ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $32.8 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Agronomy2020, 10(10),1489J Biochem Mol Toxicol....2020...Int J Mol Sci.2021, 22(14):7324.J Food Biochem.2020, 44(6):e13198. Molecules.2019, 24(7):E1290Biomedicines.2020, 8(11):486.Pharmacognosy Journal...2019...Biomed Chromatogr.2019, 8:e4774
Pathogens.2018, 7(3):E62Biomolecules2021, 11(10),1513.Int J Mol Sci.2021, 22(17):9400. Turkish Journal of Pharmaceutical...2022...Mol Pharmacol.2021, 99(2):163-174.J Breast Cancer.2015, 18(2):112-118Evid Based Complement Alternat Me...2018...Front Pharmacol.2020, 11:683.
Front Pharmacol.2021, 12:744624.Acta Edulis Fungi2020, 27(02):63-76.BMC Plant Biol.2020, 20(1):214. Chinese Medicine2019, 14(1)Integr Med Res.2017, 6(4):395-403Pharm Biol.2017, 55(1):360-366Molecules.2021, 26(23):7390.
Our products had been exported to the following research institutions and universities, And still growing.
Aarhus University (Denmark)Texas A&M University (USA)Instituto Politécnico de Bragan?a (Portugal)Harvard University (USA)
Mahidol University (Thailand)Indian Institute of Science (India)Universiti Kebangsaan Malaysia (Malaysia)Korea Intitute of Science and T... (Korea)
University of Cincinnati (USA)Aveiro University (Portugal)University of Bordeaux (France)
Isochlorogenic acid B
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Chem Biol Interact.2016, 258:59-68Cancer Manag Res.2019, 11:483-500Pol J Microbiol.2021, 70(1):117-130.J Ethnopharmacol.2020, 269:113752. Food Analytical Methods2017, 10:3225-3234Molecules.2017, 22(2)Front Microbiol.2019, 10:2806Biomol Ther (Seoul).2019, 10.4062Foods.2021, 10(11):2627. Journal of Functional Foods2017, 30:30-38
Related Screening Libraries
||Isochlorogenic acid B has antioxidant activity, it is a potential PDE-5 inhibitor. |
Isochlorogenic acid B Description
||The flowerbud of Lonicera japonica Thunb.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Biomol Struct Dyn. 2010 Apr;27(5):627-40. |
|Virtual screening and drug design for PDE-5 receptor from traditional Chinese medicine database.[Pubmed: 20085380]|
|From docking analyses, Isochlorogenic acid B was identified as the most potential inhibitory compound. De novo evolution designed 47 derivatives. Of the 47 derivatives, seven were able to map into the pharmacophore model, and these seven compounds were suggested to be the most promising leads for inhibiting PDE-5. An analysis of the hydrogen bond interactions formed between the docked ligands and PDE-5 identified ASN662, SER663 and GLN817 as the most frequently interacting residues. A total of eight novel leading compounds were identified to have favorable interaction with PDE-5. These compounds all had hydrogen bond interactions with three key residues that could be further investigated for understanding of PDE-5 and ligands interaction.|
|PLoS One. 2014 Sep 2;9(9):e106254. |
|The activity-integrated method for quality assessment of reduning injection by on-line DPPH-CE-DAD.[Pubmed: 25181475]|
|A sensitive on-line DPPH-CE-DAD method was developed and validated for both screening and determining the concentration of seven antioxidants of Reduning injection. The pH and concentrations of buffer solution, SDS, β-CD and organic modifier were studied for the detection of DPPH and seven antioxidants. By on-line mixing DPPH and sample solution, a DPPH-CE method for testing the antioxidant activity of the complex matrix was successfully established and used to screen the antioxidant components of Reduning injection. Then, antioxidant components including caffeic acid, isochlorogenic acid A, Isochlorogenic acid B, isochlorogenic acid C, chlorogenic acid, neochlorogenic acid and cryptochlorogenic acid were quantified by the newly established CE-DAD method.|