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    Natural Products
    Gnetin D
    Information
    CAS No. 84870-53-1 Price $468 / 5mg
    Catalog No.CFN92423Purity>=98%
    Molecular Weight470.5Type of CompoundPhenols
    FormulaC28H22O7Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Tel: (0086)-27-84237683
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $468 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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  • Package
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    Gnetin D

    Gnetin D
    Product Name Gnetin D
    CAS No.: 84870-53-1
    Catalog No.: CFN92423
    Molecular Formula: C28H22O7
    Molecular Weight: 470.5 g/mol
    Purity: >=98%
    Type of Compound: Phenols
    Physical Desc.: Powder
    Targets: Influenza virus
    Source: The herbs of Gnetum cleistostachynm
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $468 / 5mg
    Inquire / Order: manager@chemfaces.com
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    Fax: +86-27-84254680

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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
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  • Biological Activity
    Description: Gnetin D exhibits significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99  ug/mL.
    Targets: Influenza virus
    In vitro:
    Planta Med. 2010 Nov;76(16):1874-6.
    In vitro anti-influenza viral activities of stilbenoids from the lianas of Gnetum pendulum.[Pubmed: 20539973 ]
    The anti-influenza viral activities of six stilbenoids from the lianas of Gnetum pendulum C. Y. Cheng were evaluated with two different assays, neuraminidase (NA) activity assay and cytopathic effect (CPE) reduction assay.
    METHODS AND RESULTS:
    The NA assay results showed that all six stilbenoids exerted an NA inhibitory effect, while the CPE assay indicated that among them, isorhapontigenin (2), gnetupendin B (3), shegansu B (4), and Gnetin D 6) exhibit significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 µg/mL in comparison to the positive controls oseltamivir acid and ribavirin whose IC(50) values were 0.040 and 5.54 µg/mL, respectively.
    Gnetin D Description
    Source: The herbs of Gnetum cleistostachynm
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1254 mL 10.627 mL 21.254 mL 42.508 mL 53.135 mL
    5 mM 0.4251 mL 2.1254 mL 4.2508 mL 8.5016 mL 10.627 mL
    10 mM 0.2125 mL 1.0627 mL 2.1254 mL 4.2508 mL 5.3135 mL
    50 mM 0.0425 mL 0.2125 mL 0.4251 mL 0.8502 mL 1.0627 mL
    100 mM 0.0213 mL 0.1063 mL 0.2125 mL 0.4251 mL 0.5313 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Phytochemistry. 2012 Feb;74:166-72.
    Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi.[Pubmed: 22137037]
    A phytochemical study of the ethyl acetate extract of the roots and adventitious roots of Spirotropis longifolia, a monodominant tree species of the Guianan rainforest, has allowed the isolation of three compounds: 2-hydroxy-8,9-methylenedioxy-2',2'-dimethylpyrano-[5',6':4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin A), 2-hydroxy-8,9-methylenedioxy-2',2'-dimethyl-3',4'-dihydropyrano-[5',6':4,3]-6a-prenyl-[6aS,11aS]-pterocarpan (spirotropin B), and 5,7-dihydroxy-6,8-diprenyl-2'''',2''''-dimethylpyrano[5'''',6'''': 3',4']-isoflavone (spirotropone). In addition, 10 known compounds, trans-oxyresveratrol, trans-resveratrol, piceatannol, daidzein, genistein, isoprunetin, lupeol, latifolol, Gnetin D and gnetin E, were also isolated.
    METHODS AND RESULTS:
    These compounds were evaluated for their antifungal activity and their cytotoxicity, and their structures were established by 1D and 2D NMR, HRMS, CD and optical rotation measurements.
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