Isoescin IB | CAS:219944-46-4 | Manufacturer ChemFaces

Isoescin IB

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $250.7 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Isoescin IB Description

Source:	The herbs of Aesculus hippocastanum L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Adv Pharm Bull. 2015 Nov;5(4):587-91.

Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography.[Pubmed: 26819933 ]

To separate and quantify four major saponins in the extracts of the skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum L.) using ultrasonic solvent extraction followed by a high performance liquid chromatography-diode array detector (HPLC-DAD) with positive confirmation by thin layer chromatography (TLC).
METHODS AND RESULTS:
The saponins: escin Ia, escin Ib, isoescin Ia and Isoescin IB were extracted using ultrasonic extraction method. The optimized extraction conditions were: 70% methanol as extraction solvent, 80 °C as extraction temperature, and the extraction time was achieved in 4 hours. The HPLC conditions used: Zorbax SB-ODS-(150 mm × 2.1 mm, 3 μm) column, acetonitrile and 0.10% phosphoric acid solution (39:61 v/v) as mobile phase, flow rate was 0.5 mL min(-1) at 210 nm and 230 nm detection. The injection volume was 10 μL, and the separation was carried out isothermally at 30 °C in a heated chamber. The results indicated that the developed HPLC method is simple, sensitive and reliable. Moreover, the content of escins in seeds decreased by more than 30% in endosperm and by more than 40% in skin upon storage for two years.
CONCLUSIONS:
This assay can be readily utilized as a quality control method for horse chestnut and other related medicinal plants.

Product Name	Isoescin IB
Price:	$268 / 10mg
CAS No.:	219944-46-4
Catalog No.:	CFN90933
Molecular Formula:	C₅₅H₈₆O₂₄
Molecular Weight:	1131.3 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Aesculus hippocastanum L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	0.8839 mL	4.4197 mL	8.8394 mL	17.6788 mL	22.0985 mL
5 mM	0.1768 mL	0.8839 mL	1.7679 mL	3.5358 mL	4.4197 mL
10 mM	0.0884 mL	0.442 mL	0.8839 mL	1.7679 mL	2.2098 mL
50 mM	0.0177 mL	0.0884 mL	0.1768 mL	0.3536 mL	0.442 mL
100 mM	0.0088 mL	0.0442 mL	0.0884 mL	0.1768 mL	0.221 mL

CFN90934	Escin IB	26339-90-2	1131.3	C₅₅H₈₆O₂₄
CFN70258	Deacylgymnemic acid	121686-42-8	682.9	C₃₆H₅₈O₁₂
CFN90538	Gymnemic acid I	122168-40-5	806.97	C₄₃H₆₆O₁₄
CFN93368	Escin IA	123748-68-5	1131.3	C₅₅H₈₆O₂₄
CFN90932	Isoescin IA	219944-39-5	1131.3	C₅₅H₈₆O₂₄
CFN90933	Isoescin IB	219944-46-4	1131.3	C₅₅H₈₆O₂₄
CFN94818	Aescin IIA	158732-55-9	1101.23	C₅₄H₈₄O₂₃
CFN91688	Theasaponin E2	220114-30-7	1231.4	C₅₉H₉₀O₂₇
CFN91689	Theasaponin E1	220114-28-3	1231.4	C₅₉H₉₀O₂₇
CFN99509	Sodium Aescinate	20977-05-3	1124.2	C₅₄H₈₄NaO₂₃