ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $351.1 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Nat Prod Commun.2014, 9(5):679-82Mol Med Rep.2015, 12(5):7789-95China Pharmacy2015, 26(27)J Basic Clin Physiol Pharmacol....2016...Korean Herb. Med. Inf. 2016, 4(1):35-42Molecular & Cellular Toxicology...2017...Oncotarget.2017, 8(53):90925-90947Neurochem Int.2018, 121:114-124
Phytother Res.2018, 32(12):2551-2559J of Health Science and Alternati...2019...Nutrients.2019, 11(6):E1380Enzyme Microb Technol.2019, 122:64-73Chinese Medicine2019, 14(1)Int J Mol Sci.2019, 20(14):E3538Phytomedicine.2019, 55:229-237Ann Transl Med.2019, 7(23):731
J Cell Physiol.2020, 10.1002Int J Pharmacol2020, 16:1-9Evid-Based Compl Alt2020, 7202519:13Biosci Biotechnol Biochem....2020...Food Addit Contam Part A Chem Ana...2020...Applied Biological Chemistry...2020...Inflammation.2021, doi: 10.1007
Our products had been exported to the following research institutions and universities, And still growing.
Chang Gung University (Taiwan)Pennsylvania State University (USA)University of Auckland (New Zealand)Sri Ramachandra University (India)
University of Parma (Italy)Chungnam National University (Korea)Uniwersytet Medyczny w ?odzi (Poland)Universitas Airlangga (Indonesia)
Centralised Purchases Unit (CPU... (India)Complutense University of Madrid (Spain)Universidad de Buenos Aires (Argentina)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Nat Med.2018, 72(3):734-744Front Microbiol.2019, 10:2806Front Pharmacol.2019, 10:1025Process Biochemistry2019, 87:213-220Oxid Med Cell Longev2019, 9056845:13Biochem Systematics and Ecology2017, 11-18Medicina (Kaunas).2020, 56(12):685.Pharmacogn Mag.2015, 11:S585-91J Asian Nat Prod Res.2019, 5:1-17Int J Oncol.2016, 49(4):1497-504
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Lignans Compound Library
|| Reference standards.|
|Pharm Biol. 2013 Sep;51(9):1204-7. |
|Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens.[Pubmed: 23883077 ]|
|The diethyl ether extract of the stems of Schisandra pubescens Hemsl. et Wils. (Schisandraceae) was found to exhibit cytotoxic activity in vitro. However, investigations of the bioactive constituents of this plant have been very limited.
Elucidation of the cytotoxic constituents of S. pubescens was performed.
METHODS AND RESULTS:
Repeated silica gel column chromatography and preparative TLC were used for the chemical investigation of the diethyl ether extract of S. pubescens stems. All isolates were evaluated for their in vitro cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines.Nine known compounds were obtained, including four lignans, Epischisandrone (1), tigloylgomisin P (2), cagayanone (3) and (-)-gomisin L₂ (4), together with five triterpenoids, micranoic acid B (5), lancifodilactone H (6), coccinic acid (7), schisanlactone B (8) and anwuweizonic acid (9). Compounds 2-6 and 8 showed moderate to marginal cytotoxicity, with GI₅₀ values of 11.83-35.65 μM.
The isolation of 1-9 from S. pubescens and the cytotoxicities of 3-6 are first reported. Compounds 2-6 and 8 could be the active principles responsible for the anticancer effects of S. pubescens.
||The fruits of Schisandra sphenanthera
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Chem Pharm Bull (Tokyo). 2009 Apr;57(4):405-7. |
|Two new lignans from Schisandra henryi.[Pubmed: 19336937]|
METHODS AND RESULTS:
Two new lignans, henricines A (1) and B (2), were isolated along with the eight known lignans, ganshisandrine (3), wulignan A(2) (4), epiwulignan A(1) (5), deoxyschisandrin (6), wulignan A(1) (7), Epischisandrone (8), schisantherin A (9), and schisandrol A (10), from the stems of Schisandra henryi.
The structures of the new compounds were elucidated based on the spectral analysis, including 1D and 2D NMR experiments.