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    Natural Products
    Broussonol E
    Information
    CAS No. 363134-28-5 Price
    Catalog No.CFN91978Purity>=98%
    Molecular Weight438.47Type of CompoundFlavonoids
    FormulaC25H26O7Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Broussonol E

    Broussonol E
    Product Name Broussonol E
    CAS No.: 363134-28-5
    Catalog No.: CFN91978
    Molecular Formula: C25H26O7
    Molecular Weight: 438.47 g/mol
    Purity: >=98%
    Type of Compound: Flavonoids
    Physical Desc.: Powder
    Source: The leaves of Broussonetia kazinoki
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Chinese Journal of Hospital Pharmacy2020, 40(7)
  • BMC Microbiol.2019, 19(1):78
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Flavonoids Compound Library
  • Biological Activity
    Description: Broussonol E may show cytotoxic activity against several different cell lines.
    In vitro:
    J Nat Prod. 2001 Sep;64(9):1206-9.
    Five new diprenylated flavonols from the leaves of Broussonetia kazinoki.[Pubmed: 11575957]

    METHODS AND RESULTS:
    Five new diprenylated flavonols, broussonol A (1), broussonol B (2), broussonol C (3), broussonol D (4), and Broussonol E (5), along with two known compounds, were isolated from an ethanolic extract of the leaves of Broussonetia kazinoki.
    CONCLUSIONS:
    Their structures were elucidated by chemical and spectral methods. Cytotoxic activities were evaluated against several different cell lines.
    Broussonol E Description
    Source: The leaves of Broussonetia kazinoki
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2807 mL 11.4033 mL 22.8066 mL 45.6132 mL 57.0164 mL
    5 mM 0.4561 mL 2.2807 mL 4.5613 mL 9.1226 mL 11.4033 mL
    10 mM 0.2281 mL 1.1403 mL 2.2807 mL 4.5613 mL 5.7016 mL
    50 mM 0.0456 mL 0.2281 mL 0.4561 mL 0.9123 mL 1.1403 mL
    100 mM 0.0228 mL 0.114 mL 0.2281 mL 0.4561 mL 0.5702 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chinese Traditional & Herbal Drugs, 2014, 45(24):3520-3523.
    Chemical constituents from Engelhardtia roxburghiana.[Reference: WebLink]
    To study the chemical constituents from the stem bark of Engelhardtia roxburghiana.
    METHODS AND RESULTS:
    The compounds were isolated and purified by various chromatographic techniques and their structures were elucidated by spectral analysis. Ten compounds were obtained and identified as eudesm-4(15)-ene-1β,6α-diol (1), (4S)-4-hydroxy-1-tetralone (2), (-)-regiolone (3), p-hydroxybenzoic acid (4), kaempferol (5), isolicoflavonol (6), broussoflavonol F (7), Broussonol E (8), kaempferol-3-O-α-L-rhamnoside (9), quercetin-3-O-α-L-rhamnoside (10).
    CONCLUSIONS:
    Compounds 1, 4, 6–8 are isolated from the Engelhardtia plants for the first time, and the prenylated flavonoids are firstly reported in this genus.
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