ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Methyl ganoderate A
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $475.0 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules.2021, 26(9):2802. Cardiovasc Toxicol.2019, 19(4):297-305BMC Complement Med Ther. ...2020...Sci Rep.2018, 8(1)Molecules.2019, 24(19):E3417Front Pharmacol.2021, 12:762829. Korean J. Medicinal Crop Sci...2021...Int J Mol Sci.2021, 22(2):770.
Sci Rep.2021, 11(1):14180. JPC-Journal of Planar Chromatogra...2017...Process Biochemistry2019, 87:213-220J Sep Sci.2022, 45(18):3556-3566.Bull. Natl. Mus. Nat. Sci....2021...bioRxiv2021, 462065.Anal Chim Acta.2018, 1039:162-171Molecules2022, 27(12):3903.
Oncol Rep.2019, 41(4):2453-2463Current Traditional Medicine, ...2021...Nat Commun.2019, 10(1):5169Allergol Immunopathol (Madr)....2022...J Chromatogr B Analyt Technol Bio...2019...Chem. of Vegetable Raw Materials...2020...Agriculture2022, 12(2),227.
Our products had been exported to the following research institutions and universities, And still growing.
Chang Gung University (Taiwan)Mendel University in Brno (Czech Republic)Molecular Biology Institute of ... (Spain)Technical University of Denmark (Denmark)
Center for protein Engineering ... (Belgium)Univerzita Karlova v Praze (Czech Republic)Ateneo de Manila University (Philippines)Leibniz-Institut für Pflanzenb... (Germany)
Cornell University (USA)Universidade Federal de Goias (... (Brazil)Kitasato University (Japan)
Methyl ganoderate A
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Int Immunopharmacol.2019, 71:22-31J Herbmed Pharmacol.2018, 7(4):280-286Evid Based Complement Alternat Med.2018, 2018:8565132Molecules.2018, 23(11):E2837Int J Mol Med.2019, 43(6):2516-2522Nat Prod Commun.2014, 9(5):679-82The Journal of Agromedicine and Medical Sciences2018, 4(1)Biochem Pharmacol.2020, 178:114083Plant Sci.2021, 313:111069.Foods.2022, 11(12):1708.
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Methyl ganoderate A is a Farnesyl protein transferase (FPT) inhibitor with an IC50 value of 38 microM,which has potential anticancer effects.Methyl ganoderate A has inhibitory effect on fatty acid amide hydrolase (FAAH).|
Methyl ganoderate A Description
||The fruit body of Ganoderma lucidum
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Planta Med . 1998 May;64(4):303-308. |
|Natural inhibitors for protein prenyltransferase[Pubmed: 9619109]|
|Farnesyl protein transferase (FPT) catalyzes the posttranslational farnesylation of the cysteine residue located in the carboxyl-terminal tetrapeptide of the Ras oncoprotein. Prenylation of this residue is essential for membrane association and cell transforming activities of Ras. Inhibitors of FPT have been demonstrated to inhibit Ras-dependent cell transformation and thus represent a potential therapeutic strategy for the treatment of human cancers (1). In the present study, the inhibitory principles for protein prenyltransferases were isolated and identified from Ganoderma lucidum and garlic. The inhibitors from Ganoderma lucidum were identified as ganoderic acid A and ganoderic acid C by comparison with the reported spectral data. Ganoderic acid A has an IC50 value of 100 microM against FPT and its methyl ester (Methyl ganoderate A) has an IC50 value of 38 microM for the same enzyme. These inhibitors appear to be competitive with farnesyl pyrophosphate (FPP), and Ki values of ganoderic acid A and Methyl ganoderate A are 54 microM and 20 microM, respectively. The inhibitors from garlic were identified as diallyl thiosulfinate (allicin), methyl allyl thiosulfinate, and allyl methyl thiosulfinate. These inhibitors are more effective against geranylgeranyl protein transferase (GGPT) than FPT and IC50 values of allicin, methyl allyl thiosulfinate, and allyl methyl thiosulfinate for GGPT were 43 microM, 57 microM, and 53 microM, respectively. Methyl allyl thiosulfinate appears to be competitive with geranylgeranyl pyrophosphate (GGPP) and its Ki was determined to be 15 microM. The molecular structures of triterpenes and thiosulfinates are expected to be useful in designing lead compounds for new potent antitumour agents.|
Tags: buy Methyl ganoderate A | Methyl ganoderate A supplier | purchase Methyl ganoderate A | Methyl ganoderate A cost | Methyl ganoderate A manufacturer | order Methyl ganoderate A | Methyl ganoderate A distributor