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    Natural Products
    3-beta-O-(cis-p-Coumaroyl)maslinic acid
    3-beta-O-(cis-p-Coumaroyl)maslinic acid
    Information
    CAS No. 69297-40-1 Price
    Catalog No.CFN92208Purity>=98%
    Molecular Weight618.9Type of CompoundTriterpenoids
    FormulaC39H54O6Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    3-beta-O-(cis-p-Coumaroyl)maslinic acid

    3-beta-O-(cis-p-Coumaroyl)maslinic acid
    Product Name 3-beta-O-(cis-p-Coumaroyl)maslinic acid
    CAS No.: 69297-40-1
    Catalog No.: CFN92208
    Molecular Formula: C39H54O6
    Molecular Weight: 618.9 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: From Faeces Trogopterpri
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Anticomplementary Compound Library
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  • Biological Activity
    Description: 3-beta-O-(trans-p-Coumaroyl)maslinic acid shows antimicrobial activity on Gram-positive bacteria and yeasts.
    In vitro:
    Planta Medica, 2000, 66(8):768-769.
    Antimicrobial Triterpenoids from Licania heteromorpha.[Reference: WebLink]

    METHODS AND RESULTS:
    Six triterpenoids having a lupane and oleane skeleton were isolated from the leaves and young branches of Licania heteromorpha Bentham var. heteromorpha and were identified as: betulinic acid 1, alphitolic acid 2, 3 beta-O-trans-p-coumaroyl alphitolic acid 3, 3 beta-O-cis-p-coumaroyl alphitolic acid 4, 3 beta-O-trans-p-coumaroyl maslinic acid 5, 3-beta-O-(cis-p-Coumaroyl)maslinic acid 6. The antimicrobial activity of these compounds was evaluated in vitro on clinically isolated microorganisms employing a microdilution method.
    CONCLUSIONS:
    Compounds 2, 3, 5, and 6 showed antimicrobial activity on Gram-positive bacteria and yeasts, whereas none of the six triterpenoids were active against Gram-negative organisms.
    3-beta-O-(cis-p-Coumaroyl)maslinic acid Description
    Source: From Faeces Trogopterpri
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

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    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6158 mL 8.0788 mL 16.1577 mL 32.3154 mL 40.3942 mL
    5 mM 0.3232 mL 1.6158 mL 3.2315 mL 6.4631 mL 8.0788 mL
    10 mM 0.1616 mL 0.8079 mL 1.6158 mL 3.2315 mL 4.0394 mL
    50 mM 0.0323 mL 0.1616 mL 0.3232 mL 0.6463 mL 0.8079 mL
    100 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.3232 mL 0.4039 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chinese Pharmaceutical Journal,2010,45(11):825-828.
    Isolation and identification of 3-O-p-coumaroyloxyl pentacyclic triterpenoids from Lysimachia clethroides Duby.[Reference: WebLink]
    To isolate and identify the 3-O-p-coumaroyloxyl pentacyclic triterpenoids from acetoacetate extract of Lysimachia clethroides Duby, which showed significant cancer chemopreventive activities.
    METHODS AND RESULTS:
    The 3-O-p-coumaroyloxyl pentacyclic triterpenoids were isolated by using silica gel column chromatography, Sephadex LH - 20 chromatography MPLC, and Semi-HPLC. Their structures were elucidated with spectroscopic analysis (NMR, MS and IR). Six 3-O-p-coumaroyloxyl pentacyclic triterpenoids were isolated and identified as 3-beta-O-(cis-p-Coumaroyl)maslinic acid(I), 3-O-trans-p-coumaroyl maslinic acid (II), 3-O-cis-p-coumaroyl-2α-hydroxyursolic acid (III), 3-O-trans-p-coumaroyl-2α-hydroxyursolic acid (IV), 3-O-cis-p-coumaroyl tormentic acid (V) and 3-O-trans-p-coumaroyl tormentic acid (VI).
    CONCLUSIONS:
    All these compounds were obtained from the Lysimachia Genus for the first time.
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