Vicinin 2 | CAS:90456-53-4 | Manufacturer ChemFaces

Vicinin 2

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $478.4 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Reference standards.

In vitro:

European scientific journal, 2013,9(18):217-228.

BIOACTIVITY OF ANTIDESMA BUNIUS LEAVES (EUPHORBIACEAE) AND THEIR MAJOR PHENOLIC CONSTITUENTS.[Reference: WebLink]

METHODS AND RESULTS:
Chromatographic fractionation of the methanol extract of Antidesma bunius leaves afforded six polyphenols, namely, corilagin (1), gallic (2), ferrulic (3) and ellagic (4) acids in addition to the flavone vicinin II [(Vicinin 2), 5] and the dimmer amentoflavone (6). Their structures were elucidated by NMR and HRESI analysis. This is the first reported occurrence of the biflavone (amentoflavone) and vicinin in this species. The total phenolic content was estimated at 90 mg/ml of gallic acid equivalent (GAE) per 100 g plant extract using the Folin-Ciocalteu method. Antioxidant biochemical assay of the plant methanol extract was carried out using culture medium of hepatocyte cell lines. An increase in glutathione reductase enzyme and a reduction of the nitric oxide level in the cell culture revealed that A. bunius leaf extract possesses significant antioxidant activity in comparing with quercetine as a reference. The hepatotoxicity and hepatoprotective activities of A.bunius leaf extract and the pure isolated compounds: 1 , 2 and 5 were evaluated by adopting the MTT colorimetric assay.
CONCLUSIONS:
Compounds 1 and 2 revealed a margin of safety on the monolayer hepatocyte with an IC50 > 1000 μg/ml while for 5, IC50 was at 125 μg/ml. The hepatoprotective activities for A.bunius leaf extract, 1 and 2 in comparison to Silymarin (50 μg/ml) were at 6.5, <12.5 and 12.5 μg/ml respectively while 5 did not show hepatoprotective activity at the tested concentrations.

Vicinin 2 Description

Source:	The herbs of Vicia sativa L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Vicinin 2
Price:	$368 / 5mg
CAS No.:	90456-53-4
Catalog No.:	CFN95249
Molecular Formula:	C₂₇H₃₀O₁₇
Molecular Weight:	626.5 g/mol
Purity:	>95%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Vicia sativa L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.5962 mL	7.9808 mL	15.9617 mL	31.9234 mL	39.9042 mL
5 mM	0.3192 mL	1.5962 mL	3.1923 mL	6.3847 mL	7.9808 mL
10 mM	0.1596 mL	0.7981 mL	1.5962 mL	3.1923 mL	3.9904 mL
50 mM	0.0319 mL	0.1596 mL	0.3192 mL	0.6385 mL	0.7981 mL
100 mM	0.016 mL	0.0798 mL	0.1596 mL	0.3192 mL	0.399 mL

CFN70208	2,4,6-Trihydroxybenzoic acid	83-30-7	170.1	C₇H₆O₅
CFN97082	Viniferol D	625096-18-6	680.7	C₄₂H₃₂O₉
CFN97680	Deacetylnimbinene	78916-55-9	440.54	C₂₆H₃₂O₆
CFN91727	L-Hydroxyproline	51-35-4	131.13	C₅H₉NO₃