ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Neuropharmacology2019, 151437J of Apicultural Research2020, 10.1080Journal of Food Hygiene and Safet...2019...iScience.2020, 23(2):100849.J Microbiol Biotechnol....2020...Bull. Natl. Mus. Nat. Sci....2021...Oncol Rep.2021, 46(2):166.Enzyme Microb Technol....2022...
Plants2022, 11(3),294.South African Journal of Botany...2021...Oncotarget.2017, 8(64):108006-108019J Cell Mol Med.2021, 25(5):2645-2654. Food Chem.2022, 373(Pt B):131364.Molecules.2021, 26(3):695. Int Immunopharmacol.2022, 106:108603.Appl. Sci.2021, 11(24),12080
Korean Herb. Med. Inf....2020...Appl. Sci.2020, 10(4),1304Biomed Pharmacother.2021, 137:111362.Asian J Beauty Cosmetol...2019...Appl. Sci.2020, 10(8),2804Phytomedicine.2020, 79, 153351Antioxidants (Basel).2021, 10(9):1487.
More...
Our products had been exported to the following research institutions and universities, And still growing.
University of Fribourg (Switzerland)Pennsylvania State University (USA)Tohoku University (Japan)Worcester Polytechnic Institute (USA)
Yale University (USA)Charles University in Prague (Czech Republic)University of Illinois (USA)University of East Anglia (United Kingdom)
The Institute of Cancer Research (United Kingdom)Sanford Burnham Prebys Medical ... (USA)Ateneo de Manila University (Philippines)
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Murralongin
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Korean J of Pharmacognosy2020, 51,49-54.Int J Mol Sci.2021, 22(11):5503.Aquaculture2019, 510:392-399Neuropharmacology.2018, 131:68-82Genes Genomics.2020, 10.1007Planta Med.2018, 84(6-07):465-474Toxins (Basel).2019, 11(10):E575J of App. Res. on Med&Aromatic Plants2020, 100291.Molecules2020, 25(4):892Appl. Sci.2021, 11(19),9343.
Related Screening Libraries
| Description: |
Murralongin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. |
| In vitro: |
| J Nat Prod. 2010 May 28;73(5):1012-4. | | Coumarins from Galipea panamensis and Their Activity against Leishmania panamensis.[Pubmed: 20423106 ] |
METHODS AND RESULTS:
Two new coumarin compounds (1 and 2), phebalosin (3), its derived artifact Murralongin (4), and murrangatin acetonide (5) were isolated from the leaves of Galipea panamensis. The structures of 1 and 2 were assigned as 7-{[(2R*)-3,3-dimethyloxiran-2-yl]methoxy}-8-[(2R*,3R*)-3-isopropenyloxiran-2-yl]-2H-chromen-2-one and 7-methoxy-8-(4-methyl-3-furyl)-2H-chromen-2-one, respectively, on the basis of their spectroscopic data (primarily NMR and MS). Compounds 1-3 were tested against axenic amastigote forms of Leishmania panamensis and displayed 50% effective concentrations (EC(50)) of 9.9, 10.5, and 14.1 microg/mL, respectively.
CONCLUSIONS:
These three compounds also displayed cytotoxicity (IC(50)) at concentrations of 9.7, 33.0, and 20.7 microg/mL, respectively, on human promonocytic U-937 cells. |
|
Murralongin Description
| Source: |
The herbs of Murraya exotica L. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.8715 mL |
19.3573 mL |
38.7147 mL |
77.4293 mL |
96.7867 mL |
| 5 mM |
0.7743 mL |
3.8715 mL |
7.7429 mL |
15.4859 mL |
19.3573 mL |
| 10 mM |
0.3871 mL |
1.9357 mL |
3.8715 mL |
7.7429 mL |
9.6787 mL |
| 50 mM |
0.0774 mL |
0.3871 mL |
0.7743 mL |
1.5486 mL |
1.9357 mL |
| 100 mM |
0.0387 mL |
0.1936 mL |
0.3871 mL |
0.7743 mL |
0.9679 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Arch Pharm Res. 2011 Apr;34(4):527-31. | | C-7 oxygenated coumarins from the fruits of Micromelum minutum.[Pubmed: 21544717] |
METHODS AND RESULTS:
A new 7-oxygenated coumarin, 7-demethylMurralonginol isovalerate (1), and a new natural product, Murralonginol (2), together with seven known 7-oxygenated coumarins, Murralonginol isovalerate (3), Murralongin (4), micromelin (5), scopoletin (6), microminutin (7), murrangatin (8), and minumicrolin (9), were isolated from the fruits of Micromelum minutum. The structures of these compounds were established on the basis of their 1D and 2D NMR spectroscopic data.
CONCLUSIONS:
Among these isolates, compounds 2 and 4 - 9 exhibited cytotoxicity against cholangiocarcinoma cell line, KKU-100. |
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