Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Quasipanaxatriol
    Quasipanaxatriol
    Information
    CAS No. 171903-78-9 Price $413 / 5mg
    Catalog No.CFN95248Purity>95%
    Molecular Weight458.7Type of CompoundTriterpenoids
    FormulaC30H50O3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $413 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Melbourne University (Australia)
  • Siksha O Anusandhan University (India)
  • University of Bonn (Germany)
  • Seoul National University (Korea)
  • University of South Australia (Australia)
  • University of Medicine and Phar... (Romania)
  • Molecular Biology Institute of ... (Spain)
  • Weizmann Institute of Science (Israel)
  • University of British Columbia (Canada)
  • Sant Gadge Baba Amravati Univer... (India)
  • Universidad de Buenos Aires (Argentina)
  • More...
  • Package
    Featured Products
    Syringin

    Catalog No: CFN99282
    CAS No: 118-34-3
    Price: $80/20mg
    Viscidulin III

    Catalog No: CFN97488
    CAS No: 92519-91-0
    Price: $318/5mg
    Ginsenoside Rk3

    Catalog No: CFN92593
    CAS No: 364779-15-7
    Price: $180/10mg
    5-O-Feruloylquinic acid

    Catalog No: CFN92889
    CAS No: 40242-06-6
    Price: $/mg
    Sibiricose A5

    Catalog No: CFN90645
    CAS No: 107912-97-0
    Price: $138/20mg
    Glychionide A

    Catalog No: CFN92280
    CAS No: 119152-50-0
    Price: $318/5mg
    Kushenol C

    Catalog No: CFN92391
    CAS No: 99119-73-0
    Price: $468/10mg

    Quasipanaxatriol

    Quasipanaxatriol
    Product Name Quasipanaxatriol
    CAS No.: 171903-78-9
    Catalog No.: CFN95248
    Molecular Formula: C30H50O3
    Molecular Weight: 458.7 g/mol
    Purity: >95%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: The roots of Panax ginseng C. A. Mey.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $413 / 5mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • Inflammation.2020, 43(5):1716-1728.
  • PLoS One.2017, 12(3):e0173585
  • J Korean Society of Food Science & Nutrition2021, 50(9): 962-970
  • PLoS One.2020, 15(2):e0220084.
  • Anat Rec2018, 24264
  • FASEB J.2019, 33(8):9685-9694
  • Analytical methods2019, 11(6)
  • Chemistry of Plant Materials.2016, 33-46
  • Biotechnol Bioeng.2020, 117(7):2198-2208.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Triterpenoids Compound Library
  • Biological Activity
    Description: Quasipanaxatriol can greatly enhance the cytotoxicity of the anti-cancer drugs in P388/ADM cells.
    In vitro:
    Planta Med 1995; 61(5): 409-413.
    Reversal of Daunomycin and Vinblastine Resistance in Multidrug-Resistant P388 Leukemia in vitro through Enhanced Cytotoxicity by Triterpenoids.[Reference: WebLink]

    METHODS AND RESULTS:
    Examined in vitro were the effects of some triterpenoids from Panax (Araliaceae) and Glycyrrhiza (Leguminosae) spp. on the sensitivity to daunomycin (DAU) and vinblastine (VBL) of adriamycin (ADM)-resistant P388 leukemia cells (P388/ADM), which were resistant to multiple anticancer drugs. Quasipanaxatriol, 20(S)-protopanaxatriol, ginsenoside Rh2, and compound K greatly enhanced the cytotoxicity of the anti-cancer drugs in P388/ADM cells. The extent of enhancement was different among the triterpene compounds; the 4- to 46-fold increase in DAU cytotoxicity was observed in P388/ADM cells in the presence of non-toxic or marginally toxic concentrations of individual compounds, while those for VBL were in the ratios of 2- to 37-fold. The maximum increase in cytotoxicity was observed with 50 µM Quasipanaxatriol; the resistance indices defined to be the ratios of the IC50 values for P388/ADM and P388 parental cells decreased from 79 to 1.7 and from 180 to 4.9 in the cases of DAU and VBL, respectively.
    CONCLUSIONS:
    The reversal of DAU resistance in P388/ADM by Quasipanaxatriol could be explained by the effective accumulation of the drugs mediated by the DAU-efflux blockage.
    Quasipanaxatriol Description
    Source: The roots of Panax ginseng C. A. Mey.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Isolappaol C

    Catalog No: CFN95225
    CAS No: 929905-15-7
    Price: $333/10mg
    Methylpicraquassioside B

    Catalog No: CFN95379
    CAS No: 1443757-89-8
    Price: $318/10mg
    3'-Angeloyloxy-4'-senecioyloxy-2',...

    Catalog No: CFN95123
    CAS No: 1221686-60-7
    Price: $398/5mg
    Batatasin IV

    Catalog No: CFN95319
    CAS No: 60347-67-3
    Price: $318/5mg
    Isorubrofusarin 10-gentiobioside

    Catalog No: CFN95119
    CAS No: 200127-93-1
    Price: $338/10mg
    Columbianetin beta-D-glucopyranosi...

    Catalog No: CFN95038
    CAS No: 55836-35-6
    Price: $288/5mg
    Rebaudioside F

    Catalog No: CFN95215
    CAS No: 438045-89-7
    Price: $268/5mg
    Pieceid-2''-O-gallate

    Catalog No: CFN95226
    CAS No: 105304-51-6
    Price: $318/10mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1801 mL 10.9004 mL 21.8007 mL 43.6015 mL 54.5019 mL
    5 mM 0.436 mL 2.1801 mL 4.3601 mL 8.7203 mL 10.9004 mL
    10 mM 0.218 mL 1.09 mL 2.1801 mL 4.3601 mL 5.4502 mL
    50 mM 0.0436 mL 0.218 mL 0.436 mL 0.872 mL 1.09 mL
    100 mM 0.0218 mL 0.109 mL 0.218 mL 0.436 mL 0.545 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Syringin

    Catalog No: CFN99282
    CAS No: 118-34-3
    Price: $80/20mg
    Viscidulin III

    Catalog No: CFN97488
    CAS No: 92519-91-0
    Price: $318/5mg
    Ginsenoside Rk3

    Catalog No: CFN92593
    CAS No: 364779-15-7
    Price: $180/10mg
    5-O-Feruloylquinic acid

    Catalog No: CFN92889
    CAS No: 40242-06-6
    Price: $/mg
    Sibiricose A5

    Catalog No: CFN90645
    CAS No: 107912-97-0
    Price: $138/20mg
    Glychionide A

    Catalog No: CFN92280
    CAS No: 119152-50-0
    Price: $318/5mg
    Kushenol C

    Catalog No: CFN92391
    CAS No: 99119-73-0
    Price: $468/10mg