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    Natural Products
    Vicinin 2
    Vicinin 2
    Information
    CAS No. 90456-53-4 Price $368 / 5mg
    Catalog No.CFN95249Purity>95%
    Molecular Weight626.5Type of CompoundFlavonoids
    FormulaC27H30O17Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $478.4 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Vicinin 2

    Vicinin 2
    Product Name Vicinin 2
    CAS No.: 90456-53-4
    Catalog No.: CFN95249
    Molecular Formula: C27H30O17
    Molecular Weight: 626.5 g/mol
    Purity: >95%
    Type of Compound: Flavonoids
    Physical Desc.: Powder
    Source: The herbs of Vicia sativa L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $368 / 5mg
    Inquire / Order: manager@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Flavonoids Compound Library
  • Biological Activity
    Description: Reference standards.
    In vitro:
    European scientific journal, 2013,9(18):217-228.
    BIOACTIVITY OF ANTIDESMA BUNIUS LEAVES (EUPHORBIACEAE) AND THEIR MAJOR PHENOLIC CONSTITUENTS.[Reference: WebLink]

    METHODS AND RESULTS:
    Chromatographic fractionation of the methanol extract of Antidesma bunius leaves afforded six polyphenols, namely, corilagin (1), gallic (2), ferrulic (3) and ellagic (4) acids in addition to the flavone vicinin II [(Vicinin 2), 5] and the dimmer amentoflavone (6). Their structures were elucidated by NMR and HRESI analysis. This is the first reported occurrence of the biflavone (amentoflavone) and vicinin in this species. The total phenolic content was estimated at 90 mg/ml of gallic acid equivalent (GAE) per 100 g plant extract using the Folin-Ciocalteu method. Antioxidant biochemical assay of the plant methanol extract was carried out using culture medium of hepatocyte cell lines. An increase in glutathione reductase enzyme and a reduction of the nitric oxide level in the cell culture revealed that A. bunius leaf extract possesses significant antioxidant activity in comparing with quercetine as a reference. The hepatotoxicity and hepatoprotective activities of A.bunius leaf extract and the pure isolated compounds: 1 , 2 and 5 were evaluated by adopting the MTT colorimetric assay.
    CONCLUSIONS:
    Compounds 1 and 2 revealed a margin of safety on the monolayer hepatocyte with an IC50 > 1000 μg/ml while for 5, IC50 was at 125 μg/ml. The hepatoprotective activities for A.bunius leaf extract, 1 and 2 in comparison to Silymarin (50 μg/ml) were at 6.5, <12.5 and 12.5 μg/ml respectively while 5 did not show hepatoprotective activity at the tested concentrations.
    Vicinin 2 Description
    Source: The herbs of Vicia sativa L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5962 mL 7.9808 mL 15.9617 mL 31.9234 mL 39.9042 mL
    5 mM 0.3192 mL 1.5962 mL 3.1923 mL 6.3847 mL 7.9808 mL
    10 mM 0.1596 mL 0.7981 mL 1.5962 mL 3.1923 mL 3.9904 mL
    50 mM 0.0319 mL 0.1596 mL 0.3192 mL 0.6385 mL 0.7981 mL
    100 mM 0.016 mL 0.0798 mL 0.1596 mL 0.3192 mL 0.399 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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