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4-Methoxysalicylic acid
4-Methoxysalicylic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 4-Methoxysalicylic acid
Price: $30 / 20mg
CAS No.: 2237-36-7
Catalog No.: CFN89508
Molecular Formula: C8H8O4
Molecular Weight: 168.14 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The root barks of Periploca sepium.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 4-Methoxysalicylic acid is a natural product from Periploca sepium.
4-Methoxysalicylic acid Description
Source: The root barks of Periploca sepium.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.9474 mL 29.7371 mL 59.4742 mL 118.9485 mL 148.6856 mL
5 mM 1.1895 mL 5.9474 mL 11.8948 mL 23.7897 mL 29.7371 mL
10 mM 0.5947 mL 2.9737 mL 5.9474 mL 11.8948 mL 14.8686 mL
50 mM 0.1189 mL 0.5947 mL 1.1895 mL 2.379 mL 2.9737 mL
100 mM 0.0595 mL 0.2974 mL 0.5947 mL 1.1895 mL 1.4869 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2007 Jul;32(13):1300-2.
Chemical constituents from root barks of Periploca sepium.[Pubmed: 17879730]
To investigate the chemical constituents of the root barks of Periploca sepium.
METHODS AND RESULTS:
Column chromatographic techniques were used to isolate the chemical constituents. NMR and MS methods were employed for their structural elucidation. Eight compounds were isolated and identified as isovanillin (1), vanillin (2), 4-Methoxysalicylic acid (3), (24R)-9, 19-cycloart-25-ene-3beta, 24-diol (4), (24S)-9, 19-cycloart-25-ene-3beta, 24-diol (5), cycloeucalenol (6), beta-amyrin acetate (7) and alpha-amyrin (8).
CONCLUSIONS:
Compounds 1-6 were isolated from this plant for the first time.
CFN96571Trigonosin F1262842-73-8814.94C46H54O13
CFN96075Dihydroobovatin104055-79-0324.4C20H20O4
CFN967223-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone1260173-73-6428.61C27H40O4
CFN99008Macrocarpal N221899-21-4486.6 C28H38O7
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