Canophyllal | CAS:14440-40-5 | Manufacturer ChemFaces

Canophyllal

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

3,29-Dibenzoyl karounitriol

Catalog No: CFN90576
CAS No: 873001-54-8
Price: $218/20mg

Amentoflavone

Catalog No: CFN99526
CAS No: 1617-53-4
Price: $40/20mg

Protopine

Catalog No: CFN99399
CAS No: 130-86-9
Price: $50/20mg

1-Acetyl-beta-carboline

Catalog No: CFN92122
CAS No: 50892-83-6
Price: $ / mg

Bornyl acetate

Catalog No: CFN90494
CAS No: 5655-61-8
Price: $30/20mg

Ginsenoside Rg5

Catalog No: CFN92643
CAS No: 186763-78-0
Price: $238/20mg

Decursinol angelate

Catalog No: CFN93173
CAS No: 130848-06-5
Price: $ / mg

Alisol A

Catalog No: CFN92542
CAS No: 19885-10-0
Price: $80/20mg

Sesamin

Catalog No: CFN97034
CAS No: 607-80-7
Price: $40/20mg

Baicalein

Catalog No: CFN98783
CAS No: 491-67-8
Price: $40/20mg

Description:

Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs.

Targets:

Antifection

In vitro:

Chem Pharm Bull (Tokyo). 2008 Mar;56(3):374-7.

Endodesmiadiol, a friedelane triterpenoid, and other antiplasmodial compounds from Endodesmia calophylloides.[Pubmed: 18310952]

METHODS AND RESULTS:
From the ethyl acetate extract of the stem bark of Endodesmia calophylloides (Guttiferae), a novel friedelane triterpenoid named endodesmiadiol (1), as well as the known compounds friedelin (2), canophyllol (3), Canophyllal (4), cerin (5), morelloflavone (6), volkensiflavone (7), 8-deoxygartanin (8), 3 beta-acetoxyoleanolic acid (9) and 1,8-dihydroxy-3-isoprenyloxy-6-methylxanthone (10) have been isolated. The structures of these compounds were established by spectroscopic analysis, and the relative configuration of endodesmiadiol (1) was confirmed by X-ray diffraction. The antiplasmodial activity of the isolated compounds was evaluated against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs.
CONCLUSIONS:
All the compounds were found to be active with IC50 values ranging from 7.2 to 23.6 microM. The IC50 of endodesmiadiol was found to be 11.8 microM.

Canophyllal Description

Source:	The stem bark of Endodesmia calophylloides.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Canophyllal
Price:
CAS No.:	14440-40-5
Catalog No.:	CFN89150
Molecular Formula:	C₃₀H₄₈O₂
Molecular Weight:	440.71 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The stem bark of Endodesmia calophylloides.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antimalaric Compound Library Triterpenoids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.2691 mL	11.3453 mL	22.6907 mL	45.3813 mL	56.7266 mL
5 mM	0.4538 mL	2.2691 mL	4.5381 mL	9.0763 mL	11.3453 mL
10 mM	0.2269 mL	1.1345 mL	2.2691 mL	4.5381 mL	5.6727 mL
50 mM	0.0454 mL	0.2269 mL	0.4538 mL	0.9076 mL	1.1345 mL
100 mM	0.0227 mL	0.1135 mL	0.2269 mL	0.4538 mL	0.5673 mL

CFN98260	Bryonolic acid	24480-45-3	456.7	C₃₀H₄₈O₃
CFN99152	Glycyrrhetinic acid	471-53-4	470.64	C₃₀H₄₆O₄
CFN97747	28-Hydroxy-3-oxoolean-12-en-29-oic acid	381691-22-1	470.69	C₃₀H₄₆O₄
CFN99487	22-Hydroxy-3-oxoolean-12-en-29-oic acid	144629-84-5	470.7	C₃₀H₄₆O₄
CFN97288	3,22-Dihydroxyolean-12-en-29-oic acid	808769-54-2	472.7	C₃₀H₄₈O₄
CFN98018	Triptocallic acid D	201534-09-0	472.7	C₃₀H₄₈O₄
CFN96474	Triptotriterpenic acid A	84108-17-8	472.70	C₃₀H₄₈O₄
CFN97335	Wilforlide A	84104-71-2	454.7	C₃₀H₄₆O₃
CFN97336	Wilforlide A acetate	84104-80-3	496.7	C₃₂H₄₈O₄
CFN96834	Polpunonic acid	33600-93-0	456.71	C₃₀H₄₈O₃