ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin
Citing Use of our Products
How to Order
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Planta Medica International...2022...Microb Pathog.2019, 131:128-134Antioxidants.2022, 11(4), 67.Asian J Beauty Cosmetol...2021...The Journal of Internal Korean Me...2015...American Association for Anatomy...2020...Sci Rep.2017, 7(1):3249Nutrients.2019, 12(1):E40
Molecules.2019, 24(10):E1930Oncol Rep.2016, 35(3):1356-64Metabolites.2019, 9(11):E271Journal of Ginseng Research...2019...Molecules2022, 27(9):2613.Molecules 2022, 27(3),1047.Phytochemistry Letters2021, 43:80-87.Evidence-based Compl.&Alternative...2023...
Phytochemistry Letters2017, 449-455Tokyo Pharmaceutical University...2020...Molecules.2020, 25(18),4089.Chem Pharm Bull (Tokyo)....2019...Front Plant Sci.2022, 13:982771.Chin J Appl. Physiol....2019...Antioxidants (Basel).2021, 10(1):112.
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Our products had been exported to the following research institutions and universities, And still growing.
Uniwersytet Gdański (Poland)Universita' Degli Studi Di Cagl... (Italy)Julius Kühn-Institut (Germany)Universidad de Buenos Aires (Argentina)
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University of Lodz (Poland)Wroclaw Medical University (Poland)MTT Agrifood Research Finland (Finland)
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7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
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Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Am Soc Mass Spectrom.2021, 32(5):1205-1214. Phytomedicine.2019, 55:229-237J Control Release.2021, 336:159-168. Toxicol In Vitro.2023, 86:105521. J Clin Med.2019, 8(10):E1664J Cell Biochem.2018, 119(2):2231-2239J Basic Clin Physiol Pharmacol.2016, 27(1):1-8Molecules.2018, 23(11):E2837J Ethnopharmacol.2016, 192:370-381Pharmacia2022, 69(3): 883-890.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Coumarins Compound Library |
| Description: |
7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells. |
| In vitro: |
| Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1338-41. | | Coumarins from campylotropis hirtella (FRANCH.) SCHINDL. and their inhibitory activity on prostate specific antigen secreted from LNCaP cells.[Pubmed: 18758115] | Campylotropis hirtella (FRANCH.) SCHINDL. was used as a folk medicine for the treatment of benign prostate hyperplasia (BPH) in China.
METHODS AND RESULTS:
In this study, two new coumarins, 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin (1), 6-[(1S,2S)-2-angeloyloxy-1,3-dihydroxy-3-methylbutyl]-7-methoxycoumarin, named angelol M (2), together with eleven known related compounds (3-13) were isolated from this plant under the bioassay guided fractionation.
CONCLUSIONS:
All the compounds showed activity with different levels in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells, using ELISA method. |
|
7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin Description
| Source: |
The roots of Glycyrrhiza uralensis Fisch |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.33 mL |
16.65 mL |
33.3 mL |
66.6001 mL |
83.2501 mL |
| 5 mM |
0.666 mL |
3.33 mL |
6.66 mL |
13.32 mL |
16.65 mL |
| 10 mM |
0.333 mL |
1.665 mL |
3.33 mL |
6.66 mL |
8.325 mL |
| 50 mM |
0.0666 mL |
0.333 mL |
0.666 mL |
1.332 mL |
1.665 mL |
| 100 mM |
0.0333 mL |
0.1665 mL |
0.333 mL |
0.666 mL |
0.8325 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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