Science | Nature | Cell | View More
Natural Products
Catharanthine Tartrate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Catharanthine Tartrate
Price: $100 / 20mg
CAS No.: 2648-21-5
Catalog No.: CFN90318
Molecular Formula: C21H24N2O2.C4H6O6
Molecular Weight: 486.40 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Catharanthus roseus (L.) G.Don
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $42.3 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Chungnam National University (Korea)
  • Utah State University (USA)
  • University of Zurich (Switzerland)
  • Florida International University (USA)
  • Universidad de Antioquia (Colombia)
  • University of South Australia (Australia)
  • Kazusa DNA Research Institute (Japan)
  • University Medical Center Mainz (Germany)
  • Universitas Airlangga (Indonesia)
  • University of Malaya (Malaysia)
  • University of Liège (Belgium)
  • More...
Package
Featured Products
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Guaiol

Catalog No: CFN96326
CAS No: 489-86-1
Price: $ / mg
Erythrodiol

Catalog No: CFN98914
CAS No: 545-48-2
Price: $138/10mg
Isoliquiritin

Catalog No: CFN99155
CAS No: 5041-81-6
Price: $100/20mg
Ginsenoside Ra2

Catalog No: CFN93293
CAS No: 83459-42-1
Price: $218/5mg
Xanthohumol

Catalog No: CFN98958
CAS No: 569-83-5; 6754-58-1
Price: $60/20mg
Luteolin 7-diglucuronide

Catalog No: CFN70468
CAS No: 96400-45-2
Price: $ / mg
Licoricesaponin G2

Catalog No: CFN92915
CAS No: 118441-84-2
Price: $368/20mg
Atractylodin

Catalog No: CFN99535
CAS No: 55290-63-6
Price: $60/20mg
1,3,6-Tri-O-galloylglucose

Catalog No: CFN95043
CAS No: 18483-17-5
Price: $318/10mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Catharanthine Tartrate is an anti-tumor drug. Catharanthine Tartrate binds with DNA in a mode of groove binding, Se(Ⅳ)can inhibit the binding of Catharanthine Tartrate and DNA.
Targets: DNA/RNA Synthesis
In vitro:
CN20071097400
Synthesizing method of vinorelbine tartrate[Reference: WebLink]

METHODS AND RESULTS:
The invention discloses a synthesis method of vinorelbine bitartrate which is characterized in that the method includes following steps: (1) having the Catharanthine Tartrate and vindoline as initial material, reacting with ferric trichloride and hydrochloric acid (2) reacting the above product with the sldium borohydride to get dehydrated vinblastine (3) ring-opening the dehydrated vinblastine by trifluoroacetic anhydride and rearranging to obtain the vinorelbine bitartrate.
CONCLUSIONS:
The method has a low production cost and a high yield and has a good application future.
Catharanthine Tartrate Description
Source: The herbs of Catharanthus roseus (L.) G.Don
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Ganoderenic acid K

Catalog No: CFN95469
CAS No: 942950-94-9
Price: $318/10mg
4-Keto-laurifoline

Catalog No: CFN95594
CAS No: N/A
Price: $318/10mg
Citrusin C

Catalog No: CFN95420
CAS No: 18604-50-7
Price: $318/10mg
Pueroside B

Catalog No: CFN95141
CAS No: 100692-54-4
Price: $288/10mg
3beta-Hydroxyurs-12,18-dien-28-oic...

Catalog No: CFN95461
CAS No: 434942-42-4
Price: $318/5mg
1,3,6-Trihydroxy-2-methylanthraqui...

Catalog No: CFN95095
CAS No: 87686-87-1
Price: $218/10mg
7-(4-Hydroxyphenyl)-1-phenyl-4-hep...

