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    Natural Products
    Coumurrayin
    Information
    CAS No. 17245-25-9 Price
    Catalog No.CFN99811Purity>=98%
    Molecular Weight274.3 Type of CompoundCoumarins
    FormulaC16H18O4Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Coumurrayin

    Coumurrayin
    Product Name Coumurrayin
    CAS No.: 17245-25-9
    Catalog No.: CFN99811
    Molecular Formula: C16H18O4
    Molecular Weight: 274.3 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Powder
    Source: The herbs of Murraya paniculata (L.) Jack
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Int J Mol Sci. 2014, 15(5):8443-57
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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    Related Libraries
  • Coumarins Compound Library
  • Biological Activity
    Description: Coumurrayin may have anticoagulant activity.
    In vivo:
    J Egypt Soc Parasitol. 1999;29(1):75-84.
    Rodenticidal activity of two natural coumarines from ether extract of Citrus bergamia.[Pubmed: 12561885]
    The rodenticidal activity, expressed by LD50 values of ether and petroleum ether extracts of Citrus bergamina pulp against two rat species, Rattus norvegicus (Norway rat) and Rattus rattus (roof rat) was evaluated.
    METHODS AND RESULTS:
    Based on LD50 values, ether extract was nearly 1.6 and 1.3 times more toxic to Norway rat and roof rat than ethanol respectively, while pet. ether extract was non toxic to the two rat species. From ether extract, two natural coumarines, Bergapten and Coumurrayin were isolated and tried against the two rat species as anticoagulant rodenticides. Norway rats were more susceptible to both compounds than the roof ones.
    CONCLUSIONS:
    A direct parallel relationship was found between the toxicity and changes in the blood picture.
    Coumurrayin Description
    Source: The herbs of Murraya paniculata (L.) Jack
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6456 mL 18.2282 mL 36.4564 mL 72.9129 mL 91.1411 mL
    5 mM 0.7291 mL 3.6456 mL 7.2913 mL 14.5826 mL 18.2282 mL
    10 mM 0.3646 mL 1.8228 mL 3.6456 mL 7.2913 mL 9.1141 mL
    50 mM 0.0729 mL 0.3646 mL 0.7291 mL 1.4583 mL 1.8228 mL
    100 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.7291 mL 0.9114 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2006 Apr-May;8(3):273-5.
    Chemical constituents of Selinum cryptotaenium.[Pubmed: 16864434]

    METHODS AND RESULTS:
    A new pyranocoumarin, named secryptotaenin A, determined as 3'(S)-angeloyloxy-3',4'-dihydroseselin, was isolated from the roots of Selinum cryptotaenium, along with thirteen known compounds, umbelliferone, osthol, Coumurrayin, (+)-heraclenol, longshengensin A, anomalin, ferulic acid, galactitol, stearic acid, melissic acid, lignoceric acid, beta-sitosterol and daucosterol.
    CONCLUSIONS:
    Their structures were determined on the basis of spectroscopic methods.
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