ChemFaces is a professional high-purity natural products manufacturer.
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $413 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Pharmacogn Mag.2015, 11(43):562-6Phytomedicine.2015, 22(4):498-503HortTechnology2016, 26(6):816-819Sci Rep.2016, 6:25094Planta Med.2016, 82(13):1208-16Hum Exp Toxicol.2017, 36(11):1169-1176Universidade Estadual Paulista...2017...Sci Rep.2017, 7(1):3249
J Pharm Biomed Anal.2018, 151:32-41Molecules.2018, 23(7):E1817Biochemical Systematics and Ecolo...2018...Molecules.2019, 24(19):E3417Molecules.2019, 24(24),4583Molecules.2019, 24(9):E1719Food and Fermentation Industries...2019...Phytomedicine.2019, 55:229-237
Ann Transl Med.2019, 7(23):731Pharmacol Rep.2019, 71(2):289-298Int Immunopharmacol.2019, 71:22-31Sci Rep.2019, 9(1):6429Horticulturae2020, 6(4),76.Korean Herb. Med. Inf....2020...Food Chem.2021, 337:128023.
Our products had been exported to the following research institutions and universities, And still growing.
Srinakharinwirot University (Thailand)Universidade Federal de Santa C... (Brazil)Wageningen University (Netherlands)University of Auckland (New Zealand)
Universidad Industrial de Santa... (Colombia)Instytut Nawozów Sztucznych w ... (Poland)Funda??o Universitária de Dese... (Brazil)Kyung Hee University (Korea)
Florida A&M University (USA)Institute of Chinese Materia Me... (China)University of Mysore (India)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Molecules.2019, 24(4):E744The Journal of Animal & Plant Sciences.2020, 30(6):1366-1373FASEB J.2019, 33(8):9685-9694J Agric Food Chem.2017, 65(13):2670-2676Int J Mol Med.2015, 35(5):1237-45Int J Mol Sci.2020, 21(19),7070.Oncology Letters2018, 4690-4696Int J Mol Sci.2015, 16(8):18396-411Food Chem.2019, 290:286-294Asian Pac J Cancer Prev. 2020, 21(4):935-941.
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Phenols Compound Library
Diosniposide B Description
||The herbs of Bletilla striata
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Ethnopharmacol . 2014 Sep 11;155(2):1164-70 |
|Phenolic derivatives from the rhizomes of Dioscorea nipponica and their anti-neuroinflammatory and neuroprotective activities[Pubmed: 24973689]|
|Ethnopharmacological relevance: Dioscorea nipponica (Dioscoreaceae) have been used as traditional medicines for diabetes, inflammatory and neurodegenerative diseases in Korea. The aim of the study was to isolate the bioactive components from the rhizomes of Dioscorea nipponica and to evaluate their anti-neuroinfalmmatory and neuroprotective activities.
Material and methods: The phytochemical investigation of 50% EtOH extract of Dioscorea nipponica using successive column chromatography over silica gel, Sephadex LH-20, and preparative high performance liquid chromatography (HPLC) resulted in the isolation and identification of 17 phenolic derivatives, including four new phenolic compounds (1-4). The structural elucidation of these compounds was based on spectroscopic methods, including 1D and 2D nuclear magnetic resonance (NMR) spectroscopy techniques, mass spectrometry, and optical rotation. All isolated compounds were evaluated for their effects on nerve growth factor (NGF) secretion in a C6 rat glioma cell line and nitric oxide (NO) production in lipopolysaccharide (LPS)-activated BV2 cells. The neurite outgrowth of compound 16 was further evaluated by using mouse neuroblastoma N2a cell lines.
Results: Three new stilbene derivatives, diosniponol C (1), D (2) and diosniposide A (3) and one new phenanthrene glycoside, Diosniposide B (4), together with 13 known compounds were isolated from the rhizomes of Dioscorea nipponica. Of the tested compounds (1-17), phenanthrene, 3,7-dihydroxy-2,4,6-trimethoxy-phenanthrene (16) was the most potent NGF inducer, with 162.35±16.18% stimulation, and strongly reduced NO levels with an IC50 value of 19.56 μM in BV2 microglial cells. Also, it significantly increased neurite outgrowth in N2a cells.
Conclusions: This study supports the ethnopharmacological use of Dioscorea nipponica rhizomes as traditional medicine.|