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  • Science | Nature | Cell | View More
    Bioactive Products
    Inhibitors Compound Library
    A unique collection of 267 Inhibitor natural compounds
    Catalog No: Bb221 Inhibitors Compound Library
    Screening Details
    Size: 1mg/well * 267 Compounds
    2mg/well * 267 Compounds
    Cat. No. Information
    CFN99593 Sanggenone C

    Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. It inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.
    CFN99597 Sennidin A

    Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 uM. Sennidin A in combination with necrosis inducing drugs/therapies may generate synergetic tumoricidal effects on solid malignancies by means of primary debulking and secondary cleansing process. It stimulates glucose incorporation in the phosphatidylinositol 3-kinase (PI3K)- and Akt-dependent in rat adipocytes, but in the IR/IRS1-independent manner.
    CFN99704 Sanggenone D

    Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 cells at > 10 uM; inhibition of nitric oxide production was mediated by suppression of iNOS enzyme induction but not by direct inhibition of iNOS enzyme activity.
    CFN99712 Oroxin A

    Oroxin A is a xanthine oxidase (XO) inhibitor, it exerts its antibreast cancer effects by inducing ER stress-mediated senescence, activating the key stress signaling pathway, and increasing key ER stress genes and expression levels.
    CFN99649 2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol

    (2S,3S,4R,2′R)-2-(2′-hydroxytetracosanoylamino)octadecane-1,3,4-triol shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom at concentration of 100 ug/mL.