ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
Contact Us
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Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $175.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
ACS Omega2020, 5,33,20825-20830Naunyn Schmiedebergs Arch Pharmac...2017...Korean J. of Horticultural Sci. &...2017...Current Topics in Nutraceutical R...2021...BMC Complement Altern Med.2016, 16:213J Exp Bot.2016, 67(12):3777-88J of Ana. Chem.2019, 74(11):1113-1121The Journal of Supercritical Flui...2021...
J Agric Food Chem.2016, 64(35):6783-90J Pharmaceutical and Biomedical A...2022...Int J Oncol.2016, 49(4):1497-504HIV Med.2021, 22(8):690-704.Toxicol In Vitro.2018, 52:94-105Asian Journal of Chemistry...2018...Proc Natl Acad Sci USA....2016...Chem Pharm Bull (Tokyo)....2019...
Anticancer Res.2014, 34(7):3505-9Appl. Sci.2021, 11(24),12080Chemistry of Plant Materials....2019...The Japan Society for Analy. Chem...2017...Toxicol Res.2019, 35(4):371-387Food Chem. 2020, 320:126530J Vet Sci.2020, 21(3):e39.
More...
Our products had been exported to the following research institutions and universities, And still growing.
Shanghai University of TCM (China)The Ohio State University (USA)Wageningen University (Netherlands)National Cancer Center Research... (Japan)
University of Brasilia (Brazil)The Institute of Cancer Research (United Kingdom)Universiti Putra Malaysia(UPM) (Malaysia)University of Padjajaran (Indonesia)
St. Jude Children Research Hosp... (USA)University of Toronto (Canada)Pennsylvania State University (USA)
More...
Magnolignan A
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manager@chemfaces.com
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service@chemfaces.com
Tel:
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Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Scientific World Journal.2014, 2014:654193Int J Vitam Nutr Res.2022, doi: 10.1024.The Malaysian journal of pathology2019, 41(3):243-251Chem Biol Interact.2016, 260:168-175Journal of Functional Foods2021, 84:104581BMC Pharmacol Toxicol.2018, 19(1):5PLoS One.2021, 16(9):e0257243.J Cell Mol Med.2018, 22(9):4236-4242New Journal of Chemistry2019, 43:12538-12547 Pharmaceuticals (Basel). 2021, 14(10):986.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Lignans Compound Library |
| Description: |
Magnolignan A-2-O-beta-D-glucopyranoside has medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, and 46.4 microM, respectively. |
| In vitro: |
| Magn Reson Chem. 2008 May;46(5):497-500. | | 1H and 13C NMR assignments for two lignans from the heartwood of Streblus asper.[Pubmed: 18297743 ] |
METHODS AND RESULTS:
In our ongoing investigation of the bioactive constituents from plants, two new lignans, Magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol were isolated from heartwood of Streblus asper, along with three known lignans, Magnolignan A, magnolol, and magnaldehyde D. 1D and 2D NMR experiments, including COSY, HMQC, and HMBC, and other spectroscopic methods, including UV, IR, and MS were used for the determination of the structures and NMR assignments.
CONCLUSIONS:
Primary bioassays showed that Magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol have medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, 46.4 microM and 10.1 microM, 21.7 microM, respectively. |
|
Magnolignan A Description
| Source: |
The barks of Magnolia officinalis |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.3289 mL |
16.6445 mL |
33.2889 mL |
66.5779 mL |
83.2224 mL |
| 5 mM |
0.6658 mL |
3.3289 mL |
6.6578 mL |
13.3156 mL |
16.6445 mL |
| 10 mM |
0.3329 mL |
1.6644 mL |
3.3289 mL |
6.6578 mL |
8.3222 mL |
| 50 mM |
0.0666 mL |
0.3329 mL |
0.6658 mL |
1.3316 mL |
1.6644 mL |
| 100 mM |
0.0333 mL |
0.1664 mL |
0.3329 mL |
0.6658 mL |
0.8322 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Natural Medicines, 1999 , 53 :1-4. | | The simple method of distinction between Japanese and Chinese magnolia bark by ion-pair high-performance liquid chromatography using photodiode array detector[Reference: WebLink] | | To establish a simple method for making distinction between Japanese and Chinese magnolia barks, the components in both magnolia barks were analysed by ion-pair high performance liquid chromatography using a photodiode array detector. Methyleugenol and Magnolignan A were detected only in Chinese magnolia barks. The presence or absence, of these components distinguishes Japanese magnolia barks from Chinese magnolia barks. The amounts these components in Chinese magnolia barks were determined. |
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