ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Scientific World Journal....2014...Molecules.2015, 20(11):20014-30Arch Pharm Res.2015, 38(6):1080-9Mol Cells.2015, 38(9):765-72J Agric Food Chem.2015, 63(44):9869-78J Pharm Biomed Anal2016, 118:183-194Food Sci Biotechnol....2016...Chem Biol Interact.2016, 258:59-68
Int. J. of Food Properties...2017...Nat Prod Sci.2018, 24(3):206Academic J of Second Military Med...2018...Biofactors.2018, 44(2):168-179Korean Journal of Pharmacognosy...2018...J Nat Med.2018, 72(3):734-744Molecules.2019, 24(10):E1926Molecules.2019, 24(10):E1930
Molecules.2019, 24(2):E343Pak J Pharm Sci.2019, 32(6):2879-2885Korean Journal of Pharmacognosy...2019...Phytomedicine.2019, 56:48-56Genes Genomics.2020, 10.1007Journal of Chromatography A2020, 460942Plant Growth Regulation...2020...
Our products had been exported to the following research institutions and universities, And still growing.
The Institute of Cancer Research (United Kingdom)Universit?t Basel (Switzerland)Instytut Nawozów Sztucznych w ... (Poland)University of Illinois at Chicago (USA)
St. Jude Children Research Hosp... (USA)Funda??o Universitária de Dese... (Brazil)Worcester Polytechnic Institute (USA)Wageningen University (Netherlands)
University of Hawaii Cancer Center (USA)University of British Columbia (Canada)Universiti Malaysia Pahang (Malaysia)
Related Screening Libraries
|| erythro-Guaiacylglycerol beta-coniferyl ether displays significant inhibitory effects on NO production. |
|J Ethnopharmacol. 2014 May 14;153(3):737-43. |
|Lignans from the stems of Clematis armandii ("Chuan-Mu-Tong") and their anti-neuroinflammatory activities.[Pubmed: 24661966 ]|
METHODS AND RESULTS:
One new and sixteen known lignans were isolated and characterized. The absolute configuration of the new lignan, (7R,8S)-9-acetyl-dehydrodiconiferyl alcohol (1), was elucidated by a combination of 1D/2D NMR techniques and the Electronic Circular Dichroism (ECD) spectroscopy based on the empirical helicity rules.
The anti-neuroinflammatory bioassay showed that compounds 1, (7R,8S)-dehydrodiconiferyl alcohol (2), erythro-guaiacylglycerol-β-coniferyl ether (5), and erythro-Guaiacylglycerol beta-coniferyl ether (6) displayed significant inhibitory effects on NO production. Among them, neolignans 1 and 2 exhibited more potent activities than the positive control (N(G)-monomethyl-L-arginine, L-NMMA), with an IC₅₀ value of 9.3 and 3.9 μM, respectively. Moreover, both 1 and 2 were also found to concentration-dependently suppress the TNF-α release in LPS-stimulated BV-2 cells.
erythro-Guaiacylglycerol beta-coniferyl ether Description
||The herbs of Leucaena leucocephala
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Zhongguo Zhong Yao Za Zhi. 2013 Sep;38(17):2826-31. |
|Chemical constituents from stems of Aquilaria sinensis[Pubmed: 24380305]|
|To study the constituents from the stems of Aquilaria sinensis. |
METHODS AND RESULTS:
The chemical constituents were isolated by various column chromatographic methods.
The structures were identified by spectral analysis including NMR and MS data. Sixteen compounds were isolated and identified as threo-buddlenol C (1), thero-ficusesquilignan A (2), erythro-buddlenol C (3), (+/-) buddlenol D (4), (-) medioresinol (5), (-) pinoresinol (6), 5'-methoxy lariciresinol (7), erythro-Guaiacylglycerol beta-coniferyl ether(8), thero-guaiacylglycerol-beta-coniferyl ether (9), herpetin (10), (+) syringaresinol (11), curuilignan (12), ciwujiatone (13), coniferyl alcohol (14), 3, 4, 5-trimethoxyphenol (15) and cucurbitacin (16).
All the compounds, except for 11-13 were obtained from A. sinensis for the first time.