ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Vicinin 2
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
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Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $478.4 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Phytomedicine.2017, 24:77-86Journal of Apiculture...2019...Acta Pharm Sin B.2015, 5(4):323-9.Appl. Sci. 2021, 11(8),3437.Journal of Food Composition and A...2021...Sci Adv.2018, 4(10)US20170000760 A12016, 42740Nutraceutical Research . ...2021...
Biomed Pharmacother.2019, 116:108987Mol Pharm.2018, 15(8):3285-3296Exp Ther Med.2019, 18(6):4388-4396Appl Biol Chem2019, 62:46Journal of Ginseng Research...2021...Nutrients2022, 14(3),695.Phytomedicine.2016, 23(4):331-9Evid Based Complement Alternat Me...2020...
Molecules.2020, 25(11):2599. J Pharmacol Sci.2021, 147(2):184-191.Antioxidants (Basel).2021, 10(9):1487.Mediators Inflamm. 2016, 2016:6189590Pharmaceuticals (Basel). ...2021...Food Chem.2019, 276:768-775Int J Mol Sci.2021, 22(11):5503.
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Our products had been exported to the following research institutions and universities, And still growing.
Universidade de Franca (Brazil)Sant Gadge Baba Amravati Univer... (India)University of South Australia (Australia)University of Limpopo (South Africa)
Universite de Lille1 (France)Osmania University (India)University of Toulouse (France)Universidad Miguel Hernández (Spain)
National Research Council of Ca... (Canada)Aveiro University (Portugal)Kyushu University (Japan)
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Vicinin 2
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Antiviral Res.2013, 98(3):386-93ACS Chem Biol.2019, 14(5):873-881Phytother Res.2019, 33(5):1490-1500Biochem Pharmacol.2017, 130:10-20Molecules. 2013, 18(7):7376-88JAOCS2021, 98(7):779-794.South African Journal of Botany2021, 142:114-123.Cell Physiol Biochem.2019, 52(6):1255-1266J Sci Food Agric.2018, 98(3):1153-1161Nutrients2020, 12(3):811.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Flavonoids Compound Library |
| Description: |
Reference standards. |
| In vitro: |
| European scientific journal, 2013,9(18):217-228. | | BIOACTIVITY OF ANTIDESMA BUNIUS LEAVES (EUPHORBIACEAE) AND THEIR MAJOR PHENOLIC CONSTITUENTS.[Reference: WebLink] |
METHODS AND RESULTS:
Chromatographic fractionation of the methanol extract of Antidesma bunius leaves afforded six polyphenols, namely, corilagin (1), gallic (2), ferrulic (3) and ellagic (4) acids in addition to the flavone vicinin II [(Vicinin 2), 5] and the dimmer amentoflavone (6). Their structures were elucidated by NMR and HRESI analysis. This is the first reported occurrence of the biflavone (amentoflavone) and vicinin in this species. The total phenolic content was estimated at 90 mg/ml of gallic acid equivalent (GAE) per 100 g plant extract using the Folin-Ciocalteu method. Antioxidant biochemical assay of the plant methanol extract was carried out using culture medium of hepatocyte cell lines. An increase in glutathione reductase enzyme and a reduction of the nitric oxide level in the cell culture revealed that A. bunius leaf extract possesses significant antioxidant activity in comparing with quercetine as a reference. The hepatotoxicity and hepatoprotective activities of A.bunius leaf extract and the pure isolated compounds: 1 , 2 and 5 were evaluated by adopting the MTT colorimetric assay.
CONCLUSIONS:
Compounds 1 and 2 revealed a margin of safety on the monolayer hepatocyte with an IC50 > 1000 μg/ml while for 5, IC50 was at 125 μg/ml. The hepatoprotective activities for A.bunius leaf extract, 1 and 2 in comparison to Silymarin (50 μg/ml) were at 6.5, <12.5 and 12.5 μg/ml respectively while 5 did not show hepatoprotective activity at the tested concentrations. |
|
Vicinin 2 Description
| Source: |
The herbs of Vicia sativa L. |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.5962 mL |
7.9808 mL |
15.9617 mL |
31.9234 mL |
39.9042 mL |
| 5 mM |
0.3192 mL |
1.5962 mL |
3.1923 mL |
6.3847 mL |
7.9808 mL |
| 10 mM |
0.1596 mL |
0.7981 mL |
1.5962 mL |
3.1923 mL |
3.9904 mL |
| 50 mM |
0.0319 mL |
0.1596 mL |
0.3192 mL |
0.6385 mL |
0.7981 mL |
| 100 mM |
0.016 mL |
0.0798 mL |
0.1596 mL |
0.3192 mL |
0.399 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
