Alisol A 23-acetate | CAS:19865-75-9 | Manufacturer ChemFaces

Alisol A 23-acetate

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Product Name	Alisol A 23-acetate
Price:	$418 / 5mg
CAS No.:	19865-75-9
Catalog No.:	CFN92544
Molecular Formula:	C₃₂H₅₂O₆
Molecular Weight:	532.75 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	White powder
Source:	The tubers of Alisma plantago-aquatica Linn.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $480.7 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Alisol A 23-acetate may possess therapeutic effects through their modulation of AR, PR, and GR pathways.

Targets:

Androgen Receptor

In vitro:

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3626-32.

Triterpenes from Alisma orientalis act as androgen receptor agonists, progesterone receptor antagonists, and glucocorticoid receptor antagonists.[Pubmed: 24915879]

METHODS AND RESULTS:
Two triterpenes, alisol M 23-acetate and Alisol A 23-acetate from Alisma orientalis were determined whether they may act as androgen receptor (AR), progesterone receptor (PR), or glucocorticoid receptor (GR) modulators. Indeed, in the transient transfection reporter assays, alisol M 23-acetate and Alisol A 23-acetate transactivated AR in dose-dependent manner, while they transrepressed the transactivation effects exerted by agonist-activated PR and GR. Through molecular modeling docking studies, they were shown to respectively interact with AR, PR, or GR ligand binding pocket fairly well.
CONCLUSIONS:
All these results indicate that alisol M 23-acetate and Alisol A 23-acetate from Alisma orientalis might possess therapeutic effects through their modulation of AR, PR, and GR pathways.

Alisol A 23-acetate Description

Source:	The tubers of Alisma plantago-aquatica Linn.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antihyperglycemic Compound Library Anti-Atherosclerotic Compound Library Triterpenoids Compound Library Androgen Receptor Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.8771 mL	9.3853 mL	18.7705 mL	37.5411 mL	46.9263 mL
5 mM	0.3754 mL	1.8771 mL	3.7541 mL	7.5082 mL	9.3853 mL
10 mM	0.1877 mL	0.9385 mL	1.8771 mL	3.7541 mL	4.6926 mL
50 mM	0.0375 mL	0.1877 mL	0.3754 mL	0.7508 mL	0.9385 mL
100 mM	0.0188 mL	0.0939 mL	0.1877 mL	0.3754 mL	0.4693 mL

CFN92406	Alisol B	18649-93-9	472.7	C₃₀H₄₈O₄
CFN90158	Alisol B acetate	19865-76-0	514.74	C₃₂H₅₀O₅
CFN99753	Alisol B 23-acetate	26575-95-1	514.8	C₃₂H₅₀O₅
CFN80352	Dehydroalisol B 23-acetate	N/A	512.72	C₃₂H₄₈O₅
CFN92548	Alisol G	155521-46-3	472.7	C₃₀H₄₈O₄
CFN95661	11-Deoxyalisol A	155800-98-9	474.7	C₃₀H₅₀O₄
CFN92542	Alisol A	19885-10-0	490.7	C₃₀H₅₀O₅
CFN92544	Alisol A 23-acetate	19865-75-9	532.75	C₃₂H₅₂O₆
CFN92546	Alisol E 23-acetate	155301-58-9	532.8	C₃₂H₅₂O₆
CFN90198	Alisol A 24-acetate	18674-16-3	532.75	C₃₂H₅₂O₆