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    Natural Products
    15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
    15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
    Information
    CAS No. 1039673-32-9 Price
    Catalog No.CFN99058Purity>=98%
    Molecular Weight304.4 Type of CompoundDiterpenoids
    FormulaC19H28O3Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

    15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
    Product Name 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
    CAS No.: 1039673-32-9
    Catalog No.: CFN99058
    Molecular Formula: C19H28O3
    Molecular Weight: 304.4 g/mol
    Purity: >=98%
    Type of Compound: Diterpenoids
    Physical Desc.: Powder
    Targets: Antifection
    Source: The barks of Pinus yunnanensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1124:323-330
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  • Biological Activity
    Description: 15-Nor-14-oxolabda-8(17),12 E-diene-18-oic acid shows antibacterial (Propionibacterium acnes) and antifungal activities.
    Targets: Antifection
    In vitro:
    Planta Med. 2008 Mar;74(4):449-52.
    Labdane-type diterpenes active against acne from pine cones (Pinus densiflora).[Pubmed: 18484541]

    METHODS AND RESULTS:
    Bioassay-guided extraction and fractionation of the aqueous methanolic extract of the cones of Pinus densiflora (Pinaceae) afforded one new labdane-type diterpene aldehyde, 15-nor-14-oxolabda-8(17),12 E-diene-18-oic acid(15-Nor-14-oxolabda-8(17),12-dien-18-oic acid ), along with eight known diterpenes. Their structures were elucidated using spectroscopic methods as well as by comparison with previously reported data.
    CONCLUSIONS:
    The isolates showed antibacterial (Propionibacterium acnes) and antifungal activities.
    15-Nor-14-oxolabda-8(17),12-dien-18-oic acid Description
    Source: The barks of Pinus yunnanensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.2852 mL 16.4258 mL 32.8515 mL 65.703 mL 82.1288 mL
    5 mM 0.657 mL 3.2852 mL 6.5703 mL 13.1406 mL 16.4258 mL
    10 mM 0.3285 mL 1.6426 mL 3.2852 mL 6.5703 mL 8.2129 mL
    50 mM 0.0657 mL 0.3285 mL 0.657 mL 1.3141 mL 1.6426 mL
    100 mM 0.0329 mL 0.1643 mL 0.3285 mL 0.657 mL 0.8213 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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