Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    L-Cystine
    L-Cystine
    Information
    CAS No. 56-89-3 Price $30 / 20mg
    Catalog No.CFN70150Purity>=98%
    Molecular Weight240.3Type of CompoundAlkaloids
    FormulaC6H12N2O4S2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $8.9 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Deutsches Krebsforschungszentrum (Germany)
  • Universidade Federal de Goias (... (Brazil)
  • Utrecht University (Netherlands)
  • Nanjing University of Chinese M... (China)
  • Medical University of Gdansk (Poland)
  • Technical University of Denmark (Denmark)
  • University of the Basque Country (Spain)
  • The Institute of Cancer Research (United Kingdom)
  • Leibniz Institute of Plant Bioc... (Germany)
  • Rio de Janeiro State University (Brazil)
  • University of Melbourne (Australia)
  • More...
  • Package
    Featured Products
    Alisol A 23-acetate

    Catalog No: CFN92544
    CAS No: 19865-75-9
    Price: $418/5mg
    Kumatakenin

    Catalog No: CFN98423
    CAS No: 3301-49-3
    Price: $238/10mg
    Ginsenoside Rg6

    Catalog No: CFN90565
    CAS No: 147419-93-0
    Price: $318/5mg
    Dihydromorin

    Catalog No: CFN99854
    CAS No: 18422-83-8
    Price: $403/5mg
    Ginsenoside Rk3

    Catalog No: CFN92593
    CAS No: 364779-15-7
    Price: $180/10mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $318/5mg
    Afzelin

    Catalog No: CFN98757
    CAS No: 482-39-3
    Price: $288/20mg

    L-Cystine

    L-Cystine
    Product Name L-Cystine
    CAS No.: 56-89-3
    Catalog No.: CFN70150
    Molecular Formula: C6H12N2O4S2
    Molecular Weight: 240.3 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Targets: GSH-Px | SOD | H1N1 | TNF-伪
    Source: The culture product of Escherichia coli.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $30 / 20mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Journal of Life Science2018, 917-922
  • BMC Plant Biol.2022, 22(1):128.
  • Revista Brasileira de Farmacognosia2021, 31:794-804.
  • Molecules.2019, 24(23):E4303
  • Molecules.2021, 26(4):1084.
  • Neurotox Res.2020, 38(1):163-174.
  • Molecules.2019, 24(21):E3834
  • Int J Mol Med.2019, 43(6):2516-2522
  • Food Funct.2022, doi: 10.1039
  • Environ Toxicol.2020, doi: 10.1002
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • TNF-α Inhibitor Library
  • SOD Inhibitor Library
  • Biological Activity
    Description: L-Cystine can improve hyperlipidemia by restoring LPL and HSL activities.L-Cystine protects against the toxicity of PQ by maintaining reduced glutathione levels in the cells. Co-administration of l-cystine and l-theanine before vaccination may enhance the immune response to influenza vaccine in elderly subjects with low serum total protein or hemoglobin.
    Targets: GSH-Px | SOD | H1N1 | TNF-α
    In vitro:
    Cytotechnology, 2010, 62(3):225-233.
    Effects of sulfur amino acids, L: -methionine, L: -cystine and L: -cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes.[Reference: WebLink]
    Rats subcutaneously implanted with AH109A hepatoma cells show hyperlipidemia with high concentrations of serum triglyceride and nonesterified fatty acid, suppression of lipoprotein lipase (LPL), and elevation of hormone-sensitive lipase (HSL) activities during the growth of the hepatoma. Supplementation of the diet with sulfur amino acids such as L -methionine (Met) and L-Cystine (Cys) improved hyperlipidemia by restoring LPL and HSL activities.
    METHODS AND RESULTS:
    In the present study, we have attempted to examine the effects of sulfur amino acids on the activity and mRNA level of LPL and the activity of HSL using 3T3-L1 cells, which are known to differentiate to adipocytes. The adipocytes were incubated with various concentrations of Met, Cys or L -cysteine (CysH) in the absence or presence of tumor necrosis factor-alpha (TNF-alpha). LPL activity was suppressed by TNF-alpha. In the absence of TNF-alpha, Met, Cys and CysH did not change the LPL activity. In the presence of TNF-alpha, Met and Cys significantly increased the LPL activity, and Met also enhanced the LPL mRNA level. HSL activity was also suppressed by TNF-alpha. In the absence of TNF-alpha, Met enhanced the HSL activity. In the presence of TNF-alpha, Met, Cys and CysH suppressed the HSL activity. Sulfur amino acids such as Met, Cys and CysH affected the LPL activity, mRNA level, and HSL activity in 3T3-L1 adipocytes.
    CONCLUSIONS:
    Some of these effects of sulfur amino acids were different between LPL and HSL, between the absence and the presence of TNF-alpha, and between 3T3-L1 adipocytes and the adipose tissue from rats.
    In vivo:
    Geriatrics & Gerontology International, 2010, 8(4):243-250.
    Co-administration of L-cystine and L-theanine enhances efficacy of influenza vaccination in elderly persons: Nutritional status-dependent immunogenicity.[Reference: WebLink]
    The immune response to influenza vaccine is attenuated in elderly persons, though they are at greatest risk for morbidity and mortality by influenza virus infection.
    METHODS AND RESULTS:
    Experimental studies demonstrate that co-administration of L-Cystine and l-theanine enhanced antigen-specific production of immunoglobulin in aged mice infected with influenza virus. We thus investigated the effect of L-Cystine and l-theanine on antibody induction by influenza vaccines in elderly persons. Residents in a nursing home were randomly allocated to L-Cystine and l-theanine (n = 32) or placebo (n = 33). The test substances were administered p.o. for 14 days before immunization. Serum influenza virus antibody titers were measured before and 4 weeks after vaccination. Vaccination significantly elevated hemagglutination inhibition (HI) titers for all the three strains of influenza viruses (A/New Caledonia [H1N1], A/New York [H3N2] and B/Shanghai) in both groups. HI titers after vaccination were not significantly different between the two groups for either strain. Also, the seroconversion rate was not significantly different between the two groups in the aggregate. A stratified analysis showed that the rate of seroconversion was significantly greater in the L-Cystine and l-theanine group compared with the placebo group for influenza virus A (H1N1) among subjects with low serum total protein (63% vs 10%, P < 0.05) or low hemoglobin (71% vs 9%, P < 0.05).
    CONCLUSIONS:
    Co-administration of L-Cystine and l-theanine before vaccination may enhance the immune response to influenza vaccine in elderly subjects with low serum total protein or hemoglobin.
    Toxicology Letters, 1992, 60(1):75-82.
    Effect of l-cystine on toxicity of paraquat in mice.[Reference: WebLink]

