ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $222.6 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Front Pharmacol.2022, 13:906763.Food Funct.2022, D1FO03838A.Appl. Sci.2020, 10(5),1713.Clin Exp Pharmacol Physiol....2015...Korean Journal of Pharmacognosy....2019...J Mol Recognit.2020, 33(2):e2819Br J Pharmacol.2018, 175(6):902-923Separation Science Plus...2022...
ACS Chem Biol.2019, 14(5):873-881In Vitro Cellular & Developmental...2021...J Control Release.2021, 336:159-168. PLoS One.2018, 13(3):e0193386Biofactors.2018, 44(2):168-179Sci Rep.2017, 7:40345Korean J of Pharmacognosy...2020...Exp Mol Med.2020, 52(4):629-642.
Biomed Pharmacother.2022, 146:112497.Front Pharmacol.2022, 13:883475.Research Square2021, March 3rd.Molecules.2021, 26(3):695. Evid Based Complement Alternat Me...2017...Chem Biol Interact.2018, 283:59-74Pharmaceuticals (Basel)....2021...
Our products had been exported to the following research institutions and universities, And still growing.
University of East Anglia (United Kingdom)University of Hull (United Kingdom)Shanghai Institute of Biochemis... (China)Wroclaw Medical University (Poland)
VIT University (India)Universidade Federal de Pernamb... (Brazil)Medizinische Universit?t Wien (Austria)Universitas islam negeri Jakarta (Indonesia)
S.N.D.T. Women's University (India)Michigan State University (USA)Subang Jaya Medical Centre (Malaysia)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Drug Dev Res.2020, doi: 10.1002PLoS One.2017, 12(8):e0181191Cell Biochem Funct.2018, 36(6):303-311Industrial Crops and Products2020, 146:112186Food Bioscience2022, 50:102187.Front Pharmacol.2021, 12:607403.Heliyon.2023, e12778.LWT2020, 110397Journal of Ginseng Research2019, 10.1016South African J of Botany2020, 135:50-57
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Alkaloids Compound Library
||Cuscutamine has luciferase-inducing activity and can significantly stimulate cancer cell proliferation|
|Planta Med . 2004 Apr;70(4):299-304. |
|Isolation of a new 15-membered macrocyclic glycolipid lactone, Cuscutic Resinoside a from the seeds of Cuscuta chinensis: a stimulator of breast cancer cell proliferation[Pubmed: 15095143]|
|While searching for new estrogenic compounds from the plant kingdom, we investigated an extract of the seeds of Cuscuta chinensis (Convolvulaceae) which showed potency for stimulating MCF-7 cell proliferation. A novel resin glycoside, cuscutic resinoside A ( 6) was isolated along with five known compounds from the extract. The structure was deduced from its spectral data as (11 S)-hydroxyhexadecanoic acid 11- O-alpha- L-(4- O-2 R,3 R-nilylrhamnopyranosyl)-(1-->2)- O-alpha- L-rhamnopyranosyl-(1,2-lactone) forming a unique 15-membered macrocyclic lactone. The compound significantly stimulated not only MCF-7 cell proliferation but also T47D human breast cancer cells at a concentration of 10 microM. Along with Cuscutamine ( 1) and kaempferol ( 4), 6 was tested in the transient luciferase reporter assay and was found to have different luciferase inducing activity characteristics from the other compounds. These results suggest that 6 stimulated cancer cell proliferation by a different mechanism from 1 and 4.|
||The herbs of Cuscuta reflexa
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Sep Sci . 2018 May;41(10):2169-2177. |
|Application of off-line two-dimensional high-performance countercurrent chromatography on the chloroform-soluble extract of Cuscuta auralis seeds[Pubmed: 29450982]|
|In this study, the chloroform-soluble extract of Cuscuta auralis was separated successfully using off-line two-dimensional high-performance countercurrent chromatography, yielding a γ-pyrone, two alkaloids, a flavonoid, and four lignans. The first-dimensional countercurrent separation using a methylene chloride/methanol/water (11:6:5, v/v/v) system yielded three subfractions (fractions I-III). The second-dimensional countercurrent separations, conducted on fractions I-III using n-hexane/ethyl acetate/methanol/water/acetic acid (5:5:5:5:0, 3:7:3:7:0, and 1:9:1:9:0.01, v/v/v/v/v) systems, gave maltol (1), (-)-(13S)-Cuscutamine (2), (+)-(13R)-Cuscutamine (3), (+)-pinoresinol (4), (+)-epipinoresinol (5), kaempferol (6), piperitol (7), and (9R)-hydroxy-d-sesamin (8). To the best of our knowledge, maltol was identified for the first time in Cuscuta species. Furthermore, this report details the first full assignment of spectroscopic data of two Cuscutamine epimers, (-)-(13S)-Cuscutamine and (+)-(13R)-Cuscutamine.|