ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Int J Mol Sci.2019, 20(11):E2734Univerzita Karlova2021, 20.500.11956.Nat Prod Commun.2014, 9(5):679-82Int J Biol Macromol....2020...Food Research International...2016...J. of Med. Plant Research.2013, 90-151Saudi Pharm J.2019, 27(1):145-153Korean Journal of Pharmacognosy...2019...
J of Applied Pharmaceutical Scien...2020...BMC Plant Biol.2020, 20(1):214. Phytomedicine.2019, 65:153089Toxins (Basel).2021, 13(9):593. Appl. Sci.2021, 11(1),14.Pharmaceuticals (Basel). ...2021...Asian Pac J Cancer Prev....2021...Molecules 2022, 27(3),1047.
J Nat Med.2017, 71(4):745-756Food and Chemical Toxicology...2020...Biomed Pharmacother.2019, 111:262-269Int J Mol Sci.2020, 21(7):2530.J Agric Food Chem....2021...Food Funct.2020, 11(2):1322-1333.Separations2021, 8(7),90.
Our products had been exported to the following research institutions and universities, And still growing.
Cancer Research Initatives Foun... (Malaysia)Florida A&M University (USA)Monash University (Australia)Universitas Airlangga (Indonesia)
Universidade do Porto (Portugal)University of Ioannina (Greece)Universidade Federal de Pernamb... (Brazil)University of Maryland (USA)
Johannes Gutenberg University M... (Germany)Northeast Normal University Cha... (China)Sanford Burnham Medical Researc... (USA)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Tissue Cell.2022, 75:101728.Neurochem Res.2021, s11064-021-03449-0Front. Physiol.2022, 790345.Food Addit Contam Part A.2021, 38(12):1985-1994.J Am Soc Mass Spectrom.2021, 32(9):2451-2462.Microb Pathog.2019, 131:128-134Clin Transl Oncol.2019, 10.1007BMC Complement Altern Med.2019, 19(1):11Pharmaceuticals (Basel).2021, 14(7):633.Spectrochim Acta A2019, 210:372-380
Related Screening Libraries
||Methylecgonine is a kind of anaesthetic.It in urine as an indicator of cocaine use.|
|Analyst. 2015 Sep 21;140(18):6254-9. |
|Rapid detection of cocaine, benzoylecgonine and methylecgonine in fingerprints using surface mass spectrometry.[Pubmed: 25977942]|
|Latent fingerprints provide a potential route to the secure, high throughput and non-invasive detection of drugs of abuse. In this study we show for the first time that the excreted metabolites of drugs of abuse can be detected in fingerprints using ambient mass spectrometry.
METHODS AND RESULTS:
Fingerprints and oral fluid were taken from patients attending a drug and alcohol treatment service. Gas chromatography mass spectrometry (GC-MS) was used to test the oral fluid of patients for the presence of cocaine and benzoylecgonine. The corresponding fingerprints were analysed using Desorption Electrospray Ionization (DESI) which operates under ambient conditions and Ion Mobility Tandem Mass Spectrometry Matrix Assisted Laser Desorption Ionization (MALDI-IMS-MS/MS) and Secondary Ion Mass Spectrometry (SIMS). The detection of cocaine, benzoylecgonine (BZE) and Methylecgonine (EME) in latent fingerprints using both DESI and MALDI showed good correlation with oral fluid testing. The sensitivity of SIMS was found to be insufficient for this application.
These results provide exciting opportunities for the use of fingerprints as a new sampling medium for secure, non-invasive drug detection. The mass spectrometry techniques used here offer a high level of selectivity and consume only a small area of a single fingerprint, allowing repeat and high throughput analyses of a single sample.
||The herbs of Erythroxylum coca
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Clin Chem. 1987 Jan;33(1):118-9. |
|Detection and confirmation of cocaine use by chromatographic analysis for methylecgonine in urine.[Pubmed: 3542285 ]|
|Methylecgonine is a common metabolite of cocaine in man.
METHODS AND RESULTS:
We prepared Methylecgonine and developed thin-layer chromatographic and gas-chromatographic methods for its detection in urine. Seventy urine specimens from our drug screening laboratory were tested by our method and by EMIT. Both methods were positive for 26 urines, and both were negative for 42 urines. The other two urines were shown to contain cocaine by GC/MS, and no detectable metabolites.
We thus demonstrated that detection of Methylecgonine and cocaine is as sensitive a test for cocaine use as EMIT.