ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $480.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Appl. Sci. 2021, 11(10),4666.Nutrients.2019, 11(4):E936Processes2020, 8(12),1540.Sci Rep. 2017, 8207(7)Cells.2021, 10(11):2919. Hum Exp Toxicol.2017, 36(11):1169-1176Chin J Appl. Physiol....2019...Horticulturae2021, 7(1),5.
Food Chem.2019, 276:768-775Planta Med.2019, 85(4):347-355BMC Complement Altern Med....2017...J Nat Med.2017, 71(4):745-756Chemistry of Plant Materials....2016...Molecules.2020, 25(23):5556. Phytomedicine.2016, 23(4):331-9Nat Commun.2021, 12(1):681.
J Pharmaceut Biomed2020, 182:113110Sci Rep.2015, 5:13194ACS Omega.2021, 6(36):23460-23474.Genes (Basel).2021, 12(7):1024.Eur J Pharm Sci.2016, 94:33-45J Ginseng Res.2020, 44(4):611-618.Molecules.2018, 23(9):E2121
More...
Our products had been exported to the following research institutions and universities, And still growing.
Aveiro University (Portugal)Nicolaus Copernicus Uniwersity (Poland)Fraunhofer-Institut für Moleku... (Germany)Tokyo Woman's Christian University (Japan)
Vin?a Institute of Nuclear Scie... (Serbia)Auburn University (USA)National Cancer Center Research... (Japan)Max-Planck-Insitut (Germany)
The Australian National University (Australia)Chiang Mai University (Thailand)Kamphaengphet Rajabhat University (Thailand)
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Alisol A 23-acetate
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Nat Prod.2015, 78(6):1339-4Environ Toxicol.2021, 36(9):1848-1856.Korean J of Medicinal Crop Science2018, 220-226Molecules.2019, 24(2):E343Functional Ecology2020, doi: 10.1111.Korean Journal of Pharmacognosy2019, 50(4):285-290Arch Biochem Biophys.2018, 644:93-99Appl. Sci.2020, 10(20),7374.Horticulturae2021, 7(1),5.JMicrobiol Biotech Food Sci2021, e4289.
Related Screening Libraries
| Description: |
Alisol A 23-acetate may possess therapeutic effects through their modulation of AR, PR, and GR pathways.
|
| Targets: |
Androgen Receptor |
| In vitro: |
| Bioorg Med Chem Lett. 2014 Aug 1;24(15):3626-32. | | Triterpenes from Alisma orientalis act as androgen receptor agonists, progesterone receptor antagonists, and glucocorticoid receptor antagonists.[Pubmed: 24915879] |
METHODS AND RESULTS:
Two triterpenes, alisol M 23-acetate and Alisol A 23-acetate from Alisma orientalis were determined whether they may act as androgen receptor (AR), progesterone receptor (PR), or glucocorticoid receptor (GR) modulators. Indeed, in the transient transfection reporter assays, alisol M 23-acetate and Alisol A 23-acetate transactivated AR in dose-dependent manner, while they transrepressed the transactivation effects exerted by agonist-activated PR and GR. Through molecular modeling docking studies, they were shown to respectively interact with AR, PR, or GR ligand binding pocket fairly well.
CONCLUSIONS:
All these results indicate that alisol M 23-acetate and Alisol A 23-acetate from Alisma orientalis might possess therapeutic effects through their modulation of AR, PR, and GR pathways. |
|
Alisol A 23-acetate Description
| Source: |
The tubers of Alisma plantago-aquatica Linn. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.8771 mL |
9.3853 mL |
18.7705 mL |
37.5411 mL |
46.9263 mL |
| 5 mM |
0.3754 mL |
1.8771 mL |
3.7541 mL |
7.5082 mL |
9.3853 mL |
| 10 mM |
0.1877 mL |
0.9385 mL |
1.8771 mL |
3.7541 mL |
4.6926 mL |
| 50 mM |
0.0375 mL |
0.1877 mL |
0.3754 mL |
0.7508 mL |
0.9385 mL |
| 100 mM |
0.0188 mL |
0.0939 mL |
0.1877 mL |
0.3754 mL |
0.4693 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