    METHODS AND RESULTS:
    The protective effect of L-Cystine on the toxicity of paraquat (PQ) in mice was studied. Lipid peroxidation in the lung significantly increased after oral administration of PQ (200 mgkg) and the increase in lipid peroxidation was prevented by L-Cystine treatment (300 mgkg). PQ administration produced an increase in Superoxide dismutase (SOD) activity and a decrease in glutathione peroxidase (GSH-Px) activity in the lung at 24 h after PQ. L-Cystine treatment significantly prevented the changes in SOD and GSH-Px activity in the lung after PQ. L-Cystine treatment prevented the decrease in non-protein sulfhydryl (NP-SH) content in the lung after PQ administration. The tissue distribution and excretion of PQ after PQ administration were not changed by L-Cystine treatment. Plasma aspartate aminotransferase activity did not change after PQ administration.
    CONCLUSIONS:
    These results suggest that L-Cystine protects against the toxicity of PQ by maintaining reduced glutathione levels in the cells.
    L-Cystine Description
    Source: The culture product of Escherichia coli.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    3,7,25-Trihydroxycucurbita-5,23-di...

    Catalog No: CFN95150
    CAS No: 85372-65-2
    Price: $318/5mg
    Methyl ganoderenate B

    Catalog No: CFN95534
    CAS No: N/A
    Price: $413/5mg
    ent-16beta,17-dihydroxy-9(11)-kaur...

    Catalog No: CFN95172
    CAS No: 55483-24-4
    Price: $318/10mg
    Rosmarinyl glucoside

    Catalog No: CFN95297
    CAS No: 910028-78-3
    Price: $413/5mg
    Polygalin J

    Catalog No: CFN95175
    CAS No: N/A
    Price: $318/5mg
    Elgonica dimer A

    Catalog No: CFN95445
    CAS No: 132210-48-1
    Price: $368/5mg
    Cyclocurcumin

    Catalog No: CFN95103
    CAS No: 153127-42-5
    Price: $368/10mg
    Cuscutamine

    Catalog No: CFN95323
    CAS No: 122170-93-8
    Price: $318/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1615 mL 20.8073 mL 41.6146 mL 83.2293 mL 104.0366 mL
    5 mM 0.8323 mL 4.1615 mL 8.3229 mL 16.6459 mL 20.8073 mL
    10 mM 0.4161 mL 2.0807 mL 4.1615 mL 8.3229 mL 10.4037 mL
    50 mM 0.0832 mL 0.4161 mL 0.8323 mL 1.6646 mL 2.0807 mL
    100 mM 0.0416 mL 0.2081 mL 0.4161 mL 0.8323 mL 1.0404 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Alisol A 23-acetate

    Catalog No: CFN92544
    CAS No: 19865-75-9
    Price: $418/5mg
    Kumatakenin

    Catalog No: CFN98423
    CAS No: 3301-49-3
    Price: $238/10mg
    Ginsenoside Rg6

    Catalog No: CFN90565
    CAS No: 147419-93-0
    Price: $318/5mg
    Dihydromorin

    Catalog No: CFN99854
    CAS No: 18422-83-8
    Price: $403/5mg
    Ginsenoside Rk3

    Catalog No: CFN92593
    CAS No: 364779-15-7
    Price: $180/10mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $318/5mg
    Afzelin

    Catalog No: CFN98757
    CAS No: 482-39-3
    Price: $288/20mg