N1,N5,N10-(E)-tri-p-coumaroylspermidine | CAS:364368-18-3

N1,N5,N10-(E)-tri-p-coumaroylspermidine

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Description:

N1,N5,N10-(E)-tri-p-coumaroylspermidine shows free radical-scavenging activity.

In vitro:

Natural Product Research, 2007, 21(8):726-732.

Antioxidant hydroxycinnamic acid derivatives isolated from Brazilian bee pollen.[Pubmed: 17616901]

One novel and three known hydroxycinnamic acid derivatives having antioxidant activities were isolated from a Brazilian bee pollen. They were identified as kaempferol 3-O-[2-O-p-coumaroyl]-α-L-arabinopyranoside, N1,N5,N10-tri-p-coumaroyl spermidine（N1,N5,N10-(E)-tri-p-coumaroylspermidine）, N1,N5,N10,N14-tetra-p-coumaroyl spermine, and monocaffeoyl-tri-p-coumaroyl spermine, respectively. The structure of the kaempferol glycoside was established on the basis of spectroscopic and chemical investigations.
CONCLUSIONS:
Among the isolated compounds, monocaffeoyl-tri-p-coumaroyl spermine showed the strongest free radical-scavenging activity, which was almost identical to that of α-tocopherol. On the other hand, the antioxidant effect of tri-p-coumaroyl spermidine on autooxidation of linoleic acid was strongest and nearly equal to that of α-tocopherol.

N1,N5,N10-(E)-tri-p-coumaroylspermidine Description

Source:	The herbs of Helianthus annuus L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Structure Identification:

Journal of Agricultural & Food Chemistry, 1999, 47(3):1223.

Lipid, polyamide, and flavonol phagostimulants for adult western corn rootworm from sunflower (Helianthus annuus L.) pollen.[Pubmed: 10552441]

METHODS AND RESULTS:
Adult Diabroticites including western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, consume pollen of corn, squash, sunflower, and other species. Short-chain neutral amino acids in methanol-water extracts of pollen have been previously identified in our laboratory as strong phagostimulants for Diabrotica. Bioassay-driven fractionation was used to characterize the interacting lipid and midpolarity phagostimulants for adult WCR in Giant Gray Stripe sunflower, Helianthus annuus L., pollen. Lipids rich in omega3-linolenic acid including triglycerides, free fatty acids, phosphatidylethanolamines, phosphatidic acids, and phosphatidylcholines were highly phagostimulatory. Other important phagostimulatory components included a hydroxycinnamic acid-polyamine amide, N(1),N(5),N(10)-tri[(E)-p-coumaroyl]spermidine(N1,N5,N10-(E)-tri-p-coumaroylspermidine), and a flavonol, quercetin beta-3-O-glucoside.
CONCLUSIONS:
The structural characteristics of these phagoactive compounds and their role in the pollinivory specialization of rootworm beetles are discussed.

CAS No.	364368-18-3	Price	$388 / 5mg
Catalog No.	CFN95256	Purity	>=98%
Molecular Weight	583.7	Type of Compound	Alkaloids
Formula	C₃₄H₃₇N₃O₆	Physical Description	Powder
Download	COA MSDS	Similar structural	Comparison (Web)

Product Name	N1,N5,N10-(E)-tri-p-coumaroylspermidine
CAS No.:	364368-18-3
Catalog No.:	CFN95256
Molecular Formula:	C₃₄H₃₇N₃O₆
Molecular Weight:	583.7 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Helianthus annuus L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$388 / 5mg

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7132 mL	8.566 mL	17.1321 mL	34.2642 mL	42.8302 mL
5 mM	0.3426 mL	1.7132 mL	3.4264 mL	6.8528 mL	8.566 mL
10 mM	0.1713 mL	0.8566 mL	1.7132 mL	3.4264 mL	4.283 mL
50 mM	0.0343 mL	0.1713 mL	0.3426 mL	0.6853 mL	0.8566 mL
100 mM	0.0171 mL	0.0857 mL	0.1713 mL	0.3426 mL	0.4283 mL

CFN95253	N1,N5,N10-(Z)-tri-p-coumaroylspermidine	131086-78-7	583.7	C₃₄H₃₇N₃O₆
CFN95254	Safflospermidine B	N/A	583.7	C₃₄H₃₇N₃O₆
CFN95255	Safflospermidine A	N/A	583.7	C₃₄H₃₇N₃O₆
CFN95256	N1,N5,N10-(E)-tri-p-coumaroylspermidine	364368-18-3	583.7	C₃₄H₃₇N₃O₆