Catalog No: CFN95140
CAS No: 100667-52-5
Price: $318/5mg
Nardoaristolone B

Catalog No: CFN95203
CAS No: 1422517-82-5
Price: $398/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0559 mL 10.2796 mL 20.5592 mL 41.1184 mL 51.398 mL
5 mM 0.4112 mL 2.0559 mL 4.1118 mL 8.2237 mL 10.2796 mL
10 mM 0.2056 mL 1.028 mL 2.0559 mL 4.1118 mL 5.1398 mL
50 mM 0.0411 mL 0.2056 mL 0.4112 mL 0.8224 mL 1.028 mL
100 mM 0.0206 mL 0.1028 mL 0.2056 mL 0.4112 mL 0.514 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
《Journal of Huazhong Normal University(Natural Sciences)》 2011-04
Study on the interaction between catharanthine tartrate and DNA by spectrometric method[Reference: WebLink]

METHODS AND RESULTS:
The interaction of Catharanthine Tartrate and DNA was studied using UV spectrometry,fluorescence spectrometry and fluorescent probe.The results showed that the fluorescence intensity of Catharanthine Tartrate was quenched in the presence of DNA,and this mechanism was judged as static quenching.The binding constant K at 25℃ and 40℃ were calculated as 5.38×104 and 5.85×102,and the binding sites number n as 1.405 and 0.8306.According to the binding constant K at 25℃ and 40℃,the thermodynamic parameters of the reaction of Catharanthine Tartrate and DNA were calculated as follows: ΔHm=-233.77 kJ·mol-1,ΔGm(298 K)=-27.0 kJ·mol-1,ΔSm(298 K)=-693.8 J·K-1·mol-1,and the main binding force between Catharanthine Tartrate and DNA is hydrogen bonding or van der Waals force according to thermodynamic parameters.
CONCLUSIONS:
The UV spectrometry test showed that as the DNA concentration increased,the blue shift of the absorbance peak occured and the absorbance decreased significantly,the results of fluorescence probe test further proved that Catharanthine Tartrate binds with DNA in a mode of groove binding.
《Journal of Hainan Normal University(Natural Science)》 2014-03
Study on the Effect of Se(Ⅳ) on the Interaction Between Catharanthine Tartrate and DNA[Reference: WebLink]

METHODS AND RESULTS:
The effect of Se(Ⅳ)on the interaction between Catharanthine Tartrate and DNA was studied by fluorescence spectrometry, UV spectroscopy and viscosity method. The results showed that the addition of Se(Ⅳ)changed the main binding force of Catharanthine Tartrate and DNA from hydrogen bond and van der Waals force into electrostatic force, and the binding mode from groove binding into electrostatic binding.
CONCLUSIONS:
The change of binding constant and the UV spectroscopy results showed that Se(Ⅳ)can inhibit the binding of Catharanthine Tartrate and DNA.
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Guaiol

Catalog No: CFN96326
CAS No: 489-86-1
Price: $ / mg
Erythrodiol

Catalog No: CFN98914
CAS No: 545-48-2
Price: $138/10mg
Isoliquiritin

Catalog No: CFN99155
CAS No: 5041-81-6
Price: $100/20mg
Ginsenoside Ra2

Catalog No: CFN93293
CAS No: 83459-42-1
Price: $218/5mg
Xanthohumol

Catalog No: CFN98958
CAS No: 569-83-5; 6754-58-1
Price: $60/20mg
Luteolin 7-diglucuronide

Catalog No: CFN70468
CAS No: 96400-45-2
Price: $ / mg
Licoricesaponin G2

Catalog No: CFN92915
CAS No: 118441-84-2
Price: $368/20mg
Atractylodin

Catalog No: CFN99535
CAS No: 55290-63-6
Price: $60/20mg
1,3,6-Tri-O-galloylglucose

Catalog No: CFN95043
CAS No: 18483-17-5
Price: $318/10mg
Tags: buy Catharanthine Tartrate | Catharanthine Tartrate supplier | purchase Catharanthine Tartrate | Catharanthine Tartrate cost | Catharanthine Tartrate manufacturer | order Catharanthine Tartrate | Catharanthine Tartrate distributor