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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $128.8 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Korean Journal of Pharmacognosy....2020...Appl. Sci. 2021, 11(22),10569Phytomedicine.2022, 99:154025.Front Pharmacol.2021, 12:744624.J Appl Microbiol.2022, 132(2):949-963.National Academy Science Letters...2023...J Clin Med.2022, 11(13):3662.Molecules.2019, 24(9):E1719
Molecules.2021, 26(13):4081.J Nat Med.2017, 71(2):457-462Int J Mol Sci.2020, 21(19):7209.J Ethnopharmacol.2019, 236:31-41Front Cell Dev Biol.2021, 9:764263.Exp Parasitol.2018, 194:67-78Appl. Sci.2020, 10(20),7374.Applied Physics B2021, 127(92).
Int J Biol Macromol.2019, 126:653-661Biomed Chromatogr.2016, 30(10):1573-81Int J Mol Sci.2022, 23(5):2796. Medicinal Chemistry Research ...2021...J Mol Recognit.2020, 33(2):e2819Evid Based Complement Alternat Me...2021...Chem Biol Interact.2018, 283:59-74
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Our products had been exported to the following research institutions and universities, And still growing.
Almansora University (Egypt)Universidade da Beira Interior (Germany)University of Madras (India)Shanghai University of TCM (China)
Instytut Nawozów Sztucznych w ... (Poland)University of Wisconsin-Madison (USA)Instituto de Investigaciones Ag... (Chile)Ateneo de Manila University (Philippines)
Medical University of South Car... (USA)University of Wuerzburg (Germany)Universidad de Antioquia (Colombia)
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Hederacoside D
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manager@chemfaces.com
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service@chemfaces.com
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FEBS Lett.2021, 595(20):2608-2615. Analytical sci. & Tech2020, 33(5):224-231Front Pharmacol.2022, 13:972825.Separations2021, 8(7),90.Turkish Journal of Pharmaceutical Sciences2022, DOI: 10.4274J. Traditional Thai Medical Res. 2022,8(1):1-14.J Nutr Biochem.2022, 107:109064. PLoS One.2022, 17(4):e0267007. Pak J Pharm Sci.2019, 32(6)Sustainable Chemistry & Pharmacy2022, 30:100883.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
Hederacoside D is a narural product from Hedera nepalensis. |
Hederacoside D Description
| Source: |
The herbs of Hedera nepalensis. |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
0.9306 mL |
4.6531 mL |
9.3061 mL |
18.6123 mL |
23.2653 mL |
| 5 mM |
0.1861 mL |
0.9306 mL |
1.8612 mL |
3.7225 mL |
4.6531 mL |
| 10 mM |
0.0931 mL |
0.4653 mL |
0.9306 mL |
1.8612 mL |
2.3265 mL |
| 50 mM |
0.0186 mL |
0.0931 mL |
0.1861 mL |
0.3722 mL |
0.4653 mL |
| 100 mM |
0.0093 mL |
0.0465 mL |
0.0931 mL |
0.1861 mL |
0.2327 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| J Sep Sci. 2016 Sep;39(17):3292-301. | | Pharmacokinetic parameters of three active ingredients hederacoside C, hederacoside D, and ɑ-hederin in Hedera helix in rats.[Pubmed: 27377040 ] | In Hedera helix hederacoside C, Hederacoside D, and ɑ-hederin are three major bioactive saponins and play pivotal roles in the overall biological activity.
METHODS AND RESULTS:
In this study, a specific and sensitive ultra-high performance liquid chromatography with tandem mass spectrometry method has been developed and validated for the quantification of three major bioactive saponins in rat plasma. Chromatographic separation was performed on a reversed-phase Thermo Hypersil GOLD C18 column (2.1 mm × 50 mm, 1.9 μm) using a gradient mobile phase system of acetonitrile-water containing 0.1% formic acid. The assay was successfully applied to study the pharmacokinetic behavior of the three analytes in rats after oral and intravenous administration of a mixture of saponins (hederacoside C, Hederacoside D, and ɑ-hederin). Further research was performed to compare the pharmacokinetic behavior of the three analytes after the oral administration of a mixture of saponins and an extract of saponins from Hedera helix, and results showed that double peaks were evident on concentration-time profile for each of the three saponins.
CONCLUSIONS:
The difference in the pharmacokinetic characteristics of three saponins between a mixture of saponins and an extract of saponins from Hedera helix was found in rat, which would be beneficial for the preclinical research and clinical use of Hedera helix. |
|
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