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    Natural Products
    Hederacoside D
    Information
    CAS No. 760961-03-3 Price $218 / 20mg
    Catalog No.CFN90184Purity>=98%
    Molecular Weight1074.56Type of CompoundTriterpenoids
    FormulaC53H86O22Physical DescriptionWhite powder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $128.8 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Hederacoside D

    Hederacoside D
    Product Name Hederacoside D
    CAS No.: 760961-03-3
    Catalog No.: CFN90184
    Molecular Formula: C53H86O22
    Molecular Weight: 1074.56 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: White powder
    Source: The herbs of Hedera nepalensis.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $218 / 20mg
    Inquire / Order: manager@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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    Description: Hederacoside D is a narural product from Hedera nepalensis.
    Hederacoside D Description
    Source: The herbs of Hedera nepalensis.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.9306 mL 4.6531 mL 9.3061 mL 18.6123 mL 23.2653 mL
    5 mM 0.1861 mL 0.9306 mL 1.8612 mL 3.7225 mL 4.6531 mL
    10 mM 0.0931 mL 0.4653 mL 0.9306 mL 1.8612 mL 2.3265 mL
    50 mM 0.0186 mL 0.0931 mL 0.1861 mL 0.3722 mL 0.4653 mL
    100 mM 0.0093 mL 0.0465 mL 0.0931 mL 0.1861 mL 0.2327 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Sep Sci. 2016 Sep;39(17):3292-301.
    Pharmacokinetic parameters of three active ingredients hederacoside C, hederacoside D, and ɑ-hederin in Hedera helix in rats.[Pubmed: 27377040 ]
    In Hedera helix hederacoside C, Hederacoside D, and ɑ-hederin are three major bioactive saponins and play pivotal roles in the overall biological activity.
    METHODS AND RESULTS:
    In this study, a specific and sensitive ultra-high performance liquid chromatography with tandem mass spectrometry method has been developed and validated for the quantification of three major bioactive saponins in rat plasma. Chromatographic separation was performed on a reversed-phase Thermo Hypersil GOLD C18 column (2.1 mm × 50 mm, 1.9 μm) using a gradient mobile phase system of acetonitrile-water containing 0.1% formic acid. The assay was successfully applied to study the pharmacokinetic behavior of the three analytes in rats after oral and intravenous administration of a mixture of saponins (hederacoside C, Hederacoside D, and ɑ-hederin). Further research was performed to compare the pharmacokinetic behavior of the three analytes after the oral administration of a mixture of saponins and an extract of saponins from Hedera helix, and results showed that double peaks were evident on concentration-time profile for each of the three saponins.
    CONCLUSIONS:
    The difference in the pharmacokinetic characteristics of three saponins between a mixture of saponins and an extract of saponins from Hedera helix was found in rat, which would be beneficial for the preclinical research and clinical use of Hedera helix.
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