ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Mol Med Rep.2014, 9(5):1653-9J Breast Cancer.2015, 18(2):112-118China Pharmacy2015, 26(27)Inflammation2015, 38(1):445-55University of Limpopo2016, 1-237Onco Targets Ther.2017, 10:3467-3474Org Biomol Chem.2017, 15(31):6483-6492Tropical J. of Pha. Research...2017...
Molecules.2017, 22(3)J Pharm Biomed Anal.2018, 151:32-41Int J Mol Sci.2018, 19(9):E2825Food Chem.2018, 262:78-85Phytother Res.2018, 32(12):2551-2559Journal of Physiology & Pathology...2018...J Sep Sci.2018, 41(7):1682-1690Eur J Pharmacol.2018, 832:96-103
J Chromatogr B Analyt Technol Bio...2019...Molecules.2019, 24(2):329Molecules.2019, 24(23):E4303Cell Chem Biol.2019, 26(1):27-34Pak J Pharm Sci.2019, 32(6)FASEB J.2019, 33(8):9685-9694Phytomedicine.2019, 67:153159
Our products had been exported to the following research institutions and universities, And still growing.
Medizinische Universit?t Wien (Austria)Uniwersytet Jagielloński w Kra... (Poland)Universiti Putra Malaysia(UPM) (Malaysia)Leibniz Institute of Plant Bioc... (Germany)
Shanghai Institute of Organic C... (China)Almansora University (Egypt)Donald Danforth Plant Science C... (USA)CSIRO - Agriculture Flagship (Australia)
Universidade do Porto (Portugal)Ain Shams University (Egypt)Sri Sai Aditya Institute of Pha... (India)
Related Screening Libraries
|| Withaperuvin C may have anti-inflammatory activity with lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells.|
||TNF-α | NF-kB|
|Hawaii J Med Public Health. 2016 Nov;75(11):353-359. |
|The Daniel K. Inouye College of Pharmacy Scripts: Poha Berry (Physalis peruviana) with Potential Anti-inflammatory and Cancer Prevention Activities.[Pubmed: 27920947 ]|
|The edible fruits are commonly known as cape gooseberry or poha in Hawai'i. |
METHODS AND RESULTS:
In part of our study, three new withanolides, physaperuvin G (1), physaperuvins I-J (2-3), along with four known withanolides, namely, 4β-hydroxywithanolide E (4), Withaperuvin C (5), and physalactone (6), coagulin (7) were isolated from the aerial parts of P. peruviana. In addition, two known compounds, phyperunolide F (8), and withanolide S (9), were isolated and identified from the poha berry fruits. The structures and absolute stereochemistry of new compounds from poha were elucidated by several spectroscopy methods: Nuclear Magnetic Resonance (NMR) spectroscopy, X-ray diffraction, and mass spectrometry analyses.
All isolated poha compounds (aerial parts and fruits) were evaluated for their anti-inflammatory activity with lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells, and tumor necrosis factor alpha (TNF-α)-activated nuclear factor-kappa B (NF-κB) with transfected human embryonic kidney cells 293. Most of the isolated natural compounds showed activity with these assays.
Withaperuvin C Description
||The herbs of Physali alkekengi
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.