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L(-)-Tryptophan
L(-)-Tryptophan
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name L(-)-Tryptophan
Price: $30 / 20mg
CAS No.: 73-22-3
Catalog No.: CFN70193
Molecular Formula: C11H12N2O2
Molecular Weight: 204.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $8.9 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vivo:
Neuropharmacology, 1976, 15(6):339-344.
Dose-response relationships between systemically administered l-tryptophan or l-5-hydroxytryptophan and raphe unit activity in the rat.[Reference: WebLink]

METHODS AND RESULTS:
In contrast to previous reports that l-5-hydroxytryptophan (l-5-HTP) is without effect on raphe unit activity, systemic administration of l-tryptophan(L(-)-Tryptophan) or l-5-HTP produced similar dose-dependent decreases in raphe unit activity, ranging from 0–15% at 10 mg/kg to 60–90% at 100 mg/kg doses. The dose-response curve forms a plateau for doses above 100 mg/kg of l-5-HTP or l-tryptophan. Neurochemical studies revealed that administration of varying doses of l-tryptophan or l-5-HTP (10–100 mg/kg, i.p.) under conditions simulating those of the unit recording procedure, produced dosedependent increases in forebrain serotonin of up to 42% and 353% for a 100 mg/kg dose of l-tryptophan or l-5-HTP, respectively.
CONCLUSIONS:
These data suggest that exogeneously administered l-5-HTP serves as an effective serotonin precursor in central serotonergic neurones. Furthermore, increases in forebrain serotonin levels within the range of normal diurnal variations dramatically depress raphe unit activity, indicating that diurnal changes in brain serotonin metabolism may significantly affect the activity of serotonin-containing neurones.
L(-)-Tryptophan Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.8972 mL 24.4858 mL 48.9716 mL 97.9432 mL 122.429 mL
5 mM 0.9794 mL 4.8972 mL 9.7943 mL 19.5886 mL 24.4858 mL
10 mM 0.4897 mL 2.4486 mL 4.8972 mL 9.7943 mL 12.2429 mL
50 mM 0.0979 mL 0.4897 mL 0.9794 mL 1.9589 mL 2.4486 mL
100 mM 0.049 mL 0.2449 mL 0.4897 mL 0.9794 mL 1.2243 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $168/20mg
1-Acetyl-beta-carboline

Catalog No: CFN92122
CAS No: 50892-83-6
Price: $ / mg
Ascorbic acid

Catalog No: CFN90048
CAS No: 50-81-7
Price: $30/20mg
Phyllanthin

Catalog No: CFN99050
CAS No: 10351-88-9
Price: $288/10mg
4-Methoxyglucobrassicin

Catalog No: CFN00505
CAS No: 83327-21-3
Price: $ / mg
Rhapontigenin

Catalog No: CFN92607
CAS No: 500-65-2
Price: $118/20mg
Pinostrobin chalcone

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CAS No: 18956-15-5
Price: $368/20mg
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Oxyresveratrol

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Angelicide

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Price: $ / mg
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