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    Natural Products
    Toddanone
    Toddanone
    Information
    CAS No. 77636-08-9 Price
    Catalog No.CFN92514Purity>=98%
    Molecular Weight290.3Type of CompoundCoumarins
    FormulaC16H18O5Physical DescriptionCryst.
    Download     COA    MSDSSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Coumarins Compound Library
  • Biological Activity
    Description: Standard reference
    In vitro:
    Phytother Res. 2002 May;16(3):281-2.
    Spasmolytic activity of Toddalia asiatica Var. floribunda.[Pubmed: 12164278]

    METHODS AND RESULTS:
    The spasmolytic activity of the aerial parts of Toddalia asiatica var. floribunda (family Rutaceae) was evaluated. The ethanol extract exhibited significant spasmolytic activity and was then partitioned into five fractions. The activity was found to be concentrated only in the hexane and chloroform fractions.
    CONCLUSIONS:
    This activity was shown not to be due to the coumarins, toddalolactone and Toddanone, as was previously thought.
    Huria Journal of the Open University of Tanzania, 2012 , 12 (1).
    Antifeedant activity of twenty six plant extracts and pure compounds from the root bark of Toddalia asiatica (L) (Rutaceae) against the anomalous emperor moth Nudaurelia belina (Saturnidae)[Reference: WebLink]
    The antifeedant activity of petroleum ether (PE) (40-60%) extract of the root bark of T. asiatica and twenty five other plant extracts was investigated against the anomalous emperor moth N. belina.
    METHODS AND RESULTS:
    The petroleum ether extract of stem bark of Albizia anthelmintica, leaves of Cassia occidentalis, Balanites aegyptica, seeds of Cucumis sativaus, root bark of T. asiatica, root bark of Celtis durandii, B. aegyptica and whole plant of Cisus quadrangularis were found to be active against N. belina at a concentration of 1% w/v in a modified leaf disc method. Also, methanol extracts of the root bark of A. muricata and Eucalyptus spp were found to be active against N. belina at a concentration of 1% w/v.
    CONCLUSIONS:
    Three cumarius; dihydrotoddanol, toddanol and toddalactone and the alkaloid dihydrochelerynthrine isolated from the PE extract of the root bark of T. asiatica exhibited antifeedant activity at as low as 0.05% w/v. Toddaculine and Toddanone which were also isolated from the P.E. extract had no activity at 0.05% w/v.
    Toddanone Description
    Source: The roots of Toddalia asiatica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4447 mL 17.2236 mL 34.4471 mL 68.8942 mL 86.1178 mL
    5 mM 0.6889 mL 3.4447 mL 6.8894 mL 13.7788 mL 17.2236 mL
    10 mM 0.3445 mL 1.7224 mL 3.4447 mL 6.8894 mL 8.6118 mL
    50 mM 0.0689 mL 0.3445 mL 0.6889 mL 1.3779 mL 1.7224 mL
    100 mM 0.0344 mL 0.1722 mL 0.3445 mL 0.6889 mL 0.8612 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.