regulation of BID.|
|Leuk Lymphoma. 2015 May 5:1-30. |
|Marsdenia tenacssima and its functional components inhibits proliferation, induces apoptosis of human Burkitt's leukemia/lymphoma cell in vitro and in vivo.[Pubmed: 25942381]|
Burkitt lymphoma is a fast growing non-Hodgkin lymphoma that occurs primarily in young males. The causes of Burkitt lymphoma include chromosome rearrangement and virus infection, but accurate and complete reasons remain to be discovered. The available treatment for Burkitt lymphoma is chemotherapy and radiation therapy. It is a highly aggressive B-cell neoplasm with not all patients cured, in spite of current therapies.
METHODS AND RESULTS:
This study evaluated the effects of traditional Chinese medicine Marsdenia tenacssima (MTE) and its component compound Tenacigenoside A (TGTA) and 11α-O-benzoyl-12β-O-acetyltenacigenin B (TGTB) on human Burkitt lymphoma growth. It was observed that MTE, TGTA or TGTB inhibited cell growth and induced apoptosis of Burkitt lymphoma cells in culture.
In lymphoma bearing NOD/SCID nude mice, both TGTA and TGTB inhibited tumor growth and improved animal survival.
TGTA and TGTB significantly increased tumor cell apoptosis on lymphoma bearing mice, primarily through down-regulation of BCL2 and BCL-XL and up-regulation of BID.
Tenacigenoside A Description
||The herbs of Marsdenia tenacissima
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.