ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Evid Based Complement Alternat Me...2015...Proc Natl Acad Sci USA....2016...Food Chem.2016, 191:81-90J Nat Med.2017, 71(4):745-756Appl Microbiol Biotechnol....2018...Molecules.2018, 23(7):E1817Korean Journal of Medicinal Crop ...2018...Chem Biol Interact.2018, 290:44-51
Cell Biochem Funct.2018, 36(6):303-311Pharmacol Rep.2018, 70(6):1195-1201Front Immunol.2018, 9:2655J Chromatogr B Analyt Technol Bio...2019...Front Neurosci.2019, 13:1091Nutr Res Pract2019, 13:e45Molecules.2019, 24(11):E2102Molecules.2019, 24(20):3755
Cell Physiol Biochem....2019...Planta Med.2019, 85(3):217-224J of Applied Pharmaceutical Scien...2020...Sci Rep.2020, 10:4495(2020)Drug Des Devel Ther.2020, 14:5189-5204.Biomed Sci Letters.2020, 26:319-326Anticancer Res.2020, 40(10):5529-5538.
Our products had been exported to the following research institutions and universities, And still growing.
University of Ioannina (Greece)Universidade Federal de Santa C... (Brazil)University of Queensland (Australia)Gyeongsang National University (Korea)
Michigan State University (USA)Ateneo de Manila University (Philippines)Universiti Putra Malaysia(UPM) (Malaysia)Chungnam National University (Korea)
Warszawski Uniwersytet Medyczny (Poland)Chulalongkorn University (Thailand)Sanford Burnham Medical Researc... (USA)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Microb Pathog.2019, 131:128-134J Med Food.2020, 23(6):633-640.The Korea Journal of Herbology2020, 35(3):33-45. BMC Pharmacol Toxicol.2018, 19(1):5J Neuroinflammation.2020, 17(1):75.Drug Des Devel Ther.2020, 14:61-71Planta Med.2018, 84(6-07):465-474Molecules.2015, 20(10):19172-88Chemistr of plant2016, 2016021195J. of Med. Plant Research.2013, 90-151
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Alkaloids Compound Library
|J Nat Prod. 2007 Nov;70(11):1783-9. |
|Biologically active aspidofractinine, rhazinilam, akuammiline, and vincorine alkaloids from Kopsia.[Pubmed: 17939738]|
METHODS AND RESULTS:
Eleven new indole alkaloids, in addition to the previously reported rhazinal (1), and 14 other known alkaloids, were obtained from the Malayan Kopsia singapurensis, viz., kopsiloscines A-F (2-7), 16-epikopsinine (8), kopsilongine- N-oxide (9), 16-epiAkuammiline (10), aspidophylline A (11), and vincophylline (12). The structures of these alkaloids were determined using NMR and MS analyses.
Rhazinal (1), rhazinilam (17), and rhazinicine (18) showed appreciable cytotoxicity toward drug-sensitive as well as vincristine-resistant KB cells, while kopsiloscines A (2), B (3), and D (5) and aspidophylline A (11) were found to reverse drug-resistance in drug-resistant KB cells.
||The herbs of Rauvolfia verticillata
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Angew Chem Int Ed Engl. 2015 Jan 7;54(2):400-12. |
|Cascade reactions: a driving force in akuammiline alkaloid total synthesis.[Pubmed: 25346244]|
|The Akuammiline alkaloids are a family of intricate natural products which have received considerable attention from scientists worldwide.
METHODS AND RESULTS:
Despite the fact that many members of this alkaloid class were discovered over 50 years ago, synthetic chemistry has been unable to address their architectures until recently. This minireview provides a brief overview of the rich history of the Akuammiline alkaloids, including their isolation, structural features, biological activity, and proposed biosyntheses. Furthermore, several recently completed total syntheses are discussed in detail. These examples not only serve to highlight modern achievements in alkaloid total synthesis, but also demonstrate how the molecular scaffolds of the
Akuammilines have provided inspiration for the discovery and implementation of innovative cascade reactions for the rapid assembly of complex structures.