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    Natural Products
    Isocarapanaubine
    Information
    CAS No. 17391-09-2 Price
    Catalog No.CFN99819Purity>=98%
    Molecular Weight428.5 Type of CompoundAlkaloids
    FormulaC23H28N2O6Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Isocarapanaubine

    Isocarapanaubine
    Product Name Isocarapanaubine
    CAS No.: 17391-09-2
    Catalog No.: CFN99819
    Molecular Formula: C23H28N2O6
    Molecular Weight: 428.5 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The herbs of Rauvolfia verticillata (Lour.) Baill.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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    Description: Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.
    Isocarapanaubine Description
    Source: The herbs of Rauvolfia verticillata (Lour.) Baill.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3337 mL 11.6686 mL 23.3372 mL 46.6744 mL 58.3431 mL
    5 mM 0.4667 mL 2.3337 mL 4.6674 mL 9.3349 mL 11.6686 mL
    10 mM 0.2334 mL 1.1669 mL 2.3337 mL 4.6674 mL 5.8343 mL
    50 mM 0.0467 mL 0.2334 mL 0.4667 mL 0.9335 mL 1.1669 mL
    100 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.4667 mL 0.5834 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chem Pharm Bull (Tokyo). 2010 Aug;58(8):1085-7.
    Oppositinines A and B: new vasorelaxant beta-carboline alkaloids from Neisosperma oppositifolia.[Pubmed: 20686264]

    METHODS AND RESULTS:
    A phytochemical study on the bark of Neisosperma oppositifolia (Apocynaceae) yielded two new beta-carboline indole alkaloids, oppositinines A (1) and B (2), together with five known alkaloids, isoreserpiline, Isocarapanaubine, vobasine, 10-methoxydihydrocorynantheol-N-oxide, and ochropposinine oxindole. Structural elucidation of 1 and 2 was performed using 2D NMR methods.
    CONCLUSIONS:
    Oppositinines A (1) and B (2) showed potent vasorelaxant effects on the rat aorta.
    Natural Medicines,1999, 53(5):272.
    Cytotoxic Alkaloids from the Barks of Ochrosia elliptica(Natural Medicine Note)[Reference: WebLink]

    METHODS AND RESULTS:
    Reserpiline (3) and Isocarapanaubine (4), along with ellipticine (1) and 9-methoxyellipticine (2), were isolated as the cytotoxic constituents from the barks of Ochrosia elliptica.
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