ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Vicinin 2
Citing Use of our Products
How to Order
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $478.4 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
China Pharmacy2015, 26(27)Acta Agriculturae Scandinavica...2015...J Nat Prod.2015, 78(6):1339-4Food Sci Biotechnol....2016...J Pharm Anal.2016, 6(6):363-373Oncotarget.2016, 8(51):88386-88400PLoS One.2017, 12(8):e0181191RSC Advances2017, 86
Chem Biol Interact.2018, 290:44-51Phytomedicine.2018, 38:12-23Anal Bioanal Chem....2018...Front Immunol.2018, 9:2091Molecules.2019, 24(10):E1926Molecules.2019, 24(7):E1290J Ethnopharmacol.2019, 244:112074The Korea Journal of Herbology...2019...
Planta Med.2019, 85(4):347-355Biochem Biophys Res Commun....2020...Cell Metab.2020, S1550-4131(20)30002-4Front Microbiol.2020, 11:583594.J Biotechnol.2020, 318:10-19.SCOPUS.2020, 836-847.Nature Ecology & Evolution...2020...
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Our products had been exported to the following research institutions and universities, And still growing.
Cancer Research Initatives Foun... (Malaysia)Heinrich-Heine-University Düss... (Germany)Universidad Miguel Hernández (Spain)University of Limpopo (South Africa)
University of Wollongong (Australia)University of Maryland (USA)University of Fribourg (Switzerland)University of Otago (New Zealand)
Kyushu University (Japan)Periyar University (India)Universiti Putra Malaysia(UPM) (Malaysia)
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Vicinin 2
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Cell Biochem.2018, 119(2):2231-2239Neurochem Int.2018, 121:114-124J Breast Cancer.2015, 18(2):112-118Front Pharmacol.2017, 8:673LWT2020, 130:109535Biol Pharm Bull.2020, 43(10):1534-1541.BMC Complement Altern Med.2019, 19(1):325J Korean Soc Food Sci Nutr2020, doi: 10.3746.Analytical sci. & Tech2016, 186-193Plant Cell Tiss Org2020, 1-16
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Flavonoids Compound Library |
| Description: |
Reference standards. |
| In vitro: |
| European scientific journal, 2013,9(18):217-228. | | BIOACTIVITY OF ANTIDESMA BUNIUS LEAVES (EUPHORBIACEAE) AND THEIR MAJOR PHENOLIC CONSTITUENTS.[Reference: WebLink] |
METHODS AND RESULTS:
Chromatographic fractionation of the methanol extract of Antidesma bunius leaves afforded six polyphenols, namely, corilagin (1), gallic (2), ferrulic (3) and ellagic (4) acids in addition to the flavone vicinin II [(Vicinin 2), 5] and the dimmer amentoflavone (6). Their structures were elucidated by NMR and HRESI analysis. This is the first reported occurrence of the biflavone (amentoflavone) and vicinin in this species. The total phenolic content was estimated at 90 mg/ml of gallic acid equivalent (GAE) per 100 g plant extract using the Folin-Ciocalteu method. Antioxidant biochemical assay of the plant methanol extract was carried out using culture medium of hepatocyte cell lines. An increase in glutathione reductase enzyme and a reduction of the nitric oxide level in the cell culture revealed that A. bunius leaf extract possesses significant antioxidant activity in comparing with quercetine as a reference. The hepatotoxicity and hepatoprotective activities of A.bunius leaf extract and the pure isolated compounds: 1 , 2 and 5 were evaluated by adopting the MTT colorimetric assay.
CONCLUSIONS:
Compounds 1 and 2 revealed a margin of safety on the monolayer hepatocyte with an IC50 > 1000 μg/ml while for 5, IC50 was at 125 μg/ml. The hepatoprotective activities for A.bunius leaf extract, 1 and 2 in comparison to Silymarin (50 μg/ml) were at 6.5, <12.5 and 12.5 μg/ml respectively while 5 did not show hepatoprotective activity at the tested concentrations. |
|
Vicinin 2 Description
| Source: |
The herbs of Vicia sativa L. |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.5962 mL |
7.9808 mL |
15.9617 mL |
31.9234 mL |
39.9042 mL |
| 5 mM |
0.3192 mL |
1.5962 mL |
3.1923 mL |
6.3847 mL |
7.9808 mL |
| 10 mM |
0.1596 mL |
0.7981 mL |
1.5962 mL |
3.1923 mL |
3.9904 mL |
| 50 mM |
0.0319 mL |
0.1596 mL |
0.3192 mL |
0.6385 mL |
0.7981 mL |
| 100 mM |
0.016 mL |
0.0798 mL |
0.1596 mL |
0.3192 mL |
0.399 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
