ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $185.3 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Auburn University2015, 1-58J Cell Physiol.2020, 10.1002Nat Prod Commun.2014, 9(5):679-82Separation Science Plus...2022...Exp Mol Med.2020, 52(4):629-642.Food and Fermentation Industries...2018...Anesth Pain Med (Seoul)....2020...Phytochemistry Letters2015, 243-247
Sci Rep. 2017, 12953(7)Anal Bioanal Chem....2020...Journal of Life Science2018, 917-922Srinagarind Medical Journal2019, 34(1)Universidade Estadual Paulista...2017...Appl. Sci.2020, 10(5),1713.Phytochem Anal.2016, 27(5):296-303Antioxidants (Basel)....2021...
Metabolites.2020, 10(11):440.Oncotarget.2016, 8(51):88386-88400Int J Mol Sci.2020, 21(9):3392. Biochem Biophys Res Commun....2018...Chemistry of Natural Compounds...2018...British Jou. Med.&Med. Research...2014...J Ethnopharmacol.2017, 206:73-77
Our products had been exported to the following research institutions and universities, And still growing.
Medical University of South Car... (USA)University of Oslo (Norway)University of Stirling (United Kingdom)University of British Columbia (Canada)
University of Fribourg (Switzerland)Kamphaengphet Rajabhat University (Thailand)Sri Sai Aditya Institute of Pha... (India)University of Bordeaux (France)
Kyoto University (Japan)University of the Basque Country (Spain)University of Pretoria (South Africa)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Kor. J. Pharmacogn.2016, 47(1):62-72J Pharm Biomed Anal.2017, 140:274-280Sci Rep.2019, 9(1):4342J of Food Quality2020, 8851285.Phytomedicine.2020, 153440. Pharm Biol.2017, 55(1):360-366J Formos Med Assoc.2020, S0929-6646(20)30425-3Natural Product Communications2021, 16(9):1-10.J Biochem Mol Toxicol.2020, 34(7):e22489.Front Plant Sci.2020, 11:630.
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Phenols Compound Library
|| Reference standards.|
||The rhizomes of Rheum palmatum
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Planta Med. 2000 Dec;66(8):753-6. |
|Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis.[Pubmed: 11199136 ]|
METHODS AND RESULTS:
Galloyl glucoses and galloyl proanthocyanidins obtained from rhubarb (Rhei Rhizoma, Rheum palmatum L., Polygonaceae); e.g. 1,2,6-tri-O-galloyl-beta-D-glucose (IC50 = 0.63 microM), 1,6-di-O-galloyl-2-O-cinnamoyl-beta-D-glucose (IC50 = 0.58 microM), procyanidin B-2 3,3'-di-O-gallate (IC50 = 0.54 microM), and procyanidin B-5 3,3'-di-O-gallate (IC50 = 0.55 microM), were found to be potent inhibitors of rat squalene epoxidase (SE). The inhibition at submicromolar level was far more potent than that of chemically synthesized substrate analogs.
It was demonstrated for the first time that the cholesterol-lowering effect of rhubarb may be attributed to the potent inhibition activities of SE, a rate-limiting enzyme of cholesterol biogenesis.