Isolappaol C | CAS:929905-15-7 | Manufacturer ChemFaces

Isolappaol C

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $239.8 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Reference standards.

In vitro:

Chemical & Pharmaceutical Bulletin, 2007, 55(1):150-152.

Lignans from Arctium lappa and their inhibition of LPS-induced nitric oxide production.[Reference: WebLink]

METHODS AND RESULTS:
A new butyrolactone sesquilignan, Isolappaol C (1), together with four known lignans, lappaol C (2), lappaol D (3), lappaol F (4), and diarctigenin (5), were isolated from the methanolic extract of the seeds from the Arctium lappa plant. The structure of Isolappaol C (1) was determined by spectral analysis including 1D- and 2D-NMR. All the isolates were evaluated for their inhibitory effects on the LPS-induced nitric oxide production using murine macrophage RAW264.7 cells.
CONCLUSIONS:
Lappaol F (4) and diarctigenin (5) strongly inhibited NO production in the LPS-stimulated RAW264.7 cells with IC(50) values of 9.5 and 9.6 microM, respectively.

Isolappaol C Description

Source:	The roots of Gymnadenia conopsea
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Isolappaol C
Price:	$333 / 10mg
CAS No.:	929905-15-7
Catalog No.:	CFN95225
Molecular Formula:	C₃₀H₃₄O₁₀
Molecular Weight:	554.6 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The roots of Gymnadenia conopsea
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Lignans Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.8031 mL	9.0155 mL	18.031 mL	36.062 mL	45.0775 mL
5 mM	0.3606 mL	1.8031 mL	3.6062 mL	7.2124 mL	9.0155 mL
10 mM	0.1803 mL	0.9016 mL	1.8031 mL	3.6062 mL	4.5078 mL
50 mM	0.0361 mL	0.1803 mL	0.3606 mL	0.7212 mL	0.9016 mL
100 mM	0.018 mL	0.0902 mL	0.1803 mL	0.3606 mL	0.4508 mL

CFN95225	Isolappaol C	929905-15-7	554.6	C₃₀H₃₄O₁₀
CFN95069	Lappaol F	69394-17-8	714.8	C₄₀H₄₂O₁₂
CFN96715	(+)-Matairesinol	148409-36-3	358.39	C₂₀H₂₂O₆
CFN96234	Isosalicifolin	156974-99-1	356.4	C₂₀H₂₀O₆
CFN98454	Nortrachelogenin	34444-37-6	374.4	C₂₀H₂₂O₇
CFN96714	(+)-Nortrachelogenin	61521-74-2	374.38	C₂₀H₂₂O₇
CFN89300	(7R)-Methoxy-8-epi-matairesinol	198827-23-5	388.41	C₂₁H₂₄O₇
CFN90598	Trachelogenin	34209-69-3	388.15	C₂₁H₂₄O₇
CFN93080	Nortracheloside	33464-78-7	536.53	C₂₆H₃₂O₁₂
CFN90597	Tracheloside	33464-71-0	550.2	C₂₇H₃₄O₁₂