Garjasmin | CAS:144868-43-9 | Manufacturer ChemFaces

Garjasmin

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Description:

Garjasmine exhibits weak cytotoxic activity against KB and MCF-7 cell lines.

In vitro:

Fitoterapia,2016,113:97-101.

Two new bioactive iridoids from Rothmannia wittii.[Pubmed: 27431771 ]

METHODS AND RESULTS:
The first reported study of the isolation and identification of compounds from the bark and fruit of Rothmannia wittii yielded two new iridoids, 6β-hydroxy-10-O-acetylgenipin (1) and 10-O-acetylmacrophyllide (2) together with six known iridoids; 6β-hydroxygenipin (3), genipin (4), Garjasmine (5), cerbinal (6), and mixture of β-gardiol (7) and α-gardiol (8); benzoic acid (9); vanillic acid (10); and stigmasterol (11). Their structures were elucidated by spectroscopic methods.
CONCLUSIONS:
Iridoid 1 showed antimycobacterial activity against Mycobacterium tuberculosis with a MIC value of 12.50μg/mL. Iridoid 2 showed cytotoxicity against the NCI-H187 cancer cell line with an IC50 value of 6.82μg/mL. In addition, 2 and 5 exhibited weak cytotoxic activity against KB and MCF-7 cell lines, while 4 was active against the NCI-H187 cancer cell line.

Garjasmin Description

Source:	The herbs of Nauclea officinalis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Garjasmin
Price:
CAS No.:	144868-43-9
Catalog No.:	CFN99492
Molecular Formula:	C₁₁H₁₂O₅
Molecular Weight:	224.2 g/mol
Purity:	>=98%
Type of Compound:	Iridoids
Physical Desc.:	Powder
Source:	The herbs of Nauclea officinalis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Iridoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.4603 mL	22.3015 mL	44.603 mL	89.2061 mL	111.5076 mL
5 mM	0.8921 mL	4.4603 mL	8.9206 mL	17.8412 mL	22.3015 mL
10 mM	0.446 mL	2.2302 mL	4.4603 mL	8.9206 mL	11.1508 mL
50 mM	0.0892 mL	0.446 mL	0.8921 mL	1.7841 mL	2.2302 mL
100 mM	0.0446 mL	0.223 mL	0.446 mL	0.8921 mL	1.1151 mL

CFN90237	Gardenoside	24512-62-7	404.37	C₁₇H₂₄O₁₁
CFN96355	Splendoside	81969-41-7	406.4	C₁₇H₂₆O₁₁
CFN90753	Dipsanoside A	889678-62-0	1475.4	C₆₆H₉₀O₃₇
CFN90754	Dipsanoside B	889678-64-2	1475.4	C₆₆H₉₀O₃₇
CFN89296	7-Deoxy-10-hydroxyloganetin	76267-48-6	228.24	C₁₁H₁₆O₅
CFN91452	Deoxyloganin	26660-57-1	374.4	C₁₇H₂₆O₉
CFN99858	Loganin	18524-94-2	390.4	C₁₇H₂₆O₁₀
CFN95478	8-Epiloganin	79172-04-6	390.4	C₁₇H₂₆O₁₀
CFN95452	10-Carboxyloganin	182172-02-7	420.4	C₁₇H₂₄O₁₂
CFN98160	Cornin	548-37-8	388.37	C₁₇H₂₄O₁₀