ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
J. of Med. Plant Research.2013, 90-151BMC Complement Altern Med.2014, 14:242Int J Mol Med.2015, 35(5):1237-45University of Limpopo2016, 1777J Ethnopharmacol.2016, 192:370-381HortTechnology2016, 26(6):816-819Phytochemistry.2017, 141:162-170Food Chem.2017, 228:301-314
Nutrients.2018, 11(1):E17Mol Pharm.2018, 15(8):3285-3296Korean J Environ Agric....2018...J of the Korean Society of Cosmet...2018...J Chromatogr B Analyt Technol Bio...2019...Int J Mol Sci.2019, 20(14):E3538Phytomedicine.2019, 67:153159Pest Manag Sci.2019, 75(9):2530-2541
Biosci. Rep.2020, 10.1024Food Res Int.2020, 133:109130.Molecules.2020, 25(11):2599. Molecules.2020, 25(18),4089.Cell Rep.2020, 32(11):108158.J Agric Food Chem....2020...Plants (Basel).2020, 9(11):1422.
Our products had been exported to the following research institutions and universities, And still growing.
Anna University (India)The Ohio State University (USA)Research Unit Molecular Epigene... (Germany)University of Maryland (USA)
John Innes Centre (United Kingdom)University of Fribourg (Switzerland)Kitasato University (Japan)The Institute of Cancer Research (United Kingdom)
Vin?a Institute of Nuclear Scie... (Serbia)Institute of Bioorganic Chemist... (Poland)Universidad Industrial de Santa... (Colombia)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Int J Cosmet Sci.2019, 41(1):12-20Biochem Systematics and Ecology2017, 11-18University of Limpopo2016, 1-237Oncotarget.2017, 8(53):90925-90947Processes2020, 8(12),1540.J Vet Sci.2020, 21(3):e39.Food Res Int.2018, 106:909-919The Korea Journal of Herbology2020, 35(3):33-45. BMB Rep.2018, 51(5):249-254Phytomedicine.2020, 79, 153351
Related Screening Libraries
|| Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823.|
|Tetrahedron Letters, 2012, 53(14):1705-9. |
|A pair of tirucallane C27-triterpenoid cyclopentenone epimers from the stem barks of Aphanamixis grandifolia[Reference: WebLink]|
METHODS AND RESULTS:
Two novel tirucallane C27-triterpenoid epimers, aphagranins A (1) and B (2), featuring an unprecedented enolized cyclopentenone presented in the side-chain at C-17, were isolated from the stem barks of Aphanamixis grandifolia.
Extensive spectroscopic analyses helped the establishment of the structures of the two isolates, whose absolute configurations were determined using density functional theory (DFT) calculations of optical rotation, and electronic circular dichroism (ECD).
Remarkable discrepancies in the inhibitory activities against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823) were found for the two epimers: with IC50 less than 10 μM, Aphagranin A exhibited much stronger antiproliferative activity than aphagranin B, showing no such activities with IC50 over 20 μM.
Aphagranin A Description
||The stem barks of Aphanamixis grandifolia.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Magn Reson Chem. 2011 Jul;49(7):450-7. |
|Complete 1H and 13C NMR data assignment of protolimonoids from the stem barks of Aphanamixis grandifolia.[Pubmed: 21590730 ]|
METHODS AND RESULTS:
Seven new protolimonoids, named aphagranins A-G (1-7), along with four known compounds, were isolated from the ethanol extract of the stem barks of Aphanamixis grandifolia.
Structure elucidation and signal assignments were achieved on the basis of spectral and chemical evidences.