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5-Hydroxyseselin
5-Hydroxyseselin
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CAS No. 31525-75-4 Price
Catalog No.CFN92512Purity>=98%
Molecular Weight244.2Type of CompoundCoumarins
FormulaC14H12O4Physical DescriptionCryst.
Download COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    5-Hydroxyseselin

    5-Hydroxyseselin
    Product Name 5-Hydroxyseselin
    CAS No.: 31525-75-4
    Catalog No.: CFN92512
    Molecular Formula: C14H12O4
    Molecular Weight: 244.2 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Cryst.
    Source: The roots of Toddalia asiatica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Download: COA    MSDS    SDF
    Similar structural: Comparison (Web)  (SDF)
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    product package
  • Curr Top Med Chem.2020, 20(21):1898-1909.
  • Journal of Apicultural Research2021, 60(1)
  • Chem Biol Interact.2018, 283:59-74
  • Malaysian Journal of Analytical Sciences2022, 26(2):360-369.
  • Journal of Functional Foods2017, 30:30-38
  • QASCF2022, 14(4).
  • Internoational J of Toxicology2020, 10.1177.
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  • Onco Targets Ther.2017, 10:3467-3474
  • Life Sci.2021, 270:119074.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
    Biological Activity
    Description: Reference standards.
    In vitro:
    J Nat Prod. 2005 Jan;68(1):78-82.
    Natural and synthetic 2,2-dimethylpyranocoumarins with antibacterial activity.[Pubmed: 15679322]

    METHODS AND RESULTS:
    A new efficient synthetic approach to the natural coumarins 5-Hydroxyseselin (5), 5-methoxyseselin (3), and (+/-) cis-grandmarin (9) is described as well as the synthesis of some new derivatives in the 5-methoxyseselin series (10-15). The natural coumarins 7-hydroxyalloxanthyletin (6), alloxanthoxyletin (8), and dipetalolactone (7) have also been obtained as secondary products. The type of fusion of the pyrano ring in all cases has been established by 2D NMR spectroscopy.
    CONCLUSIONS:
    The compounds have been studied for their in vitro antibacterial activity, which has been compared with that of some previously synthesized seselin derivatives. The most active compounds were 3, 7, 8, 11, and 14. Some structure-activity relationships are discussed.
    5-Hydroxyseselin Description
    Source: The roots of Toddalia asiatica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.095 mL 20.475 mL 40.95 mL 81.9001 mL 102.3751 mL
    5 mM 0.819 mL 4.095 mL 8.19 mL 16.38 mL 20.475 mL
    10 mM 0.4095 mL 2.0475 mL 4.095 mL 8.19 mL 10.2375 mL
    50 mM 0.0819 mL 0.4095 mL 0.819 mL 1.638 mL 2.0475 mL
    100 mM 0.041 mL 0.2048 mL 0.4095 mL 0.819 mL 1.0238 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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