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    Natural Products
    Alisol C
    Information
    CAS No. 30489-27-1 Price $388 / 5mg
    Catalog No.CFN92545Purity>=98%
    Molecular Weight486.7Type of CompoundTriterpenoids
    FormulaC30H46O5Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $388 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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  • Biological Activity
    Description: Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxicity.
    In vivo:
    Chinese Traditional & Herbal Drugs, 2014, 45(22):3238-45.
    Chemical constituents from Alisma orientalis extracts with hypoglycemic effect[Reference: WebLink]
    To study the chemical constituents in Alisma orientalis extracts with hypoglycemic effect.
    METHODS AND RESULTS:
    To study the in vivo hypoglycemic effects of A. orientalis extracts, high fat diet (HFD)-induced insulin resistance male C57BL/6J mice were treated with water and ethanol extracts of A. orientalis in diet, and glucose tolerance test was carried out following the intervention. Silica gel, ODS, and preparative HPLC were used to isolate the compounds. Their chemical structures were elucidated on the basis of NMR and MS spectral data. Sixteen compounds were identified as sitosterol (1), palmitic acid (2), heptadecanoic acid (3), eicosanoic acid (4), 11-deoxy-alisol B (5), 23-acetate alisol B (6), 23-acetate Alisol C (7), alisol B (8), 24-acetate alisol A (9), alisol G (10), 24-acetate alisol F (11), alisol L (12), Alisol C (13), alisol F (14), alisol A (15), and 16-oxo-24-acetate alisol A (16), and nine of the triterpenes could improve glucose uptake in HepG2 cells.
    CONCLUSIONS:
    Compounds 3 and 4 are isolated from A. orientalis for the first time. The water and ethanol extracts of A. orientalis could improve glucose tolerance test. Triterpenes may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis.
    Alisol C Description
    Source: The tubers of Alisma plantago-aquatica Linn.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0547 mL 10.2733 mL 20.5465 mL 41.0931 mL 51.3663 mL
    5 mM 0.4109 mL 2.0547 mL 4.1093 mL 8.2186 mL 10.2733 mL
    10 mM 0.2055 mL 1.0273 mL 2.0547 mL 4.1093 mL 5.1366 mL
    50 mM 0.0411 mL 0.2055 mL 0.4109 mL 0.8219 mL 1.0273 mL
    100 mM 0.0205 mL 0.1027 mL 0.2055 mL 0.4109 mL 0.5137 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.