Periglaucine A | CAS:1025023-04-4 | Manufacturer ChemFaces

Periglaucine A

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Ascorbic acid

Catalog No: CFN90048
CAS No: 50-81-7
Price: $30/20mg

Methylenetanshinquinone

Catalog No: CFN92179
CAS No: 67656-29-5
Price: $338/5mg

1-O-Acetyl britannilactone

Catalog No: CFN90219
CAS No: 681457-46-5
Price: $338/20mg

Arctiin

Catalog No: CFN99991
CAS No: 20362-31-6
Price: $30/20mg

20(R)-Ginsenoside Rg3

Catalog No: CFN98170
CAS No: 38243-03-7
Price: $60/20mg

Parishin E

Catalog No: CFN93115
CAS No: 952068-57-4
Price: $298/20mg

Isobutylshikonin

Catalog No: CFN92023
CAS No: 52438-12-7
Price: $268/10mg

Costunolide

Catalog No: CFN98928
CAS No: 553-21-9
Price: $40/20mg

Meloside A

Catalog No: CFN90132
CAS No: 60767-80-8
Price: $238/5mg

(+)-Longifolene

Catalog No: CFN70117
CAS No: 475-20-7
Price: $30/20mg

Description:

Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.

Targets:

HBV

In vitro:

J Nat Prod. 2008 May;71(5):760-3.

Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus.[Pubmed: 18396905]

METHODS AND RESULTS:
Four new hasubanane-type alkaloids, periglaucines A-D (1-4), and three known alkaloids, norruffscine (5), (-)-8-oxotetrahydropalmatine (6), and (-)-8-oxocanadine (7), were isolated from the aerial parts of Pericampylus glaucus. Their structures were elucidated on the basis of extensive NMR and EIMS data, and that of Periglaucine A (1) was confirmed by single-crystal X-ray diffraction.
CONCLUSIONS:
Alkaloids 1-4 inhibited hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells. (-)-8-Oxotetrahydropalmatine (6) possessed a high selectivity index (SI = 22.4) for HBsAg secretion of the Hep G2.2.15 cell line with an IC(50) value of 0.14 mM. Norruffscine (5) and (-)-8-oxotetrahydropalmatine (6) exhibited inhibitory activity against human immunodeficiency virus (HIV-1) with EC(50) values of 10.9 and 14.1 microM in C8166 cells (SI = 45.7 and 18.8), respectively.

Periglaucine A Description

Source:	The aerial parts of Pericampylus glaucus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Periglaucine A
Price:
CAS No.:	1025023-04-4
Catalog No.:	CFN99040
Molecular Formula:	C₂₀H₂₃NO₆
Molecular Weight:	373.4 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The aerial parts of Pericampylus glaucus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiviral Compound Library Alkaloids Compound Library HBV Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.6781 mL	13.3905 mL	26.7809 mL	53.5619 mL	66.9523 mL
5 mM	0.5356 mL	2.6781 mL	5.3562 mL	10.7124 mL	13.3905 mL
10 mM	0.2678 mL	1.339 mL	2.6781 mL	5.3562 mL	6.6952 mL
50 mM	0.0536 mL	0.2678 mL	0.5356 mL	1.0712 mL	1.339 mL
100 mM	0.0268 mL	0.1339 mL	0.2678 mL	0.5356 mL	0.6695 mL

CFN92332	Fenfangjine G	205533-81-9	433.5	C₂₂H₂₇NO₈
CFN98993	16-Oxoprometaphanine	58738-31-1	373.4	C₂₀H₂₃NO₆
CFN97167	Prometaphanine	6858-85-1	359.4	C₂₀H₂₅NO₅
CFN97858	Prostephanaberrine	105608-27-3	343.38	C₁₉H₂₁NO₅
CFN95808	Acutumine	17088-50-5	397.9	C₁₉H₂₄ClNO₆
CFN98640	Sinoacutine	4090-18-0	327.4	C₁₉H₂₁NO₄
CFN98831	Dihydrooxoepistephamiersine	51804-69-4	405.5	C₂₁H₂₇NO₇
CFN98965	Dihydroepistephamiersine 6-acetate	57361-74-7	433.5	C₂₃H₃₁NO₇
CFN98425	Stephavanine	33116-33-5	497.5	C₂₆H₂₇NO₉
CFN98830	Oxoepistephamiersine	51804-68-3	403.4	C₂₁H₂₅NO₇